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Development of Standard Reagents for Avian Influenza Virus Subtypes Diagnosis 被引量:1
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作者 Maria Angela Orsi Soraya Cecilia Albieri Camillo +6 位作者 Eluana Carolina Fortunato Christian Steffe Domingues Dilmara Reischak Margarida Maria Hoppner Zaroni Tania Rosária Pereira Freitas Terra A.Jenson janice c.pedersen 《Journal of Agricultural Science and Technology(A)》 2019年第1期26-37,共12页
Avian influenza(AI)is one of the most relevant viruses in the poultry industry.The AI virus(AIV)transmission from birds to human causing severe cases and mortality enhanced the magnitude of AI for public health.Conseq... Avian influenza(AI)is one of the most relevant viruses in the poultry industry.The AI virus(AIV)transmission from birds to human causing severe cases and mortality enhanced the magnitude of AI for public health.Consequently,the AIV diagnosis laboratories should be able to detect and identify endemic,epidemic and seasonal influenza strains and other wildlife influenza subtypes that cross the country’s borders.The development in quality controls in according with international rules comes to improve the performance of tests.With this purpose,the Brazilian Reference Laboratory for Avian Influenza(LANAGRO-SP)established a cooperation with the World Organization for Animal Health(OIE)to produce AIV master seeds,inactivated antigens and antiserum to attend the necessities of Brazil and other South America countries under the high quality control for all test.Seventeen of AIV master seed lots and seventeen of inactivated antigens lots produced reached hemagglutination(HA)titers of 1:512 and 1:256,respectively.In addition,fifteen AIV antiserum lots with hemagglutination inhibition(HI)titers reaching 1:4,096 were obtained.The AIV reference reagents produced and applied in laboratory routine successfully. 展开更多
关键词 AVIAN INFLUENZA virus reference REAGENTS SUBTYPES quality control Brazil
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