纪念性场地大约20年前,韩国政府在江南举办了“房博会”,建造了这座低层住宅的“世博小镇”,小镇的每一处建筑都是由当时韩国著名的建筑师精心设计的。“Ga On Jai(嘉稳斋)”曾是“博览城”之一。新主人购买了该地的老房子后,将它拆除,...纪念性场地大约20年前,韩国政府在江南举办了“房博会”,建造了这座低层住宅的“世博小镇”,小镇的每一处建筑都是由当时韩国著名的建筑师精心设计的。“Ga On Jai(嘉稳斋)”曾是“博览城”之一。新主人购买了该地的老房子后,将它拆除,重新建造了新房子。客户要求-最大程度上利用土地空间,赋予生态化“最大程度上利用土地空间,赋予生态化”是房主的重点要求,因为他认为被拆毁的老房子的外部空间狭窄、无用且内部空间呈蓝黑色。展开更多
Metal-based secondary building unit and the shape of organic ligands are the two crucial factors for determining the final topology of metal-organic materials.A careful choice of organic and inorganic structural build...Metal-based secondary building unit and the shape of organic ligands are the two crucial factors for determining the final topology of metal-organic materials.A careful choice of organic and inorganic structural building units occasionally produces unexpected structures,facilitating deeper fundamental understanding of coordination-driven self-assembly behind metal-organic materials.Here,we have synthesized a triangular metal-organic polygon(MOT-1),assembled from bulky tetramethyl terephthalate and Zr-based secondary building unit.Surprisingly,the Zr-based secondary building unit serves as an unusual ditopic Zr-connector,toform metal-organic polygon MOT-1,proven to be a good candidate for water adsorption with recyclability.This study highlights the interplay of the geometrically frustrated ligand and secondary building unit in controlling the connectivity of metal-organic polygon.Such a strategy can be further used to unveil a new class of metal-organic materials.展开更多
Objective： To evaluate the effects of botulinum toxin type A （BTX-A） on mandible skeletal development by inducing muscle hypofunction. Methods： Four-week-old Sprague-Dawley rats （n=60） were divided into three gr...Objective： To evaluate the effects of botulinum toxin type A （BTX-A） on mandible skeletal development by inducing muscle hypofunction. Methods： Four-week-old Sprague-Dawley rats （n=60） were divided into three groups： Group 1 animals served as controls and were injected with saline; Group 2 animals were injected unilaterally with BTX-A （the contralateral side was injected with saline）; and Group 3 animals were injected bilaterally with BTX-A. In Group 2, the saline-injected side was designated the control side （Group 2-1）, whereas the BTX-A-injected side was designated the experimental side （Group 2-2）. After four weeks, the animals were sacrificed, dry skulls were prepared, and mandibles were measured. Results： In the unilateral group, the experimental side （Group 2-2） had reduced di- mensions for all mandible measurements compared with the control side （Group 2-1）, suggesting a local effect of BTX-A on mandible growth, likely due to muscle reduction. Conclusions： Localized BTX-A injection induced a change in craniofacial growth, and the skeletal effect was unilateral despite both sides of the mandible functioning as one unit.展开更多
文摘纪念性场地大约20年前,韩国政府在江南举办了“房博会”,建造了这座低层住宅的“世博小镇”,小镇的每一处建筑都是由当时韩国著名的建筑师精心设计的。“Ga On Jai(嘉稳斋)”曾是“博览城”之一。新主人购买了该地的老房子后,将它拆除,重新建造了新房子。客户要求-最大程度上利用土地空间,赋予生态化“最大程度上利用土地空间,赋予生态化”是房主的重点要求,因为他认为被拆毁的老房子的外部空间狭窄、无用且内部空间呈蓝黑色。
基金Korea Environment Industry&Technology Institute(KEITI)through Public Technology Program based on Environmental Policy Program,funded by Korea M inistry of Environment(MOE)(No.2018000210002)National Research Foundation(NRF)of Korea(Nos.NRF-2016R1A5A1009405,NRF-2017M3C1B4051161)D.-W.L.and H.K.acknowledge the support from the ACCEL program Japan Science and Technology Agency(JST),JPMJAC1501.J.K.acknowledges the support from NRF Grant funded by the Korean Government(No.NRF-2018H1A2A1061391-Global Ph.D.Fellowship Program).We acknowledge the Pohang Accelerator Laboratory(PAL)for 2D beamline use(2019-1st-2D-038).We would like to thank Hyeonsoo Chofor providing 3D models for possible structures shown in Fig.8.
文摘Metal-based secondary building unit and the shape of organic ligands are the two crucial factors for determining the final topology of metal-organic materials.A careful choice of organic and inorganic structural building units occasionally produces unexpected structures,facilitating deeper fundamental understanding of coordination-driven self-assembly behind metal-organic materials.Here,we have synthesized a triangular metal-organic polygon(MOT-1),assembled from bulky tetramethyl terephthalate and Zr-based secondary building unit.Surprisingly,the Zr-based secondary building unit serves as an unusual ditopic Zr-connector,toform metal-organic polygon MOT-1,proven to be a good candidate for water adsorption with recyclability.This study highlights the interplay of the geometrically frustrated ligand and secondary building unit in controlling the connectivity of metal-organic polygon.Such a strategy can be further used to unveil a new class of metal-organic materials.
基金supported by the Samsung Biomedical Research Institute Grant(No.CA53061),Korea
文摘Objective： To evaluate the effects of botulinum toxin type A （BTX-A） on mandible skeletal development by inducing muscle hypofunction. Methods： Four-week-old Sprague-Dawley rats （n=60） were divided into three groups： Group 1 animals served as controls and were injected with saline; Group 2 animals were injected unilaterally with BTX-A （the contralateral side was injected with saline）; and Group 3 animals were injected bilaterally with BTX-A. In Group 2, the saline-injected side was designated the control side （Group 2-1）, whereas the BTX-A-injected side was designated the experimental side （Group 2-2）. After four weeks, the animals were sacrificed, dry skulls were prepared, and mandibles were measured. Results： In the unilateral group, the experimental side （Group 2-2） had reduced di- mensions for all mandible measurements compared with the control side （Group 2-1）, suggesting a local effect of BTX-A on mandible growth, likely due to muscle reduction. Conclusions： Localized BTX-A injection induced a change in craniofacial growth, and the skeletal effect was unilateral despite both sides of the mandible functioning as one unit.
