Central nervous system（CNS）injuries remain a leading cause of functional disabilities worldwide,often resulting in permanent neurological impairments,due to the inability to repair and regenerate damaged connections...Central nervous system（CNS）injuries remain a leading cause of functional disabilities worldwide,often resulting in permanent neurological impairments,due to the inability to repair and regenerate damaged connections.A major contributing factor to this loss of regenerative capacity is the formation of glial scar tissue（Cregg et al.,2014）,traditionally regarded as a potent mechanical and molecular barrier to repair.展开更多
基金supported by the National Health and Medical Research Council(NHMRCAPP20140228)+2 种基金the Australian Research Council SRI Stem Cells Australiasupported by the State Government of Victoria and the Australian Governmentsupported by an NHMRC Senior Research Fellowship(APP1077677)
文摘Central nervous system（CNS）injuries remain a leading cause of functional disabilities worldwide,often resulting in permanent neurological impairments,due to the inability to repair and regenerate damaged connections.A major contributing factor to this loss of regenerative capacity is the formation of glial scar tissue（Cregg et al.,2014）,traditionally regarded as a potent mechanical and molecular barrier to repair.
