Photodynamic therapy (PDT) in combination with chemotherapy has great potential for cancer treatment (1, 2)However,there have been very few attempts to develop cancer-targeted co-delivery systems of photosensitizers a...Photodynamic therapy (PDT) in combination with chemotherapy has great potential for cancer treatment (1, 2)However,there have been very few attempts to develop cancer-targeted co-delivery systems of photosensitizers and anticancer drugs.We developed hematoporphyrin (HP)-modified doxorubicin(DOX)-loaded bovine serum albumin nanoparticles (HP-NPs) in an attempt to improve the therapeutic effect of PDT in treating liver cancer.展开更多
文摘Photodynamic therapy (PDT) in combination with chemotherapy has great potential for cancer treatment (1, 2)However,there have been very few attempts to develop cancer-targeted co-delivery systems of photosensitizers and anticancer drugs.We developed hematoporphyrin (HP)-modified doxorubicin(DOX)-loaded bovine serum albumin nanoparticles (HP-NPs) in an attempt to improve the therapeutic effect of PDT in treating liver cancer.