Underlying the regulation of mammalian gene expression at the level of transcription is the structure and modifications of chromatin. Understanding the twisting structures of DNA wrapped around histones and their high...Underlying the regulation of mammalian gene expression at the level of transcription is the structure and modifications of chromatin. Understanding the twisting structures of DNA wrapped around histones and their higher-level ordering allows us to peek into a vast regulatory landscape.展开更多
基金supported by the National Institutes of Health,United States,to Wei Li(Grant Nos.R01HG007538,R01CA193466,and R01CA228140)。
文摘Underlying the regulation of mammalian gene expression at the level of transcription is the structure and modifications of chromatin. Understanding the twisting structures of DNA wrapped around histones and their higher-level ordering allows us to peek into a vast regulatory landscape.
