Multi-responsive hydrogels,or‘intelligent’hydrogels that respond to more than one environmental stimulus,have demonstrated great utility as a regenerative biomaterial in recent years.They are structured biocompatibl...Multi-responsive hydrogels,or‘intelligent’hydrogels that respond to more than one environmental stimulus,have demonstrated great utility as a regenerative biomaterial in recent years.They are structured biocompatible materials that provide specific and distinct responses to varied physiological or externally applied stimuli.As evidenced by a burgeoning number of investigators,multi-responsive hydrogels are endowed with tunable,controllable and even biomimetic behavior well-suited for drug delivery and tissue engineering or regenerative growth applications.This article encompasses recent developments and challenges regarding supramolecular,layer-by-layer assembled and covalently cross-linked multi-responsive hydrogel networks and their application to drug delivery and tissue engineering.展开更多
基金Preparation of this review article was supported in part by the National Science Foundation Graduate Research Fellowship Program[DGE-1110007 to J.M.K.].
文摘Multi-responsive hydrogels,or‘intelligent’hydrogels that respond to more than one environmental stimulus,have demonstrated great utility as a regenerative biomaterial in recent years.They are structured biocompatible materials that provide specific and distinct responses to varied physiological or externally applied stimuli.As evidenced by a burgeoning number of investigators,multi-responsive hydrogels are endowed with tunable,controllable and even biomimetic behavior well-suited for drug delivery and tissue engineering or regenerative growth applications.This article encompasses recent developments and challenges regarding supramolecular,layer-by-layer assembled and covalently cross-linked multi-responsive hydrogel networks and their application to drug delivery and tissue engineering.
