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Control of CAR-T cell activity in space and time:the next level of anti-tumor action
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作者 jessica hoppstädter Alexandra K.Kiemer 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2023年第5期2035-2037,共3页
In two recent papers published in Science,advanced synthetic biology techniques were used to overcome the limitations of chimeric antigen receptor(CAR)-T cell therapy:In one case,CAR-T cells were successfully introduc... In two recent papers published in Science,advanced synthetic biology techniques were used to overcome the limitations of chimeric antigen receptor(CAR)-T cell therapy:In one case,CAR-T cells were successfully introduced into and maintained in solid tumors,1 and in another approach,CAR-T cell proliferation and activation could be turned on and off in a time-dependent manner by drug administration.2 These approaches might improve therapy for a large number of solid malignancies. 展开更多
关键词 CAR THERAPY OVERCOME
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