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Antibacterial forsterite (Mg_(2)SiO_(4)) scaffold: A promising bioceramic for load bearing applications 被引量:5
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作者 Rajan Choudhary Ankita Chatterjee +3 位作者 Senthil Kumar Venkatraman Sivasankar Koppala jayanthi abraham Sasikumar Swamiappan 《Bioactive Materials》 SCIE 2018年第3期218-224,共7页
In the current work,forsterite samples with different surface area were investigated for its antibacterial activity.Dissolution studies show that the lower degradation of forsterite compared to other silicate bioceram... In the current work,forsterite samples with different surface area were investigated for its antibacterial activity.Dissolution studies show that the lower degradation of forsterite compared to other silicate bioceramics,which is a desirable property for repairing bone defects.Forsterite scaffold shows superior compressive strength than the cortical bone after immersion in simulated body fluid.Bactericidal tests indicate that the forsterite had inhibition effect on the growth of clinical bacterial isolates.Forsterite may be a suitable candidate material for load bearing applications with enhanced mechanical properties and lower degradation rate. 展开更多
关键词 Magnesium silicate BONE ANTIBACTERIAL DISSOLUTION Mechanical stability
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An overview of pyrethroid insecticides 被引量:2
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作者 Anudurga Gajendiran jayanthi abraham 《Frontiers in Biology》 CAS CSCD 2018年第2期79-90,共12页
BACKGROUND: Pesticides are used to control various pests of agricultural crops worldwide. Despite their agricultural benefits, pesticides are often considered a serious threat to the environment because of their pers... BACKGROUND: Pesticides are used to control various pests of agricultural crops worldwide. Despite their agricultural benefits, pesticides are often considered a serious threat to the environment because of their persistence. Pyrethroids are synthetic derivates of pyrethrins, which are natural organic insecticides procured from the flowers of Chrysanthemum cinerariaefolium and C. coccineum. Pyrethroids are classified into two groups class Ⅰ and class Ⅱ-based on their toxicity and physical properties. These pyrethroids are now used in many synthetic insecticides and are highly specific against insects; they are generally used against mosquitoes. The prominent site of insecticidal action ofpyrethroids is the voltage-sensitive sodium channels. METHODS and RESULTS: Pyrethroids are found to be stable, and they persist in the environment for a long period. This article provides an overview of the different classes, structure, and insecticidal properties of pyrethroid. Furthermore, the toxicity of pyrethroids is also discussed with emphasis on bioremediation to alleviate pollution. CONCLUSIONS: The article focuses on various microorganisms used in the degradation ofpyrethroids, the molecular basis of degradation, and the role of carboxylesterase enzymes and genes in the detoxification of pyrethroid. 展开更多
关键词 pyrethrin carboxylesterase enzyme MINERALIZATION microbial degradation TOXICITY
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A review on melatonin action as therapeutic agent in cancer
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作者 Soumya Nair Sandra Suresh +2 位作者 Arya Kaniyassery Panchami Jaya jayanthi abraham 《Frontiers in Biology》 CAS CSCD 2018年第3期180-189,共10页
关键词 Melatonin CIRCADIAN rhythm breast cancer PINEAL gland MELATONIN therapy peripheral organ FUNCTIONING
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