Castleman disease(CD) is a rare disorder of lymph nodes and related tissues. CD generally occurs in the mediastinum, as well as in cervical, retroperitoneal and axillary regions. The disease is classified into two maj...Castleman disease(CD) is a rare disorder of lymph nodes and related tissues. CD generally occurs in the mediastinum, as well as in cervical, retroperitoneal and axillary regions. The disease is classified into two major types: unicentric CD(UCD) and multicentric CD. The occurrence of UCD in the retroperitoneal peripancreatic region is quite rare. We encountered two cases of retroperitoneal peripancreatic UCD in our hospital during the past three years. Following a series of medical examinations, including magnetic resonance imaging, computed tomography, ultrasonography and postoperative histopathological examination, these two patients were diagnosed with UCD,which presented as a retroperitoneal peripancreatic mass.The mass in each patient was completely excised,and no postoperative radiochemotherapy was administered.Both patients recovered well without recurrence during a follow-up period of 30 mo and 8 mo.展开更多
BACKGROUND Transduodenal ampullectomy(TDA) is not in wide clinical use due to its low radical effect and a high recurrence rate of tumors. However,TDA is still an effective treatment method; it has great clinical valu...BACKGROUND Transduodenal ampullectomy(TDA) is not in wide clinical use due to its low radical effect and a high recurrence rate of tumors. However,TDA is still an effective treatment method; it has great clinical value in cases of duodenal benign tumors,precancerous lesions,and benign and malignant borderline tumors,and can avoid the risks associated with pancreaticoduodenectomy with larger resection range and greater thoroughness than endoscopic papillectomy.AIM To investigate the surgical method choice and the coincidence rate of pathological diagnoses in TDA for ampullary neoplasms.METHODS Ten patients with ampullary neoplasms underwent TDA based on the fact that their endoscopic biopsy results suggested benign lesions,and the endoscopic ultrasound(EUS)-assessed tumors were resectable. All cases underwent duodenal ampullary lesion endoscopic biopsy,intraoperative frozen-section pathological examination,and postoperative pathological examination.RESULTSThis study included seven patients with benign tumors and three with malignant tumors(1 pTis,2 pT1),according to the postoperative pathology results. The coincidence rate of the postoperative pathology results with the intraoperative frozen-section biopsy results was 100%(10/10),and the coincidence rate with the endoscopic biopsy results was 70%(7/10) based on pathological characteristics.The endoscopic biopsy false-negative rate was 30%(3/10). All patients were followed for 6 to 70 mo without tumor recurrence or metastasis.CONCLUSION The coincidence rate of postoperative pathology results,intraoperative frozensection pathology results,and endoscopic biopsy results is the restraining factor of TDA clinical application. Endoscopic biopsy results and EUS have importance relevance to surgical planning. Intraoperative frozen-section pathology results have a significant influence on the choice of surgical procedure.展开更多
The counter-gravity casting methods have been developed to remove the casting defects of Mg based alloys. However, the effects of different counter-gravity casting methods on the microstructure and mechanical properti...The counter-gravity casting methods have been developed to remove the casting defects of Mg based alloys. However, the effects of different counter-gravity casting methods on the microstructure and mechanical properties have not been studied in detail. ZM5 alloys were prepared by gravity casting, low-pressure casting and counter-pressure casting, respectively. The mechanical properties, microstructure and fracture morphologies were examined and compared by means of optical microscopy, scanning electron microscopy methods and tensile testing. Results show that casting defects such as gas pore, shrinkage porosity and cavity can be eliminated by counter-pressure casting. The grain size of α-Mg is decreased significantly by counterpressure casting. Moreover, the precipitated particles are more uniform and finer in the counter-pressure casting sample. As a result, the mechanical properties of the alloys are greatly improved. The tensile strength and elongation of the samples by counter-pressure casting are 285 MPa and 13.9%, respectively, which are much higher than those of the low pressure casting and gravity casting.展开更多
A new structural parameter of amorphous alloys called atomic bond proportion was proposed, and a topological algorithm for the structural parameter was proven feasible in the previous work. In the present study, a cor...A new structural parameter of amorphous alloys called atomic bond proportion was proposed, and a topological algorithm for the structural parameter was proven feasible in the previous work. In the present study, a correction factor, λ,is introduced to optimize the algorithm and dramatically improve the calculation accuracy of the atomic bond proportion.The correction factor represents the ability of heterogeneous atoms to combine with one another to form the metallic bonds and it is associated with the uniformity of the master alloy, mixing enthalpy, cooling rate during preparation, and annealing time. The correction factor provides a novel pathway for researching the structures of the amorphous alloys.展开更多
The isothermal oxidation behavior of a new Refree nickel-based single-crystal superalloy in air at 950 ℃ for 200 h was studied by scanning electron microscopy（SEM）with energy-dispersive spectroscopy（EDS）and X-ray...The isothermal oxidation behavior of a new Refree nickel-based single-crystal superalloy in air at 950 ℃ for 200 h was studied by scanning electron microscopy（SEM）with energy-dispersive spectroscopy（EDS）and X-ray diffraction（XRD）.The results indicate that oxidation kinetics obeys parabolic law approximately,and the mass gain increases rapidly during initial oxidation stage and then gradually slows down.The oxidation scales are composed of three layers：the outer layer mainly consists of NiO with a small amount of CoO;the intermediate layer is mainly composed of Cr_2O_3 with a small amount of spinel compounds such as CrTaO_4,NiCr_2O_4,CoCrAl_2O_4,CoAl_2O_4,and NiAl_2O_4;and the inner layer is composed of Al_2O_3.Inner Al_2O_3 layer suppresses the diffusion of elements between oxygen and alloy elements,slows down the alloy oxidation speed,and also suppresses the growth of the oxide scale and reduces the oxidation rate,which is agreeable with the oxidation kinetics.展开更多
The effect of oxygen on the microstructure evolution and glass formation of Zr-based bulk metallic glasses（BMGs）was studied in detail.It was found that oxygen did not form oxides or dissolve in glass matrix,but indu...The effect of oxygen on the microstructure evolution and glass formation of Zr-based bulk metallic glasses（BMGs）was studied in detail.It was found that oxygen did not form oxides or dissolve in glass matrix,but induced the precipitation ofα-Zr which has the high affinity and solubility of oxygen in the Zr-based bulk metallic glass（ZrBMG）.With the precipitation ofα-Zr,the remaining melts contain much lower oxygen content and have strong glass formation,resulting in the formation ofα-Zr/BMG composite.The findings provide an important insight into the mechanism of the oxygen on glass formation,and give us a useful guideline to avoid the oxygen detrimental for designing new BMGs.展开更多
基金Supported by the Key Research and Development Plan of Shandong Province,No.2016GSF201108
文摘Castleman disease(CD) is a rare disorder of lymph nodes and related tissues. CD generally occurs in the mediastinum, as well as in cervical, retroperitoneal and axillary regions. The disease is classified into two major types: unicentric CD(UCD) and multicentric CD. The occurrence of UCD in the retroperitoneal peripancreatic region is quite rare. We encountered two cases of retroperitoneal peripancreatic UCD in our hospital during the past three years. Following a series of medical examinations, including magnetic resonance imaging, computed tomography, ultrasonography and postoperative histopathological examination, these two patients were diagnosed with UCD,which presented as a retroperitoneal peripancreatic mass.The mass in each patient was completely excised,and no postoperative radiochemotherapy was administered.Both patients recovered well without recurrence during a follow-up period of 30 mo and 8 mo.
基金Supported by the Key Research and Development Plan of Shandong Province,No.2016GSF201108
文摘BACKGROUND Transduodenal ampullectomy(TDA) is not in wide clinical use due to its low radical effect and a high recurrence rate of tumors. However,TDA is still an effective treatment method; it has great clinical value in cases of duodenal benign tumors,precancerous lesions,and benign and malignant borderline tumors,and can avoid the risks associated with pancreaticoduodenectomy with larger resection range and greater thoroughness than endoscopic papillectomy.AIM To investigate the surgical method choice and the coincidence rate of pathological diagnoses in TDA for ampullary neoplasms.METHODS Ten patients with ampullary neoplasms underwent TDA based on the fact that their endoscopic biopsy results suggested benign lesions,and the endoscopic ultrasound(EUS)-assessed tumors were resectable. All cases underwent duodenal ampullary lesion endoscopic biopsy,intraoperative frozen-section pathological examination,and postoperative pathological examination.RESULTSThis study included seven patients with benign tumors and three with malignant tumors(1 pTis,2 pT1),according to the postoperative pathology results. The coincidence rate of the postoperative pathology results with the intraoperative frozen-section biopsy results was 100%(10/10),and the coincidence rate with the endoscopic biopsy results was 70%(7/10) based on pathological characteristics.The endoscopic biopsy false-negative rate was 30%(3/10). All patients were followed for 6 to 70 mo without tumor recurrence or metastasis.CONCLUSION The coincidence rate of postoperative pathology results,intraoperative frozensection pathology results,and endoscopic biopsy results is the restraining factor of TDA clinical application. Endoscopic biopsy results and EUS have importance relevance to surgical planning. Intraoperative frozen-section pathology results have a significant influence on the choice of surgical procedure.
基金financially supported by the Shanghai Sailing Program(Grant No.18QB1401400)the Science Foundation for the Excellent Youth Scholars of Jiangsu Province
文摘The counter-gravity casting methods have been developed to remove the casting defects of Mg based alloys. However, the effects of different counter-gravity casting methods on the microstructure and mechanical properties have not been studied in detail. ZM5 alloys were prepared by gravity casting, low-pressure casting and counter-pressure casting, respectively. The mechanical properties, microstructure and fracture morphologies were examined and compared by means of optical microscopy, scanning electron microscopy methods and tensile testing. Results show that casting defects such as gas pore, shrinkage porosity and cavity can be eliminated by counter-pressure casting. The grain size of α-Mg is decreased significantly by counterpressure casting. Moreover, the precipitated particles are more uniform and finer in the counter-pressure casting sample. As a result, the mechanical properties of the alloys are greatly improved. The tensile strength and elongation of the samples by counter-pressure casting are 285 MPa and 13.9%, respectively, which are much higher than those of the low pressure casting and gravity casting.
基金Project supported by Excellent Youth Foundation of Jiangsu Scientific Committee,China(Grant No.BK20180106)the National Natural Science Foundation of China(Grant No.51804091)+1 种基金Industry-University-Research Cooperation Project of Jiangsu Province,China(Grant No.BY2020383)Opening Project of State Key Laboratory of Metastable Materials Science and Technology(Grant No.201910).
文摘A new structural parameter of amorphous alloys called atomic bond proportion was proposed, and a topological algorithm for the structural parameter was proven feasible in the previous work. In the present study, a correction factor, λ,is introduced to optimize the algorithm and dramatically improve the calculation accuracy of the atomic bond proportion.The correction factor represents the ability of heterogeneous atoms to combine with one another to form the metallic bonds and it is associated with the uniformity of the master alloy, mixing enthalpy, cooling rate during preparation, and annealing time. The correction factor provides a novel pathway for researching the structures of the amorphous alloys.
基金financially supported by Jiangsu Province Key Technology R&D(Industry)Program(No.BE201217)the Science and Technology Innovation Fund Program(Nos.CX2011028 and CX2011029)+1 种基金the Cooperative Innovation Fund of Jiangsu Province(No.BY2014004-09)the Foundation of Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology(No.ASMA201403)
文摘The isothermal oxidation behavior of a new Refree nickel-based single-crystal superalloy in air at 950 ℃ for 200 h was studied by scanning electron microscopy（SEM）with energy-dispersive spectroscopy（EDS）and X-ray diffraction（XRD）.The results indicate that oxidation kinetics obeys parabolic law approximately,and the mass gain increases rapidly during initial oxidation stage and then gradually slows down.The oxidation scales are composed of three layers：the outer layer mainly consists of NiO with a small amount of CoO;the intermediate layer is mainly composed of Cr_2O_3 with a small amount of spinel compounds such as CrTaO_4,NiCr_2O_4,CoCrAl_2O_4,CoAl_2O_4,and NiAl_2O_4;and the inner layer is composed of Al_2O_3.Inner Al_2O_3 layer suppresses the diffusion of elements between oxygen and alloy elements,slows down the alloy oxidation speed,and also suppresses the growth of the oxide scale and reduces the oxidation rate,which is agreeable with the oxidation kinetics.
基金Item Sponsored by National Natural Science Foundation of China(51401104,51271093)Natural Science Foundation of Jiangsu Province of China(BK20140765)+1 种基金Jiangsu Natural Science Foundation for Distinguished Young Scholars of China(BK20140035)supported by the Opening Project of Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology ASMA201413 and ASMA201403
文摘The effect of oxygen on the microstructure evolution and glass formation of Zr-based bulk metallic glasses（BMGs）was studied in detail.It was found that oxygen did not form oxides or dissolve in glass matrix,but induced the precipitation ofα-Zr which has the high affinity and solubility of oxygen in the Zr-based bulk metallic glass（ZrBMG）.With the precipitation ofα-Zr,the remaining melts contain much lower oxygen content and have strong glass formation,resulting in the formation ofα-Zr/BMG composite.The findings provide an important insight into the mechanism of the oxygen on glass formation,and give us a useful guideline to avoid the oxygen detrimental for designing new BMGs.
