Hepatocellular carcinoma （HCC） is a malignant disease with limited therapeutic options due to its aggressive progression. It places heaW burden on most low and middle income countries to treat HCC patients. Nowadays...Hepatocellular carcinoma （HCC） is a malignant disease with limited therapeutic options due to its aggressive progression. It places heaW burden on most low and middle income countries to treat HCC patients. Nowadays accurate HCC risk predictions can help making decisions on the need for HCC surveillance and antiviral therapy. HCC risk prediction models based on major risk factors of HCC are useful and helpful in providing adequate surveillance strategies to individuals who have different risk levels. Several risk prediction models among cohorts of different populations for estimating HCC incidence have been presented recently by using simple, efficient, and ready-to-use parameters. Moreover, using predictive scoring systems to assess HCC development can provide suggestions to improve clinical and public health approaches, making them more cost-effective and effort-effective, for inducing personalized surveillance programs according to risk stratification. In this review, the features of risk prediction models of HCC across different populations were summarized, and the perspectives of HCC risk prediction models were discussed as well.展开更多
Non-design roll system crossing seriously affects the plate shape and rolling mill performance.The problem of roll system crossing caused by liner wear was studied.The finite element model of rolling mill was establis...Non-design roll system crossing seriously affects the plate shape and rolling mill performance.The problem of roll system crossing caused by liner wear was studied.The finite element model of rolling mill was established to analyze the relationship between roll system crossing and liner wear.The wear of liner was measured by laser tracker.The range of roll system crossing angle was calculated by considering the amount of stand clearance obtained by numerical simulation.The wear surface morphology of liner was observed and the wear mechanism was analyzed.The liner wear experiment was carried out to analyze the wear amount of the liner.Finally,based on the Archard wear theory,the prediction model of the cross angle of the roll system and the wear amount of the liner was established.Because there are more uncertain factors in the field production,the prediction model cannot be considered one by one.Therefore,the predicted value is smaller than the actual wear value,but it still has great reference.展开更多
基金supported by funds from the National Key Basic Research Program "973 project" (2015CB554000)the State Key Project Specialized for Infectious Diseases of China (No.2008ZX10002-015 and 2012ZX10002008-002)the Foundation for Innovative Research Groups of the National Natural Science Foundation of China (Grant No.81421001)
文摘Hepatocellular carcinoma （HCC） is a malignant disease with limited therapeutic options due to its aggressive progression. It places heaW burden on most low and middle income countries to treat HCC patients. Nowadays accurate HCC risk predictions can help making decisions on the need for HCC surveillance and antiviral therapy. HCC risk prediction models based on major risk factors of HCC are useful and helpful in providing adequate surveillance strategies to individuals who have different risk levels. Several risk prediction models among cohorts of different populations for estimating HCC incidence have been presented recently by using simple, efficient, and ready-to-use parameters. Moreover, using predictive scoring systems to assess HCC development can provide suggestions to improve clinical and public health approaches, making them more cost-effective and effort-effective, for inducing personalized surveillance programs according to risk stratification. In this review, the features of risk prediction models of HCC across different populations were summarized, and the perspectives of HCC risk prediction models were discussed as well.
基金funded by Central Government Guide Local Science and Technology Development Fund Project(No.216Z1602G)Major Science and Technology Projects of Shanxi province,China(No.20191102009).
文摘Non-design roll system crossing seriously affects the plate shape and rolling mill performance.The problem of roll system crossing caused by liner wear was studied.The finite element model of rolling mill was established to analyze the relationship between roll system crossing and liner wear.The wear of liner was measured by laser tracker.The range of roll system crossing angle was calculated by considering the amount of stand clearance obtained by numerical simulation.The wear surface morphology of liner was observed and the wear mechanism was analyzed.The liner wear experiment was carried out to analyze the wear amount of the liner.Finally,based on the Archard wear theory,the prediction model of the cross angle of the roll system and the wear amount of the liner was established.Because there are more uncertain factors in the field production,the prediction model cannot be considered one by one.Therefore,the predicted value is smaller than the actual wear value,but it still has great reference.
