BACKGROUND It is difficult to restore the cognitive functions of patients with impaired cognition caused by brain injury.Diffusion tensor imaging can visualize the integrity of neural tracts in the white matter(WM)thr...BACKGROUND It is difficult to restore the cognitive functions of patients with impaired cognition caused by brain injury.Diffusion tensor imaging can visualize the integrity of neural tracts in the white matter(WM)three-dimensionally.It is unclear whether encephalitis following scrub typhus damages the WM.For the first time,we aimed to report diffusion tensor tractography(DTT)findings in a chronic patient with cognitive impairment following scrub typhus encephalitis,which revealed injury to the Papez circuit of the WM.CASE SUMMARY A 70-year-old male patient was affected by encephalitis caused by scrub typhus that occurred 23 years ago.He had poor cognition and his clinical examination findings were as follows:Mini-Mental Status Examination score,14;and handgrip strength(right/left,kg),32.3/31.3.DTT revealed serious injuries of the left thalamocingulate tract and right mammillothalamic tract in the Papez circuit,and a partial injury of the anterior part of the fornix.CONCLUSION Using DTT,we found a relationship between cognitive impairment and the integrity of the Papez circuit following scrub typhus.展开更多
Dear Editor,Anoxic brain injury(ABI)is a devastating event caused by cardiac arrest,chemical exposure,or trauma.Despite recent advances in medical diagnostic techniques and treatments,the survival rate after ABI is st...Dear Editor,Anoxic brain injury(ABI)is a devastating event caused by cardiac arrest,chemical exposure,or trauma.Despite recent advances in medical diagnostic techniques and treatments,the survival rate after ABI is still very low.Previous studies have reported that 52.6%-64.0%of people who received cardiopulmonary resuscitation after nontraumatic cardiac arrest die,and 9.0%-18.6%remain in a permanent vegetative state within 28 days of treatment[1,2].展开更多
基金National Research Foundation of Korea funded by the Ministry of Education,No.2013R1A1A4A01013178.
文摘BACKGROUND It is difficult to restore the cognitive functions of patients with impaired cognition caused by brain injury.Diffusion tensor imaging can visualize the integrity of neural tracts in the white matter(WM)three-dimensionally.It is unclear whether encephalitis following scrub typhus damages the WM.For the first time,we aimed to report diffusion tensor tractography(DTT)findings in a chronic patient with cognitive impairment following scrub typhus encephalitis,which revealed injury to the Papez circuit of the WM.CASE SUMMARY A 70-year-old male patient was affected by encephalitis caused by scrub typhus that occurred 23 years ago.He had poor cognition and his clinical examination findings were as follows:Mini-Mental Status Examination score,14;and handgrip strength(right/left,kg),32.3/31.3.DTT revealed serious injuries of the left thalamocingulate tract and right mammillothalamic tract in the Papez circuit,and a partial injury of the anterior part of the fornix.CONCLUSION Using DTT,we found a relationship between cognitive impairment and the integrity of the Papez circuit following scrub typhus.
基金supported by the Basic Science Research Program of the National Research Foundation of Korea funded by the Ministry of Education (2013R1A1A4A01013178)。
文摘Dear Editor,Anoxic brain injury(ABI)is a devastating event caused by cardiac arrest,chemical exposure,or trauma.Despite recent advances in medical diagnostic techniques and treatments,the survival rate after ABI is still very low.Previous studies have reported that 52.6%-64.0%of people who received cardiopulmonary resuscitation after nontraumatic cardiac arrest die,and 9.0%-18.6%remain in a permanent vegetative state within 28 days of treatment[1,2].
