CO_(2) immiscible flooding is an environmentally-friendly and effective method to enhance oil recovery in ultra-low permeability reservoirs.A mathematical model of CO_(2) immiscible flooding was developed,considering ...CO_(2) immiscible flooding is an environmentally-friendly and effective method to enhance oil recovery in ultra-low permeability reservoirs.A mathematical model of CO_(2) immiscible flooding was developed,considering the variation in crude oil viscosity and starting pressure gradient in ultra-low permeability reservoirs based on the non-Darcy percolation theory.The mathematical model and numerical simulator were developed in the C++language to simulate the effects of fluid viscosity,starting pressure gradient,and other physical parameters on the distribution of the oil pressure field,oil saturation field,gas saturation field,oil viscosity field,and oil production.The results showed that the formation pressure and pressure propagation velocity in CO_(2) immiscible flooding were lower than the findings without considering the starting pressure gradient.The formation oil content saturation and the crude oil formation viscosity were higher after the consideration of the starting pressure gradient.The viscosity of crude oil considering the initiation pressure gradient during the formation was higher than that without this gradient,but the yield was lower than that condition.Our novel mathematical models helped the characterization of seepage resistance,revealed the influence of fluid property changes on seepage,improved the mathematical model of oil seepage in immiscible flooding processes,and guided the improvement of crude oil recovery in immiscible flooding processes.展开更多
Dear Editor,Tremendous efforts have been made globally to develop therapeutics and prophylactics against severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)which has caused thousands of millions of infections ...Dear Editor,Tremendous efforts have been made globally to develop therapeutics and prophylactics against severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)which has caused thousands of millions of infections and deaths worldwide.A series of potent neutralizing antibodies with defined epitopes targeting RBD have been recently identified with different strategies.However,being an RNA virus,the instability of the SARS-CoV-2 genome results in numerous S-protein variants with altered viral phenotypes.展开更多
基金the Dongying Science Development Fund Project(Nos.DJ2022009 and DJ2020003)the Shandong Provincial Higher Education Research and Development Program(Science and Technology A Class)(No.J18KA201)+2 种基金the High-level Talent Research Start-up Fund of Shengli College of China University of Petroleum(No.KQ2019-008)the Chunhui Project of Shengli College of China University of Petroleum(No.KY2017004)the Research Cultivation Project of College of Big Data and Basic Science of Shandong Institute of Petroleum and Chemical Technology(No.XYPY2201)which supports are appreciated.
文摘CO_(2) immiscible flooding is an environmentally-friendly and effective method to enhance oil recovery in ultra-low permeability reservoirs.A mathematical model of CO_(2) immiscible flooding was developed,considering the variation in crude oil viscosity and starting pressure gradient in ultra-low permeability reservoirs based on the non-Darcy percolation theory.The mathematical model and numerical simulator were developed in the C++language to simulate the effects of fluid viscosity,starting pressure gradient,and other physical parameters on the distribution of the oil pressure field,oil saturation field,gas saturation field,oil viscosity field,and oil production.The results showed that the formation pressure and pressure propagation velocity in CO_(2) immiscible flooding were lower than the findings without considering the starting pressure gradient.The formation oil content saturation and the crude oil formation viscosity were higher after the consideration of the starting pressure gradient.The viscosity of crude oil considering the initiation pressure gradient during the formation was higher than that without this gradient,but the yield was lower than that condition.Our novel mathematical models helped the characterization of seepage resistance,revealed the influence of fluid property changes on seepage,improved the mathematical model of oil seepage in immiscible flooding processes,and guided the improvement of crude oil recovery in immiscible flooding processes.
基金supported by ShanghaiTech,Shanghai Frontiers Science Center for Biomacromolecules and Precision Medicine at ShanghaiTech University(G.Z.),and grants from the National Key Research and Development Program of China[Grant Nos.2017YFC1001301(G.Z.),2019YFA0111001(H.W.)]the National Natural Science Foundation of China[Nos.31670919(H.W.),81822045(L.L.)]+1 种基金Lingang Laboratory(No.LG202101-01-07 to X.Y.),Program of Shanghai Academic/Technology Research Leader[20XD1420300(L.L.)]Emergency response to new coronavirus infection scientific and technological project[YD9110002004(J.W.)],and Shanghai Sailing Program[20YF1430900(S.-M.Z.)].
文摘Dear Editor,Tremendous efforts have been made globally to develop therapeutics and prophylactics against severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)which has caused thousands of millions of infections and deaths worldwide.A series of potent neutralizing antibodies with defined epitopes targeting RBD have been recently identified with different strategies.However,being an RNA virus,the instability of the SARS-CoV-2 genome results in numerous S-protein variants with altered viral phenotypes.
