The binding of coordination compound Ru(phen) to calf thymus DNA andherring Aparm DNA has been investigated by absorption,emission and of circulardichroism,spectroscopy. Measurement ot enantioselectivily combvined w...The binding of coordination compound Ru(phen) to calf thymus DNA andherring Aparm DNA has been investigated by absorption,emission and of circulardichroism,spectroscopy. Measurement ot enantioselectivily combvined with photophysical experiment shows the bindins of Ru(phen),with calf thymus DNA is ofintercaiatively bound .mode but the binding of Ru(Phen),with herring spermDNA is of surface-bound mode.展开更多
Two new ruthenium polypyridine complexes. L2RuL2+ where L=2,2'-bipyridine (bpy) and 2, 9-dimethyl-1. 10-phenanthroline (dmp); L' is Schiff base prepared from condensation of 4. 5 diazafluoren-9-one (AFO) and a...Two new ruthenium polypyridine complexes. L2RuL2+ where L=2,2'-bipyridine (bpy) and 2, 9-dimethyl-1. 10-phenanthroline (dmp); L' is Schiff base prepared from condensation of 4. 5 diazafluoren-9-one (AFO) and aniline. have been prepared and characterized by elemental analyses, electronic absorption, IR spectra. The binding of the complexes to calf thymus DNA has beeninvestics by absorption. emission spectra and circular dichroism spectroscopy. Experimental results show these two complexes bind to DNA by electrostatic mode and non-interactive binding mode.展开更多
Two new polypyridine ligands. imidazo[f] 1, 10-phenanthroline(IP)and 2-phenyl-imidazo[f]1,10-phenanthroline (PIF) and their Ru (Ⅱ)mixedtype coordination compounds together with 2,2'-bipyridine(bpy)and1, 10-phenan...Two new polypyridine ligands. imidazo[f] 1, 10-phenanthroline(IP)and 2-phenyl-imidazo[f]1,10-phenanthroline (PIF) and their Ru (Ⅱ)mixedtype coordination compounds together with 2,2'-bipyridine(bpy)and1, 10-phenanthroline(phen)are synthesised and charaeterized by elementalanalyses meltion points ,electronic absorption,IR,emission spectra and eyclic voltammetry.展开更多
The binding of [Ru(bpy)2(IP)]2+(b2IP),[Ru(bpy)2(PIP)]2+(b2PIP),[Ru(Phen)2 (IP)]2+(p2IP),[Ru(phen)2(PIP)]2+(p2PIP) to calf thymus DNA was investigated using electronic absorption, circular dichroism and fluorescence em...The binding of [Ru(bpy)2(IP)]2+(b2IP),[Ru(bpy)2(PIP)]2+(b2PIP),[Ru(Phen)2 (IP)]2+(p2IP),[Ru(phen)2(PIP)]2+(p2PIP) to calf thymus DNA was investigated using electronic absorption, circular dichroism and fluorescence emission spectroscopies.CD spectra of dialyzates indicate enantioselectivity associated with binding.Evidence of intercalative binding is also provided by hypochromicity in the MLCT bands, increased emission intensities and curvature of emission quenching by [Fe (CN)6]4-. The total binding affinities seem to be in the order b2IP<b2PIP≤p2IP<p2PIP, which is consistent, with the order of ligand planarity. extent of aromtic πsystem and hydrophobicity, bpy<<phen<IP<PIP.展开更多
文摘The binding of coordination compound Ru(phen) to calf thymus DNA andherring Aparm DNA has been investigated by absorption,emission and of circulardichroism,spectroscopy. Measurement ot enantioselectivily combvined with photophysical experiment shows the bindins of Ru(phen),with calf thymus DNA is ofintercaiatively bound .mode but the binding of Ru(Phen),with herring spermDNA is of surface-bound mode.
文摘Two new ruthenium polypyridine complexes. L2RuL2+ where L=2,2'-bipyridine (bpy) and 2, 9-dimethyl-1. 10-phenanthroline (dmp); L' is Schiff base prepared from condensation of 4. 5 diazafluoren-9-one (AFO) and aniline. have been prepared and characterized by elemental analyses, electronic absorption, IR spectra. The binding of the complexes to calf thymus DNA has beeninvestics by absorption. emission spectra and circular dichroism spectroscopy. Experimental results show these two complexes bind to DNA by electrostatic mode and non-interactive binding mode.
文摘Two new polypyridine ligands. imidazo[f] 1, 10-phenanthroline(IP)and 2-phenyl-imidazo[f]1,10-phenanthroline (PIF) and their Ru (Ⅱ)mixedtype coordination compounds together with 2,2'-bipyridine(bpy)and1, 10-phenanthroline(phen)are synthesised and charaeterized by elementalanalyses meltion points ,electronic absorption,IR,emission spectra and eyclic voltammetry.
文摘The binding of [Ru(bpy)2(IP)]2+(b2IP),[Ru(bpy)2(PIP)]2+(b2PIP),[Ru(Phen)2 (IP)]2+(p2IP),[Ru(phen)2(PIP)]2+(p2PIP) to calf thymus DNA was investigated using electronic absorption, circular dichroism and fluorescence emission spectroscopies.CD spectra of dialyzates indicate enantioselectivity associated with binding.Evidence of intercalative binding is also provided by hypochromicity in the MLCT bands, increased emission intensities and curvature of emission quenching by [Fe (CN)6]4-. The total binding affinities seem to be in the order b2IP<b2PIP≤p2IP<p2PIP, which is consistent, with the order of ligand planarity. extent of aromtic πsystem and hydrophobicity, bpy<<phen<IP<PIP.
