The carrying capacity of marine and land resources is one of the indicators to measure the sustainable development level of coastal areas,reflecting the supporting capacity of the ecological environment for human acti...The carrying capacity of marine and land resources is one of the indicators to measure the sustainable development level of coastal areas,reflecting the supporting capacity of the ecological environment for human activities and the impact of human activities on the regional environment.This paper establishes an evaluation index system to determine the evaluation value of the carrying capacity of marine and land resources in China’s coastal areas,the evaluation index of marine and land resources supply capacity(economic and social development demand)subsystem,and the degree of coordinated development of the subsystems in 11 coastal areas from 2006 to 2017.The results showed that the average supply and demand capacity of the two subsystems in each region is not high;the average demand level of economic and social development is higher than the supply capacity of marine and land resources;the carrying capacity of marine and land resources is slightly overloaded in most areas;the collaborative development between the supply and demand subsystems is barely coordinated with moderate imbalance;most regions need to move in the direction of green development to ensure the supply capacity of marine and land resources.展开更多
Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This ...Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.展开更多
Based on China’s real estate investment(REI), commercial housing sales(CHS), and GDP data from 2001 to 2020, we studied the dependence, asymmetry, and transmission direction of China’s real estate and economy. Their...Based on China’s real estate investment(REI), commercial housing sales(CHS), and GDP data from 2001 to 2020, we studied the dependence, asymmetry, and transmission direction of China’s real estate and economy. Their cross-correlation is demonstrated through the deep crosscorrelation analysis(DCCA) algorithm, multifractal asymmetric detrended cross-correlation analysis(MF-ADCCA) algorithm and DCCA algorithm based on a time delay. Both REI and CHS have persistence with GDP. The real estate industry and economy have asymmetric multifractal characteristics.Meanwhile, real estate and the economy have different trends, and they can affect each other with the same length of time delay. This effect diminishes in a short period of time, and there are unsteady fluctuations in cross-correlation persistence in the long term.展开更多
基金Postdoctoral Research Foundation of Chaoyang District(Q1011019202101)Beijing Postdoctoral Research Foundation(Q6011019202101).
文摘The carrying capacity of marine and land resources is one of the indicators to measure the sustainable development level of coastal areas,reflecting the supporting capacity of the ecological environment for human activities and the impact of human activities on the regional environment.This paper establishes an evaluation index system to determine the evaluation value of the carrying capacity of marine and land resources in China’s coastal areas,the evaluation index of marine and land resources supply capacity(economic and social development demand)subsystem,and the degree of coordinated development of the subsystems in 11 coastal areas from 2006 to 2017.The results showed that the average supply and demand capacity of the two subsystems in each region is not high;the average demand level of economic and social development is higher than the supply capacity of marine and land resources;the carrying capacity of marine and land resources is slightly overloaded in most areas;the collaborative development between the supply and demand subsystems is barely coordinated with moderate imbalance;most regions need to move in the direction of green development to ensure the supply capacity of marine and land resources.
基金supported by the National Natural Science Foundation of China(81270897,81300668,81370939,81400813,81400808,81530026,81370922)the Jiangsu Provincial Special Program of Medical Science(BL2012026)the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions support this study
文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.
基金Supported by Postdoctoral Research Foundation of Chaoyang District (Q1011019202101)Beijing Postdoctoral Research Foundation (Q6011019202101)Special Project for Soft Science Research of Hebei Provincial Science and Technology Plan (215576107D)。
文摘Based on China’s real estate investment(REI), commercial housing sales(CHS), and GDP data from 2001 to 2020, we studied the dependence, asymmetry, and transmission direction of China’s real estate and economy. Their cross-correlation is demonstrated through the deep crosscorrelation analysis(DCCA) algorithm, multifractal asymmetric detrended cross-correlation analysis(MF-ADCCA) algorithm and DCCA algorithm based on a time delay. Both REI and CHS have persistence with GDP. The real estate industry and economy have asymmetric multifractal characteristics.Meanwhile, real estate and the economy have different trends, and they can affect each other with the same length of time delay. This effect diminishes in a short period of time, and there are unsteady fluctuations in cross-correlation persistence in the long term.
