BACKGROUND Hepatoid adenocarcinoma(HAC)occurs in extrahepatic organs such as the gastrointestinal tract,testes,ovaries,lungs,mediastinum and pancreas,and frequently produces a-fetoprotein(AFP).HAC of the lung(HAL)is r...BACKGROUND Hepatoid adenocarcinoma(HAC)occurs in extrahepatic organs such as the gastrointestinal tract,testes,ovaries,lungs,mediastinum and pancreas,and frequently produces a-fetoprotein(AFP).HAC of the lung(HAL)is rare,characterized by difficult treatment and poor prognosis.There are no reports of HAL in Yunnan-Guizhou Plateau,China.CASE S UMMARY A 60-year-old male patient was clinically diagnosed with HAL pT3 NOM0,stageⅡB.Chest computed tomography revealed a 7.5 cm x 7.2 cm soft tissue mass located in the right lung upper lobe and the adjacent superior mediastinum.Right upper lobectomy was performed.The diagnosis of HAL was confirmed by pathological examination,and the patient received paclitaxel and carboplatin as adjuvant chemotherapy after surgery.CONCL USION Clinical manifestations,pathological features,imaging findings,auxiliary examination,and treatment planning of HAL are presented to help clinicians improve their diagnosis and treatment.展开更多
基金Supported by the Yunnan Health Science and Technology Plan Project Task Book,No.2017NS020Yunnan Provincial Health and Family Planning Commission Reserve Talent Project,No.H-2017013+2 种基金Yunnan Provincial Science and Technology Project,No.2017FE467(-142)2018 CSCOQilu Tumor Project,No.YQ201802-011the Educational Reform Project of Kunming Medical University,No.2018-JY-Y-046
文摘BACKGROUND Hepatoid adenocarcinoma(HAC)occurs in extrahepatic organs such as the gastrointestinal tract,testes,ovaries,lungs,mediastinum and pancreas,and frequently produces a-fetoprotein(AFP).HAC of the lung(HAL)is rare,characterized by difficult treatment and poor prognosis.There are no reports of HAL in Yunnan-Guizhou Plateau,China.CASE S UMMARY A 60-year-old male patient was clinically diagnosed with HAL pT3 NOM0,stageⅡB.Chest computed tomography revealed a 7.5 cm x 7.2 cm soft tissue mass located in the right lung upper lobe and the adjacent superior mediastinum.Right upper lobectomy was performed.The diagnosis of HAL was confirmed by pathological examination,and the patient received paclitaxel and carboplatin as adjuvant chemotherapy after surgery.CONCL USION Clinical manifestations,pathological features,imaging findings,auxiliary examination,and treatment planning of HAL are presented to help clinicians improve their diagnosis and treatment.