Dynamic self-heating effect(SHE)of silicon-on-insulator(SOI)MOSFET is comprehensively evaluated by ultrafast pulsed I-V measurement in this work.It is found for the first time that the SHE complete heating response an...Dynamic self-heating effect(SHE)of silicon-on-insulator(SOI)MOSFET is comprehensively evaluated by ultrafast pulsed I-V measurement in this work.It is found for the first time that the SHE complete heating response and cooling response of SOI MOSFETs are conjugated,with two-stage curves shown.We establish the effective thermal transient response model with stage superposition corresponding to the heating process.The systematic study of SHE dependence on workload shows that frequency and duty cycle have more significant effect on SHE in first-stage heating process than in the second stage.In the first-stage heating process,the peak lattice temperature and current oscillation amplitude decrease by more than 25 K and 4%with frequency increasing to 10 MHz,and when duty cycle is reduced to 25%,the peak lattice temperature drops to 306 K and current oscillation amplitude decreases to 0.77%.Finally,the investigation of two-stage(heating and cooling)process provides a guideline for the unified optimization of dynamic SHE in terms of workload.As the operating frequency is raised to GHz,the peak temperature depends on duty cycle,and self-heating oscillation is completely suppressed.展开更多
Trigger characteristics of electrostatic discharge(ESD)protecting devices operating under various ambient temperatures ranging from 30℃to 195℃are investigated.The studied ESD protecting devices are the H-gate NMOS t...Trigger characteristics of electrostatic discharge(ESD)protecting devices operating under various ambient temperatures ranging from 30℃to 195℃are investigated.The studied ESD protecting devices are the H-gate NMOS transistors fabricated with a 0.18-μm partially depleted silicon-on-insulator(PDSOI)technology.The measurements are conducted by using a transmission line pulse(TLP)test system.The different temperature-dependent trigger characteristics of groundedgate(GGNMOS)mode and the gate-triggered(GTNMOS)mode are analyzed in detail.The underlying physical mechanisms related to the effect of temperature on the first breakdown voltage V_(T1)investigated through the assist of technology computer-aided design(TCAD)simulation.展开更多
Background:Both pre-operative anemia and perioperative(intra-and/or post-operative)blood transfusion have been reported to increase post-operative complications in patients with colon cancer undergoing colectomy.Howev...Background:Both pre-operative anemia and perioperative(intra-and/or post-operative)blood transfusion have been reported to increase post-operative complications in patients with colon cancer undergoing colectomy.However,their joint effect has not been investigated.The purpose of this study was to evaluate the joint effect of pre-operative anemia and perioperative blood transfusion on the post-operative outcome of colon-cancer patients after colectomy.Methods:We identified patients from the American College of Surgeons National Surgical Quality Improvement Program(NSQIP)database 2006–2016 who underwent colectomy for colon cancer.Multivariate logistic regression analysis was employed to assess the independent and joint effects of anemia and blood transfusion on patient outcomes.Results:A total of 35,863 patients—18,936(52.8%)with left-side colon cancer(LCC)and 16,927(47.2%)with right-side colon cancer(RCC)—were identified.RCC patients were more likely to have mild anemia(62.7%)and severe anemia(2.9%)than LCC patients(40.2%mild anemia and 1.4%severe anemia).A total of 2,661(7.4%)of all patients(1,079[5.7%]with LCC and 1,582[9.3%]with RCC)received a perioperative blood transfusion.Overall,the occurrence rates of complications were comparable between LCC and RCC patients(odds ratio[OR]=1.01;95%confidence interval[CI]=0.95–1.07;P=0.750).There were significant joint effects of anemia and transfusion on complications and the 30-day death rate(P for interaction:0.010).Patients without anemia who received a transfusion had a higher risk of any complications(LCC,OR=3.51;95%CI=2.55–4.85;P<0.001;RCC,OR=3.74;95%CI=2.50–5.59;P<0.001),minor complications(LCC,OR=2.54;95%CI=1.63–3.97;P<0.001;RCC,OR=2.27;95%CI=1.24–4.15;P=0.008),and major complications(LCC,OR=5.31;95%CI=3.68–7.64;P<0.001;RCC,OR=5.64;95%CI=3.61–8.79;P<0.001),and had an increased 30-day death rate(LCC,OR=6.97;95%CI=3.07–15.80;P<0.001;RCC,OR=4.91;95%CI=1.88–12.85;P=0.001)than patients without anemia who did not receive a transfusion.Conclusions:Pre-operative anemia and perioperative transfusion are associated with an increased risk of post-operative complications and increased death rate in colon-cancer patients undergoing colectomy.展开更多
文摘Dynamic self-heating effect(SHE)of silicon-on-insulator(SOI)MOSFET is comprehensively evaluated by ultrafast pulsed I-V measurement in this work.It is found for the first time that the SHE complete heating response and cooling response of SOI MOSFETs are conjugated,with two-stage curves shown.We establish the effective thermal transient response model with stage superposition corresponding to the heating process.The systematic study of SHE dependence on workload shows that frequency and duty cycle have more significant effect on SHE in first-stage heating process than in the second stage.In the first-stage heating process,the peak lattice temperature and current oscillation amplitude decrease by more than 25 K and 4%with frequency increasing to 10 MHz,and when duty cycle is reduced to 25%,the peak lattice temperature drops to 306 K and current oscillation amplitude decreases to 0.77%.Finally,the investigation of two-stage(heating and cooling)process provides a guideline for the unified optimization of dynamic SHE in terms of workload.As the operating frequency is raised to GHz,the peak temperature depends on duty cycle,and self-heating oscillation is completely suppressed.
基金the National Natural Science Foundation of China(Grant No.61804168)。
文摘Trigger characteristics of electrostatic discharge(ESD)protecting devices operating under various ambient temperatures ranging from 30℃to 195℃are investigated.The studied ESD protecting devices are the H-gate NMOS transistors fabricated with a 0.18-μm partially depleted silicon-on-insulator(PDSOI)technology.The measurements are conducted by using a transmission line pulse(TLP)test system.The different temperature-dependent trigger characteristics of groundedgate(GGNMOS)mode and the gate-triggered(GTNMOS)mode are analyzed in detail.The underlying physical mechanisms related to the effect of temperature on the first breakdown voltage V_(T1)investigated through the assist of technology computer-aided design(TCAD)simulation.
基金supported by the Beijing Municipal Science&Technology Commission[No.Z161100000116090]the National Key Research and Development Program of the Ministry of Science and Technology of China[No.2016YFC0905303]+1 种基金the CAMS Innovation Fund for Medical Sciences(CIFMS)[No.2016-I2M-1–001]the Beijing Science and Technology Program[No.D17110002617004].
文摘Background:Both pre-operative anemia and perioperative(intra-and/or post-operative)blood transfusion have been reported to increase post-operative complications in patients with colon cancer undergoing colectomy.However,their joint effect has not been investigated.The purpose of this study was to evaluate the joint effect of pre-operative anemia and perioperative blood transfusion on the post-operative outcome of colon-cancer patients after colectomy.Methods:We identified patients from the American College of Surgeons National Surgical Quality Improvement Program(NSQIP)database 2006–2016 who underwent colectomy for colon cancer.Multivariate logistic regression analysis was employed to assess the independent and joint effects of anemia and blood transfusion on patient outcomes.Results:A total of 35,863 patients—18,936(52.8%)with left-side colon cancer(LCC)and 16,927(47.2%)with right-side colon cancer(RCC)—were identified.RCC patients were more likely to have mild anemia(62.7%)and severe anemia(2.9%)than LCC patients(40.2%mild anemia and 1.4%severe anemia).A total of 2,661(7.4%)of all patients(1,079[5.7%]with LCC and 1,582[9.3%]with RCC)received a perioperative blood transfusion.Overall,the occurrence rates of complications were comparable between LCC and RCC patients(odds ratio[OR]=1.01;95%confidence interval[CI]=0.95–1.07;P=0.750).There were significant joint effects of anemia and transfusion on complications and the 30-day death rate(P for interaction:0.010).Patients without anemia who received a transfusion had a higher risk of any complications(LCC,OR=3.51;95%CI=2.55–4.85;P<0.001;RCC,OR=3.74;95%CI=2.50–5.59;P<0.001),minor complications(LCC,OR=2.54;95%CI=1.63–3.97;P<0.001;RCC,OR=2.27;95%CI=1.24–4.15;P=0.008),and major complications(LCC,OR=5.31;95%CI=3.68–7.64;P<0.001;RCC,OR=5.64;95%CI=3.61–8.79;P<0.001),and had an increased 30-day death rate(LCC,OR=6.97;95%CI=3.07–15.80;P<0.001;RCC,OR=4.91;95%CI=1.88–12.85;P=0.001)than patients without anemia who did not receive a transfusion.Conclusions:Pre-operative anemia and perioperative transfusion are associated with an increased risk of post-operative complications and increased death rate in colon-cancer patients undergoing colectomy.
