Jointly hosted by Wuhan University of Technology,Changsha University and Kent State University,the 3rd International Workshop on Graphene and C3N4-based Photocatalysts(IWGCP3)was held at Wuhan University of Technology...Jointly hosted by Wuhan University of Technology,Changsha University and Kent State University,the 3rd International Workshop on Graphene and C3N4-based Photocatalysts(IWGCP3)was held at Wuhan University of Technology,Wuhan,China on March 23-26,2019.This workshop was sponsored by National Natural Science Foundation of China(NSFC),Wuhan University of Technology,Changsha University,Beijing Perfectlight and others.Over 300 colleagues from all over the world participated in this workshop,which featured 8 plenary lectures,12 keynote lectures,22 invited lectures,13 oral lectures and 157 posters.Top ten posters enjoyed recognition by the scientific committee during the workshop.展开更多
The development of high-efficiency peroxidase mimetics is highly desirable in view of high cost and low stability of natural enzymes.From the perspective of mimicking active site microenvironment at low cost,we herein...The development of high-efficiency peroxidase mimetics is highly desirable in view of high cost and low stability of natural enzymes.From the perspective of mimicking active site microenvironment at low cost,we herein report a novel histidine-functionalized graphene quantum dot(His-GQD)/hemin complex,which exhibits the highest catalytic rate for the peroxidase-based chromogenic reaction among the hemin-containing mimetics reported so far.Also,our peroxidase mimetic shows excellent tolerance to strongly acidic conditions and can function in a wide temperature range.Lineweaver-Burk plots and comprehensive electron paramagnetic resonance analysis reveal a ping-pong type catalytic mechanism for this mimetic.In addition,His-GQD/hemin demonstrates high efficiency and accuracy in detecting H2O2 and blood glucose.Our work provides an effective design of artificial enzymes for practical applications.展开更多
基金financially supported by NSFC (U1705251 and 21433007)
文摘Jointly hosted by Wuhan University of Technology,Changsha University and Kent State University,the 3rd International Workshop on Graphene and C3N4-based Photocatalysts(IWGCP3)was held at Wuhan University of Technology,Wuhan,China on March 23-26,2019.This workshop was sponsored by National Natural Science Foundation of China(NSFC),Wuhan University of Technology,Changsha University,Beijing Perfectlight and others.Over 300 colleagues from all over the world participated in this workshop,which featured 8 plenary lectures,12 keynote lectures,22 invited lectures,13 oral lectures and 157 posters.Top ten posters enjoyed recognition by the scientific committee during the workshop.
基金The authors acknowledge financial support for this work from the National Key R&D Program"nanotechnology"special focus(No.2016YFA0201600)the National Natural Science Foundation of China(Nos.21422303,21573049,21872043,81602643)+1 种基金Beijing Natural Science Foundation(No.2142036)the Knowledge Innovation Program,Youth Innovation Promotion Association,and Special Program of"One Belt One Road"of CAS.The authors thank Dr.Dexing Li for the technique support and many helpful discussions for the ITC testing.
文摘The development of high-efficiency peroxidase mimetics is highly desirable in view of high cost and low stability of natural enzymes.From the perspective of mimicking active site microenvironment at low cost,we herein report a novel histidine-functionalized graphene quantum dot(His-GQD)/hemin complex,which exhibits the highest catalytic rate for the peroxidase-based chromogenic reaction among the hemin-containing mimetics reported so far.Also,our peroxidase mimetic shows excellent tolerance to strongly acidic conditions and can function in a wide temperature range.Lineweaver-Burk plots and comprehensive electron paramagnetic resonance analysis reveal a ping-pong type catalytic mechanism for this mimetic.In addition,His-GQD/hemin demonstrates high efficiency and accuracy in detecting H2O2 and blood glucose.Our work provides an effective design of artificial enzymes for practical applications.
