The incidence of hyperbilirubinemia is high clinically, which is difficult to cure by medication, surgery or interventional therapies. Non-bioartificial liver is the main alternative in the blood purification for hype...The incidence of hyperbilirubinemia is high clinically, which is difficult to cure by medication, surgery or interventional therapies. Non-bioartificial liver is the main alternative in the blood purification for hyperbilirubinemia, which includes plasma exchange, hemoperfusion, hemodialysis, molecular adsorbent recycling system and so on. The research results and clinical experiences in China show that these methods are effective in lowering high levels of bilirubin with fewer side effects. The hyperbilirubinemias of different causes, with different complications or accompanying different diseases can be treated by different methods. Bioartificial liver, hybrid artificial liver support system and adsorbent membrane material have also been studied and their development in reducing hyperbilirubinemias has been achieved. This article gives a brief overview on the actuality and research improvement in blood purification for hyperbilirubinemia in China.展开更多
Blood purification refers to the extra corporeal therapies of removing potentially toxic substances, in which blood is circulated through an adsorption system loading separation materials. High-efficient inexpensive s...Blood purification refers to the extra corporeal therapies of removing potentially toxic substances, in which blood is circulated through an adsorption system loading separation materials. High-efficient inexpensive separation materials are critical to success. In this review, separation materials such as polymers and nanomaterials are summarized and compared. Combining the advantages of the adsorptive membranes and nanomaterials, organic–inorganic hybrid/blend membranes have been developed explosively. These hybrid/blend membranes have both the characteristics of high permeability, easy fabrication, good biocompatibility of adsorptive membranes, and characteristics of fast adsorption rate and high adsorption capacity of nanomaterials. The preparation and modification methodology of the separation materials is reviewed. For affinity separation materials, the relationship of ligand chemistry, ligand density and pores of the matrix is discussed. This paper also summarizes some interesting applications in separation materials for removal of bilirubin, endotoxin, toxic metal ions, cytokine, etc.展开更多
Seven types of activated carbon were used to investigate the effect of their structure on separation of CO2 from（H2 ＋ CO2） gas mixture by the adsorption method at ambient temperature and higher pressures. The resul...Seven types of activated carbon were used to investigate the effect of their structure on separation of CO2 from（H2 ＋ CO2） gas mixture by the adsorption method at ambient temperature and higher pressures. The results showed that the limiting factors for separation of CO2 from 53.6 mol% H2 ＋ 46.4 mol% CO2 mixture and from 85.1 mol% H2 ＋ 14.9 mol% CO2 mixture were different at 20 °C and about 2 MPa. The best separation result could be achieved when the pore diameter of the activated carbon ranged from 0.77 to 1.20 nm, and the median particle size was about2.07 lm for 53.6 mol% H2 ＋ 46.4 mol% CO2 mixture and 1.41 lm for 85.1 mol% H2 ＋ 14.9 mol% CO2 mixture. The effect of specific area and pore diameter of activated carbon on separation CO2 from 53.6 mol% H2 ＋ 46.4 mol% CO2 mixture was more significant than that from 85.1 mol% H2 ＋ 14.9 mol% CO2 mixture. CO2 in the gas phase can be decreased from 46.4 mol% to 2.3 mol%–4.3 mol% with a two-stage separation process.展开更多
The report mainly shows the methods of Huawei and Lenovo’s managers to manage the organizations to achieve goals.First,it gives the overviews of Huawei and Lenovo which are two of the largest communication devices ma...The report mainly shows the methods of Huawei and Lenovo’s managers to manage the organizations to achieve goals.First,it gives the overviews of Huawei and Lenovo which are two of the largest communication devices manufacturers,provides a departmental structure.Second,it simply explains the meaning of management and management personnel in this report.Then,it analyzes Two-Factor Theory.It provides their successful cases with using Two-Factor Theory.Finally,it provides a conclusion of similarities and differences between them and offers recommendations.展开更多
In this work,a high-strength Mg-10Gd-2Y-1.5Zn-0.5Zr(wt%)alloy was prepared via eight passes of equal-channel angular pressing(ECAP).The microstructures and mechanical properties of as-cast and ECAP alloys were systema...In this work,a high-strength Mg-10Gd-2Y-1.5Zn-0.5Zr(wt%)alloy was prepared via eight passes of equal-channel angular pressing(ECAP).The microstructures and mechanical properties of as-cast and ECAP alloys were systematically investigated by X-ray diffraction(XRD),optical microscopy(OM),scanning electron microscopy(SEM),transmission electron microscopy(TEM)and electronic universal testing machine.The obtained results indicate that the microstructure of as-cast alloy consists ofα-Mg dendrite,network Mg3(Gd,Y,Zn)phase and lamellar 14H long-period stacking ordered(LPSO)phase which is precipitated near the boundary of Mg3(Gd,Y,Zn)networks.After eight-pass ECAP,the network Mg3(Gd,Y,Zn)phase is deformed and broken.However,the refined Mg_3(Gd,Y,Zn)particles are not distributed uniformly in the matrix,but still aggregated at the interdendritic area.Moreover,the content of 14H lamellas increases obviously,and they become bent and kinked during severe deformation.DRX is activated in the region between Mg3(Gd,Y,Zn)particles and 14H clusters.Compression test at room temperature indicates that the ECAP alloy exhibits excellent mechanical property with compressive strength of 518 MPa and fracture strain of 21.6%.The comprehensive high strength and toughness could be ascribed to the refined Mg_3(Gd,Y,Zn)particles,DRX grains and kinked 14H LPSO phase.展开更多
This study systematically investigated the influence of the microstructure evolution,mechanical properties and corrosion behaviors on Zn–1.5Mg(wt%)alloy processed by room-temperature rolling.The as-cast Zn–1.5Mg all...This study systematically investigated the influence of the microstructure evolution,mechanical properties and corrosion behaviors on Zn–1.5Mg(wt%)alloy processed by room-temperature rolling.The as-cast Zn–1.5Mg alloy consists ofη-Zn matrix andη-Zn+Mg_(2)Zn_(11)eutectic structure.As rolling reduction increases,the average grain size of the alloy reduces from 42.9 to 1.7μm,and the eutectic structure undergoes fragmentation and refinement,changing from a network distribution surrounding the matrix to a lamellar alternating distribution with the matrix.The ultimate tensile strength of the as-rolled alloy(80%reduction)is increased to 366±3.7 MPa,along with a good elongation of 18.4%±2.0%.Immersion tests in Hanks’solution indicate that the initial corrosion rate of the 80%-rolled alloy is 0.030 mm/year and finally stabilizes at 0.034 mm/year when the immersion duration is extended to 21 days.According to X-ray diffractometer and X-ray photoelectron spectroscopy analyses,Ca_(3)(PO_(4))_(2),CaCO_(3),Ca(OH)_(2),Zn_(3)(PO_(4))_(2),Zn(OH)_(2),ZnO and a small amount of MgO and MgCO_(3)are the main corrosion products on the surface.Due to the microstructure refinement,the developed alloy exhibits uniform corrosion,and the corrosion morphology is dominated by pitting pits.展开更多
The influence of rare earth element Dy on martensitic transformation and magnetic properties of Co-Ni-Al alloy was studied.The results showed that the microstructure of the sample has a dual-phase structure（γ-phase ...The influence of rare earth element Dy on martensitic transformation and magnetic properties of Co-Ni-Al alloy was studied.The results showed that the microstructure of the sample has a dual-phase structure（γ-phase and martensite）.The rare earth element Dy was segregated in Co-richγ-phase and took the place of Co after its addition into the Co-Ni-Al alloy.As Dy content increased to over 0.5at.%,the grain was refined and the rare earth intermetallic compounds Co5 Dy were precipitated inγ-phase.Meanwhile,one-step thermo-elastic martensitic transformation occurred in the sample,wherein the phase transformation temperature significantly increased with rising Dy content.The martensite had a tetragonal L10 structure with a（111）twinning plane.Furthermore,the sample exhibited obvious hysteresis behaviors in the magnetic hysteresis loops.In addition,the saturation magnetization,coercivity,retentivity and magnetocrystalline anisotropy were significantly enhanced owing to the bigger radius of Dy which took the place of Co in the alloy.展开更多
As a potential ferromagnetic shape memory alloy, Ni-Co-Al has excellent mechanical properties, large ma gentic-field-induced strain and high martensitic transformation temperature. The relationship between microstruct...As a potential ferromagnetic shape memory alloy, Ni-Co-Al has excellent mechanical properties, large ma gentic-field-induced strain and high martensitic transformation temperature. The relationship between microstructure and performance （mechanical and magnetic properties） of Ni-Co-Al with different Co/Al atomic ratios （RCo/Al） was investigated. Samples exhibit β and γ dual-phase structure. The γ phase grows coarse and the volume fraction of γ phase increases with the rise of RCo/Al. Besides, sample with high amount of γ phase content has smaller βgrains ow- ing to the pinning effect of γ phase. The martensite, transformed from β phase, is tetragonal L10 structure with a （111） twinning plane. The martensitic transformation temperature of samples ascends with increasing R co/Al owing to more Co embedded into the cell, which makes the valence electron concentration （e/a） of system rise. The satura- tion magnetization （Ms） of samples increases as Rco/Al rises because Co-rich 7 phase has excellent magnetic property. Meanwhile, both compressive and micro-hardness tests reveal that the samples containing more γ phase have excel- lent ductility due to the intrinsic good ductility nature of γ phase.展开更多
文摘The incidence of hyperbilirubinemia is high clinically, which is difficult to cure by medication, surgery or interventional therapies. Non-bioartificial liver is the main alternative in the blood purification for hyperbilirubinemia, which includes plasma exchange, hemoperfusion, hemodialysis, molecular adsorbent recycling system and so on. The research results and clinical experiences in China show that these methods are effective in lowering high levels of bilirubin with fewer side effects. The hyperbilirubinemias of different causes, with different complications or accompanying different diseases can be treated by different methods. Bioartificial liver, hybrid artificial liver support system and adsorbent membrane material have also been studied and their development in reducing hyperbilirubinemias has been achieved. This article gives a brief overview on the actuality and research improvement in blood purification for hyperbilirubinemia in China.
基金Supported by the National Natural Science Foundation of China(No.21606120)National Undergraducate Training Program for Innovation and Entrepreneurship(Nos.201710148000016 and 201810148080)
文摘Blood purification refers to the extra corporeal therapies of removing potentially toxic substances, in which blood is circulated through an adsorption system loading separation materials. High-efficient inexpensive separation materials are critical to success. In this review, separation materials such as polymers and nanomaterials are summarized and compared. Combining the advantages of the adsorptive membranes and nanomaterials, organic–inorganic hybrid/blend membranes have been developed explosively. These hybrid/blend membranes have both the characteristics of high permeability, easy fabrication, good biocompatibility of adsorptive membranes, and characteristics of fast adsorption rate and high adsorption capacity of nanomaterials. The preparation and modification methodology of the separation materials is reviewed. For affinity separation materials, the relationship of ligand chemistry, ligand density and pores of the matrix is discussed. This paper also summarizes some interesting applications in separation materials for removal of bilirubin, endotoxin, toxic metal ions, cytokine, etc.
基金the Talent Scientific Research Fund of LSHU (No. 2016XJJ-015)the fund of the Liaoning Provincial Department of Education (No. L2017LQN005)the National Natural Science Foundation of China (No. 21606120)
文摘Seven types of activated carbon were used to investigate the effect of their structure on separation of CO2 from（H2 ＋ CO2） gas mixture by the adsorption method at ambient temperature and higher pressures. The results showed that the limiting factors for separation of CO2 from 53.6 mol% H2 ＋ 46.4 mol% CO2 mixture and from 85.1 mol% H2 ＋ 14.9 mol% CO2 mixture were different at 20 °C and about 2 MPa. The best separation result could be achieved when the pore diameter of the activated carbon ranged from 0.77 to 1.20 nm, and the median particle size was about2.07 lm for 53.6 mol% H2 ＋ 46.4 mol% CO2 mixture and 1.41 lm for 85.1 mol% H2 ＋ 14.9 mol% CO2 mixture. The effect of specific area and pore diameter of activated carbon on separation CO2 from 53.6 mol% H2 ＋ 46.4 mol% CO2 mixture was more significant than that from 85.1 mol% H2 ＋ 14.9 mol% CO2 mixture. CO2 in the gas phase can be decreased from 46.4 mol% to 2.3 mol%–4.3 mol% with a two-stage separation process.
文摘The report mainly shows the methods of Huawei and Lenovo’s managers to manage the organizations to achieve goals.First,it gives the overviews of Huawei and Lenovo which are two of the largest communication devices manufacturers,provides a departmental structure.Second,it simply explains the meaning of management and management personnel in this report.Then,it analyzes Two-Factor Theory.It provides their successful cases with using Two-Factor Theory.Finally,it provides a conclusion of similarities and differences between them and offers recommendations.
基金financially supported by the Natural Science Foundation of Jiangsu Province of China(No.BK20160869)the Nantong Science and Technology Project(No.GY12015009)the Fundamental Research Funds for the Central Universities(No.2015B01314)。
文摘In this work,a high-strength Mg-10Gd-2Y-1.5Zn-0.5Zr(wt%)alloy was prepared via eight passes of equal-channel angular pressing(ECAP).The microstructures and mechanical properties of as-cast and ECAP alloys were systematically investigated by X-ray diffraction(XRD),optical microscopy(OM),scanning electron microscopy(SEM),transmission electron microscopy(TEM)and electronic universal testing machine.The obtained results indicate that the microstructure of as-cast alloy consists ofα-Mg dendrite,network Mg3(Gd,Y,Zn)phase and lamellar 14H long-period stacking ordered(LPSO)phase which is precipitated near the boundary of Mg3(Gd,Y,Zn)networks.After eight-pass ECAP,the network Mg3(Gd,Y,Zn)phase is deformed and broken.However,the refined Mg_3(Gd,Y,Zn)particles are not distributed uniformly in the matrix,but still aggregated at the interdendritic area.Moreover,the content of 14H lamellas increases obviously,and they become bent and kinked during severe deformation.DRX is activated in the region between Mg3(Gd,Y,Zn)particles and 14H clusters.Compression test at room temperature indicates that the ECAP alloy exhibits excellent mechanical property with compressive strength of 518 MPa and fracture strain of 21.6%.The comprehensive high strength and toughness could be ascribed to the refined Mg_3(Gd,Y,Zn)particles,DRX grains and kinked 14H LPSO phase.
基金the Key Research and Development Program of Jiangsu Province(BE2021027)the Project on Excellent Postgraduate Dissertation of Hohai University(422003518)+2 种基金the Postgraduate Research&Practice Innovation Program of Jiangsu Province(SJCX23_0175)the Opening Project of Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology(ASMA202102)the Jiangsu Key Laboratory for Light Metal Alloys(LMA202101).
文摘This study systematically investigated the influence of the microstructure evolution,mechanical properties and corrosion behaviors on Zn–1.5Mg(wt%)alloy processed by room-temperature rolling.The as-cast Zn–1.5Mg alloy consists ofη-Zn matrix andη-Zn+Mg_(2)Zn_(11)eutectic structure.As rolling reduction increases,the average grain size of the alloy reduces from 42.9 to 1.7μm,and the eutectic structure undergoes fragmentation and refinement,changing from a network distribution surrounding the matrix to a lamellar alternating distribution with the matrix.The ultimate tensile strength of the as-rolled alloy(80%reduction)is increased to 366±3.7 MPa,along with a good elongation of 18.4%±2.0%.Immersion tests in Hanks’solution indicate that the initial corrosion rate of the 80%-rolled alloy is 0.030 mm/year and finally stabilizes at 0.034 mm/year when the immersion duration is extended to 21 days.According to X-ray diffractometer and X-ray photoelectron spectroscopy analyses,Ca_(3)(PO_(4))_(2),CaCO_(3),Ca(OH)_(2),Zn_(3)(PO_(4))_(2),Zn(OH)_(2),ZnO and a small amount of MgO and MgCO_(3)are the main corrosion products on the surface.Due to the microstructure refinement,the developed alloy exhibits uniform corrosion,and the corrosion morphology is dominated by pitting pits.
文摘The influence of rare earth element Dy on martensitic transformation and magnetic properties of Co-Ni-Al alloy was studied.The results showed that the microstructure of the sample has a dual-phase structure（γ-phase and martensite）.The rare earth element Dy was segregated in Co-richγ-phase and took the place of Co after its addition into the Co-Ni-Al alloy.As Dy content increased to over 0.5at.%,the grain was refined and the rare earth intermetallic compounds Co5 Dy were precipitated inγ-phase.Meanwhile,one-step thermo-elastic martensitic transformation occurred in the sample,wherein the phase transformation temperature significantly increased with rising Dy content.The martensite had a tetragonal L10 structure with a（111）twinning plane.Furthermore,the sample exhibited obvious hysteresis behaviors in the magnetic hysteresis loops.In addition,the saturation magnetization,coercivity,retentivity and magnetocrystalline anisotropy were significantly enhanced owing to the bigger radius of Dy which took the place of Co in the alloy.
文摘As a potential ferromagnetic shape memory alloy, Ni-Co-Al has excellent mechanical properties, large ma gentic-field-induced strain and high martensitic transformation temperature. The relationship between microstructure and performance （mechanical and magnetic properties） of Ni-Co-Al with different Co/Al atomic ratios （RCo/Al） was investigated. Samples exhibit β and γ dual-phase structure. The γ phase grows coarse and the volume fraction of γ phase increases with the rise of RCo/Al. Besides, sample with high amount of γ phase content has smaller βgrains ow- ing to the pinning effect of γ phase. The martensite, transformed from β phase, is tetragonal L10 structure with a （111） twinning plane. The martensitic transformation temperature of samples ascends with increasing R co/Al owing to more Co embedded into the cell, which makes the valence electron concentration （e/a） of system rise. The satura- tion magnetization （Ms） of samples increases as Rco/Al rises because Co-rich 7 phase has excellent magnetic property. Meanwhile, both compressive and micro-hardness tests reveal that the samples containing more γ phase have excel- lent ductility due to the intrinsic good ductility nature of γ phase.
