10, 11-Dihydro-10-hydroxycyproheptadine was synthesized in a new and facile synthetic route and resolved by L-（-）-2-（1, 3）-dioxo-1, 3-dihydroisoindol-2-yl）-propionic acid and D-（＋）-tartaric acid, respectively....10, 11-Dihydro-10-hydroxycyproheptadine was synthesized in a new and facile synthetic route and resolved by L-（-）-2-（1, 3）-dioxo-1, 3-dihydroisoindol-2-yl）-propionic acid and D-（＋）-tartaric acid, respectively. The free base of the two enantiomers has the same absolute specific rotation value.展开更多
文摘10, 11-Dihydro-10-hydroxycyproheptadine was synthesized in a new and facile synthetic route and resolved by L-（-）-2-（1, 3）-dioxo-1, 3-dihydroisoindol-2-yl）-propionic acid and D-（＋）-tartaric acid, respectively. The free base of the two enantiomers has the same absolute specific rotation value.
