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利用和频振动光谱探索蛋白质与多肽界面结构的最新研究进展
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作者 王百惠 白亦敏 +4 位作者 彭佳惠 张苗苗 张伟婷 边红涛 房喻 《Chinese Journal of Chemical Physics》 SCIE EI CAS CSCD 2024年第2期398-410,I0105,共14页
蛋白质和多肽的界面结构在各种生物过程和技术发展中发挥着重要作用。对这些结构的深入了解对于疾病诊断、药物输送和生物材料的研究至关重要.然而,这些体系的复杂性以及分析方法的局限性限制了其深入研究.尽管X射线晶体学和低温电子显... 蛋白质和多肽的界面结构在各种生物过程和技术发展中发挥着重要作用。对这些结构的深入了解对于疾病诊断、药物输送和生物材料的研究至关重要.然而,这些体系的复杂性以及分析方法的局限性限制了其深入研究.尽管X射线晶体学和低温电子显微镜等先进技术在分析蛋白质结构方面做出了重大贡献,但对于实际条件下表面结合蛋白质结构的理解仍然有限,这也为该领域带来了挑战。和频振动光谱技术已经成为分析蛋白质界面分子结构的一种强有力的手段.本文简要介绍和频振动光谱学的基本原理,探讨其在相位测量方面的研究进展,并概述了近三年(2021~2023)的研究成果,展示了和频振动光谱在揭示多肽和蛋白质界面分子结构方面的潜力:本文为进一步利用和频振动光谱探索不同类型的多肽和蛋白质在界面上的结构和功能提供了有利的支持。 展开更多
关键词 蛋白质 多肽 结构 界面 和频振动光谱
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A Copyright-Preserving and Fair Image Trading SchemeBased on Blockchain
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作者 Feng Yu jiahui peng +2 位作者 Xianxian Li Chunpei Li Bin Qu 《Tsinghua Science and Technology》 SCIE EI CAS CSCD 2023年第5期849-861,共13页
With the proliferation of the Internet,particularly the rise of social media,digital images have gradually become an important part of life,and trading platforms have emerged for buying and selling images.However,trad... With the proliferation of the Internet,particularly the rise of social media,digital images have gradually become an important part of life,and trading platforms have emerged for buying and selling images.However,traditional image trading service providers may disclose users’private information for profit.Additionally,many image trading platforms disregard the fairness of a transaction and the issue of copyright protection after an image is sold.This neglect harms the interests of users and affects their enthusiasm for trading.A secure way to safely transact images is needed.We proposed a copyright-preserving and fair image trading scheme based on blockchain,which combines amplifying locality-sensitive hashing with searchable symmetric encryption to achieve safe image retrieval on blockchain and ensure the credibility of the image retrieval process.Additionally,we use digital fingerprint and watermark technologies to realize the copyright protection of images and use smart contracts to achieve fair transaction processes.The experimental results show that our scheme can protect image copyrights and realize a fair trading process while ensuring efficiency. 展开更多
关键词 blockchain copyright-preserving trade fair trade tadors code
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Aeroacoustic and aerodynamic optimization of propeller blades 被引量:6
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作者 Peixun YU jiahui peng +2 位作者 Junqiang BAI Xiao HAN Xiang SONG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2020年第3期826-839,共14页
It is of great significance to develop a high-efficiency and low-noise propeller optimization method for new-generation propeller aircraft design.Coupled with free form deformation method,dynamic mesh interpolation te... It is of great significance to develop a high-efficiency and low-noise propeller optimization method for new-generation propeller aircraft design.Coupled with free form deformation method,dynamic mesh interpolation technology,optimization algorithm,surrogate model,aerodynamic calculation and aeroacoustic prediction model module,the integrated aerodynamic and aeroacoustic design method of propeller is built.The optimization design for the six-blade propeller is carried out.The non-reduction in efficiency,thrust coefficient and the minimum of aerodynamic noise is treated as the optimization design objective.The spatial vorticity distribution of the propeller before and after the design is also analyzed by using unsteady computational fluid dynamics method.The results show that the optimized propeller can effectively reduce the aerodynamic noise level.The maximum total sound pressure level can be reduced by 5 dB without reducing its aerodynamic performance.The developed method has good application potential in low-noise optimization design of propeller and other rotating machinery. 展开更多
关键词 AEROACOUSTIC Aerodynamic Dynamic mesh interpolation technology Free form deformation method Optimization algorithm PROPELLER Sound pressure level Surrogate model
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