Rebuilding transformation strategies in post-Ebola epidemics in Africa

Rebuilding transformation strategies in post-Ebola epidemics in West Africa requires long-term surveillance and strengthening health system preparedness to disease outbreak.This paper assesses reconstruction efforts from socio-cultural,economic and ecological transformation response approaches and strategies in improving sustainable survivors and affected communities livelihood and wellbeing.A comprehensive approach is required in the recovery and rebuilding processes.Investing in rebuilding transformation requires fostering evidence-based and effective engaging new investors partnership strengthening,financing community-based programmes ownership,novel socio-economic innovations strategies and tools against the evolving and future Ebola epidemics.Thus,there should be improved community partnership,health and economic rebuilding programmes to address mistrust and care underutilization,poverty and care access inequity at all levels.Implementing effective post-Ebola national‘One Health’approach coupled with climate change mitigation and adaptations strategies is urgent public health needs aiming at improving the quality healthcare access,delivery trust and uptake in anticipation of EVD immunization program,productivity and emerging economy.

Antioxidant Effect of Herbs and Spices on Copper Mediated Oxidation of Lower and Very Low Density Lipoprotein

AIM:The present study investigates the antioxidant effect of two extracts(hydrolyzed and non-hydrolyzed)of five herbs and eight spices in the prevention of LDL+VLDL oxidation promoted by cupric ion.METHODS:The polyphenolic concentrations of these extracts were measured using Folin-Ciocalteu reagent.The antioxidant quality was analyzed by the determination of lag-time,concentration of polyphenol that will inhibit 50%of oxidation of LDL+VLDL(IC50)and phenol antioxidant index(PAOXI). RESULTS:The hydrolyzed extracts had significant higher polyphenol concentration,longer lag-time,lower IC50 and higher PAOXI than the non-hydrolyzed extracts(P<0.001).Thus,hydrolyzed extract contains better quantity and quality polyphenolic antioxidant than the non-hydrolyzed extract.Both hydrolyzed and non-hydrolyzed extracts were better antioxidants than Vitamin E in the inhibition of LDL+VLDL oxidation.CONCLUSION:The reaction rate and concentration of conjugated diene formed suggested that all the extracts had similar reaction mechanism in the prevention of copper mediated LDL+VLDL oxidation.

Assessing the prevalence of urogenital schistosomaisis and transmission risk factors amongst school-aged children around Mapedam ecological suburbs in Malantouen district,Cameroon

Background:Urogenital schistosomiasis is a parasitic infection of public health importance that affects over 112 million people worldwide.The study aimed at assessing the urogenital schistosomiasis prevalence and risk factors of transmission around Mape dam suburds in Malantouen district,West,Cameroon.Methods:The study was conducted using semi-structured pretested questionnaires to collect socio-demographic and ecological data.Urine samples were also collected and used to confirm the prevalence of schistosomiasis in consented school-aged children in four primary schools between March-July 2014.Snails’samples around the dam surburbs were also collected for taxonomy characterization and species identification.Data were compiled and quality control assessed and analysed using SPSS version 17 and Epiinfo data 3.1.P<0.05 was considered statistical significance.Results:Questionnaires were administered to 229 pupils,with gender ratio of 1.04(m/f).The prevalence of schistosomiasis haematobium was 16.6%.Mambonko school site,which is the closest to the dam suburbs,registered the greatest prevalence rate of 40%.The age group beween 10-13 years was the most infected(18.3%)and boys were more infested than girls(21.0%vs.15.5%).Haematuria,urination pain,school absentiesm and poor performance were the major recorded complications in 39.5 and 26.3%males to female respectively.Infection rate gender disparity documented is still poorly understood and Bulinus truncatus collected from Mambonko suburb as potential snail intermediate host requires further studies.Conclusions:Authors advocated that schools and dam suburds sustained and innovative community-based surveillance and response targeted interventions implementation are needed to inform and support decisionmaking policy,but also in improving effective contextual behavioural communication changes and MDA improved uptake measures on national schistosomiasis control and elimination in Cameroon.