This work started out with the in-depth feasibil-ity study and limitation analysis on the current disease spread estimating and countermea-sures evaluating models, then we identify that the population variability is a...This work started out with the in-depth feasibil-ity study and limitation analysis on the current disease spread estimating and countermea-sures evaluating models, then we identify that the population variability is a crucial impact which has been always ignored or less empha-sized. Taking HIV/AIDS as the application and validation background, we propose a novel al-gorithm model system, EEA model system, a new way to estimate the spread situation, evaluate different countermeasures and analyze the development of ARV-resistant disease strains. The model is a series of solvable ordi-nary differential equation (ODE) models to es-timate the spread of HIV/AIDS infections, which not only require only one year’s data to deduce the situation in any year, but also apply the piecewise constant method to employ multi- year information at the same time. We simulate the effects of therapy and vaccine, then evaluate the difference between them, and offer the smallest proportion of the vaccination in the population to defeat HIV/AIDS, especially the advantage of using the vaccination while the deficiency of using therapy separately. Then we analyze the development of ARV-resistant dis-ease strains by the piecewise constant method. Last but not least, high performance computing (HPC) platform is applied to simulate the situa-tion with variable large scale areas divided by grids, and especially the acceleration rate will come to around 4 to 5.5.展开更多
The aim of this paper is to propose a theoretical approach for performing the nonprobabilistic reliability analysis of structure.Due to a great deal of uncertainties and limited measured data in engineering practice,t...The aim of this paper is to propose a theoretical approach for performing the nonprobabilistic reliability analysis of structure.Due to a great deal of uncertainties and limited measured data in engineering practice,the structural uncertain parameters were described as interval variables.The theoretical analysis model was developed by starting from the 2-D plane and 3-D space.In order to avoid the loss of probable failure points,the 2-D plane and 3-D space were respectively divided into two parts and three parts for further analysis.The study pointed out that the probable failure points only existed among extreme points and root points of the limit state function.Furthermore,the low-dimensional analytical scheme was extended to the high-dimensional case.Using the proposed approach,it is easy to find the most probable failure point and to acquire the reliability index through simple comparison directly.A number of equations used for calculating the extreme points and root points were also evaluated.This result was useful to avoid the loss of probable failure points and meaningful for optimizing searches in the research field.Finally,two kinds of examples were presented and compared with the existing computation.The good agreements show that the proposed theoretical analysis approach in the paper is correct.The efforts were conducted to improve the optimization method,to indicate the search direction and path,and to avoid only searching the local optimal solution which would result in missed probable failure points.展开更多
Recently,analyzing big data on the move is booming.It requires that the hardware resource should be low volume,low power,light in weight,high-performance,and highly scalable whereas the management software should be f...Recently,analyzing big data on the move is booming.It requires that the hardware resource should be low volume,low power,light in weight,high-performance,and highly scalable whereas the management software should be flexible and consume little hardware resource.To meet these requirements,we present a system named SOCA-DOM that encompasses a mobile system-on-chip array architecture and a two-tier“software-defined”resource manager named Chameleon.First,we design an Ethernet communication board to support an array of mobile system-on-chips.Second,we propose a two-tier software architecture for Chameleon to make it flexible.Third,we devise data,configuration,and control planes for Chameleon to make it“software-defined”and in turn consume hardware resources on demand.Fourth,we design an accurate synthetic metric that represents the computational power of a computing node.We employ 12 Apache Spark benchmarks to evaluate SOCA-DOM.Surprisingly,SOCA-DOM consumes up to 9.4x less CPU resources and 13.5x less memory than Mesos which is an existing resource manager.In addition,we show that a 16-node SOCA-DOM consumes up to 4x less energy than two standard Xeon servers.Based on the results,we conclude that an array architecture with fine-grained hardware resources and a software-defined resource manager works well for analyzing big data on the move.展开更多
文摘This work started out with the in-depth feasibil-ity study and limitation analysis on the current disease spread estimating and countermea-sures evaluating models, then we identify that the population variability is a crucial impact which has been always ignored or less empha-sized. Taking HIV/AIDS as the application and validation background, we propose a novel al-gorithm model system, EEA model system, a new way to estimate the spread situation, evaluate different countermeasures and analyze the development of ARV-resistant disease strains. The model is a series of solvable ordi-nary differential equation (ODE) models to es-timate the spread of HIV/AIDS infections, which not only require only one year’s data to deduce the situation in any year, but also apply the piecewise constant method to employ multi- year information at the same time. We simulate the effects of therapy and vaccine, then evaluate the difference between them, and offer the smallest proportion of the vaccination in the population to defeat HIV/AIDS, especially the advantage of using the vaccination while the deficiency of using therapy separately. Then we analyze the development of ARV-resistant dis-ease strains by the piecewise constant method. Last but not least, high performance computing (HPC) platform is applied to simulate the situa-tion with variable large scale areas divided by grids, and especially the acceleration rate will come to around 4 to 5.5.
基金the National Natural Science Foundation of China (51408444, 51708428)
文摘The aim of this paper is to propose a theoretical approach for performing the nonprobabilistic reliability analysis of structure.Due to a great deal of uncertainties and limited measured data in engineering practice,the structural uncertain parameters were described as interval variables.The theoretical analysis model was developed by starting from the 2-D plane and 3-D space.In order to avoid the loss of probable failure points,the 2-D plane and 3-D space were respectively divided into two parts and three parts for further analysis.The study pointed out that the probable failure points only existed among extreme points and root points of the limit state function.Furthermore,the low-dimensional analytical scheme was extended to the high-dimensional case.Using the proposed approach,it is easy to find the most probable failure point and to acquire the reliability index through simple comparison directly.A number of equations used for calculating the extreme points and root points were also evaluated.This result was useful to avoid the loss of probable failure points and meaningful for optimizing searches in the research field.Finally,two kinds of examples were presented and compared with the existing computation.The good agreements show that the proposed theoretical analysis approach in the paper is correct.The efforts were conducted to improve the optimization method,to indicate the search direction and path,and to avoid only searching the local optimal solution which would result in missed probable failure points.
基金the Key Research and Development Program of Guangdong Province of China under Grant No.2019B010155003the National Natural Science Foundation of China under Grant Nos.61672511,61702495,and 61802384the Shenzhen Institute of Artificial Intelligence and Robotics for Society,The Chinese University of Hong Kong,Shenzhen,and the Alibaba Innovative Research Project for Large-Scale Graph Pattern Discovery,Analysis,and Query Techniques.
文摘Recently,analyzing big data on the move is booming.It requires that the hardware resource should be low volume,low power,light in weight,high-performance,and highly scalable whereas the management software should be flexible and consume little hardware resource.To meet these requirements,we present a system named SOCA-DOM that encompasses a mobile system-on-chip array architecture and a two-tier“software-defined”resource manager named Chameleon.First,we design an Ethernet communication board to support an array of mobile system-on-chips.Second,we propose a two-tier software architecture for Chameleon to make it flexible.Third,we devise data,configuration,and control planes for Chameleon to make it“software-defined”and in turn consume hardware resources on demand.Fourth,we design an accurate synthetic metric that represents the computational power of a computing node.We employ 12 Apache Spark benchmarks to evaluate SOCA-DOM.Surprisingly,SOCA-DOM consumes up to 9.4x less CPU resources and 13.5x less memory than Mesos which is an existing resource manager.In addition,we show that a 16-node SOCA-DOM consumes up to 4x less energy than two standard Xeon servers.Based on the results,we conclude that an array architecture with fine-grained hardware resources and a software-defined resource manager works well for analyzing big data on the move.