AIM: To evaluate computed tomography (CT) findings, useful to suggest the presence of refractory celiac disease (RCD) and enteropathy associated T cell lymphoma (EATL). METHODS: Coeliac disease (CD) patients...AIM: To evaluate computed tomography (CT) findings, useful to suggest the presence of refractory celiac disease (RCD) and enteropathy associated T cell lymphoma (EATL). METHODS: Coeliac disease (CD) patients were divided into two groups. Group Ⅰ : uncomplicated CD (n = 14) and RCD type Ⅰ (n = 10). Group Ⅱ : RCD type Ⅱ (n = 15) and EATL (n = 7). RESULTS: Both groups showed classic signs of CD on CT. Intussusception was seen in 1 patient in group Ⅰ vs 5 in group Ⅱ (P = 0.06). Lymphadenopathy was seen in 5 patients in group Ⅱ vs no patients in group Ⅰ (P = 0.01). Increased number of small mesenteric vessels was noted in 20 patients in group Ⅰ vs Ⅱ in group 11 (P = 0.02). Eleven patients (50%) in group 11 had a splenic volume 〈 122 cm^3 vs 4 in group Ⅰ (14%), 10 patients in group Ⅰ had a splenic volume 〉 196 cm^3 (66.7%) vs 5 in group Ⅱ (33.3%) P = 0.028. CONCLUSION: CT scan is a useful tool in discriminating between CD and (Pre) EATL. RCD Ⅱ and EATL showed more bowel wall thickening, lymphadenopathy and intussusception, less increase in number of small mesenteric vessels and a smaller splenic volume compared with CD and RCD Ⅰ.展开更多
文摘AIM: To evaluate computed tomography (CT) findings, useful to suggest the presence of refractory celiac disease (RCD) and enteropathy associated T cell lymphoma (EATL). METHODS: Coeliac disease (CD) patients were divided into two groups. Group Ⅰ : uncomplicated CD (n = 14) and RCD type Ⅰ (n = 10). Group Ⅱ : RCD type Ⅱ (n = 15) and EATL (n = 7). RESULTS: Both groups showed classic signs of CD on CT. Intussusception was seen in 1 patient in group Ⅰ vs 5 in group Ⅱ (P = 0.06). Lymphadenopathy was seen in 5 patients in group Ⅱ vs no patients in group Ⅰ (P = 0.01). Increased number of small mesenteric vessels was noted in 20 patients in group Ⅰ vs Ⅱ in group 11 (P = 0.02). Eleven patients (50%) in group 11 had a splenic volume 〈 122 cm^3 vs 4 in group Ⅰ (14%), 10 patients in group Ⅰ had a splenic volume 〉 196 cm^3 (66.7%) vs 5 in group Ⅱ (33.3%) P = 0.028. CONCLUSION: CT scan is a useful tool in discriminating between CD and (Pre) EATL. RCD Ⅱ and EATL showed more bowel wall thickening, lymphadenopathy and intussusception, less increase in number of small mesenteric vessels and a smaller splenic volume compared with CD and RCD Ⅰ.