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Spontaneous and iatrogenic dehydration in the elderly alone or in combination with antiplatelet/anticoagulation agents and risk of subdural hematoma
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作者 Elizabeth Wirkowski Jonas DeMuro +3 位作者 Adel Hanna jay yasen Rajiv Narain Susan Elcin 《World Journal of Cardiovascular Diseases》 2014年第1期1-4,共4页
Background and Purpose: To evaluate the role of preadmission conditions, dehydration specifically, in the development of subdural hematoma in the elderly. Methods: Retrospective chart review. Results: The most prevale... Background and Purpose: To evaluate the role of preadmission conditions, dehydration specifically, in the development of subdural hematoma in the elderly. Methods: Retrospective chart review. Results: The most prevalent pre-admission medical condition was hypertension, followed by atrial fibrillation, CAD, hyperlipidemia, diabetes, and cancer. Out of 95 patients, 69 (73%) had features of dehydration, 27% were on diuretics and 28% were on antiplatelet agents and anticoagulation. Conclusions: Elderly population is prone to dehydration. Overzealous use of diuretics especially in combination with anticoagulation or antiplatelet therapy can contribute to the development of subdural hematomas, both spontaneous and traumatic. 展开更多
关键词 SUBDURAL Hematoma DIURETICS AQUAPORINS Adverse Drug Events DEHYDRATION
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Concomitant H1N1 encephalopathy and acute ischemic stroke: A case report
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作者 Elzbieta Wirkowski jay yasen Christopher Bondoc 《World Journal of Cardiovascular Diseases》 2012年第2期99-101,共3页
Neurological complications of infection by the novel H1N1 virus have been described primarily in children. In adults, patients typically present with fever and respiratory symptoms, and may develop acute respi-ratory ... Neurological complications of infection by the novel H1N1 virus have been described primarily in children. In adults, patients typically present with fever and respiratory symptoms, and may develop acute respi-ratory distress syndrome, sepsis and stroke. We present a 45-year-old man whose presentation of aphasia and right hemiplegia were incongruent with the findings on MRI of a small acute ischemic stroke. He rapidly developed multi-organ failure and died. Nasal swab PCR obtained prior to death returned positive for influenza virus A/H1N1. At autopsy, a small acute hemorrhagic infarction in the left parietal lobe was present. We suspect that this was a car-dio-embolic stroke, probably triggered by H1N1 myocarditis. 展开更多
关键词 STROKE INFECTION
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