Influencing factors of postoperative early delayed gastric emptying after minimally invasive Ivor-Lewis esophagectomy

BACKGROUND The main clinical treatment for esophageal cancer is surgery. Since traditional open esophageal cancer resection has the disadvantages of large trauma, long recovery period, and high postoperative complication rate, its clinical application is gradually reduced. The current report of minimally invasive Ivor-Lewis esophagectomy(MIILE) is increasing. However, researchers found that patients with MIILE had a higher incidence of early delayed gastric emptying(DGE).AIM To investigate the influencing factors of postoperative early DGE after MIILE.METHODS A total of 156 patients diagnosed with esophageal cancer at Deyang People's Hospital were enrolled. According to the criteria of DGE, patients were assigned to a DGE group(n = 49) and a control group(n = 107). The differences between the DGE group and the control group were compared. Multivariate logistic regression analysis was used to further determine the influencing factors of postoperative early DGE. The receiver operating characteristic(ROC) curve was used to assess potential factors in predicting postoperative early DGE.RESULTS Age, intraoperative blood loss, chest drainage time, portion of anxiety score ≥ 45 points, analgesia pump use, postoperative to enteral nutrition interval, and postoperative fluid volume in the DGE group were higher than those in the control group. Perioperative albumin level in the DGE group was lower than that in the control group(P < 0.05). Age, anxiety score, perioperative albumin level,and postoperative fluid volume were independent factors influencing postoperative early DGE, and the differences were statistically significant(P <0.05). The ROC curve analysis revealed that the area under the curve(AUC) foranxiety score was 0.720. The optimum cut-off value was 39, and the sensitivity and specificity were 80.37% and 65.31%, respectively. The AUC for postoperative fluid volume were 0.774. The optimal cut-off value was 1191.86 mL, and the sensitivity and specificity were 65.3% and 77.6%, respectively. The AUC for perioperative albumin level was 0.758. The optimum cut-off value was 26.75 g/L,and the sensitivity and specificity were 97.2% and 46.9%, respectively.CONCLUSION Advanced age, postoperative anxiety, perioperative albumin level, and postoperative fluid volume can increase the incidence of postoperative early DGE.

Research on hypertension in hohhot of mongolian: analysis of 9675 cases survey data

Objective: Through investigating the daily habits of hypertensive and non-hypertensive Mongolian in Hohhot to explore the effect of daily habits on hypertension and further provide basis for future policy making. Methods: Two community health service centers were identified in each of the four districts of Hohhot City using a stratified cluster random sampling method and a multi-stage stratified sampling method. Results: By January 2019, a total of 9,800 people was investigated, and 9675 people with complete data. The effective rate of the questionnaire was 98.7%. The standardized prevalence of hypertension was 21.8% in Mongolia. The prevalence rate of hypertension in Mongolia was statistically significant among the different genders, ages, presence or absence of obesity, different diet types, whether smoking or drinking, or having tea, and aerobic exercise.(P < 0.05 for all). Multivariate unconditional logistic regression analysis showed that males were risk factors for hypertension;female, non-obese, non-hobby meat, no smoking, hobby tea, no alcohol and aerobic exercise were protective factors. Obesity, hobbies, meat, smoking, drinking are important risk factors for hypertension in Mongolian population in Hohhot. Conclusion: It is preliminarily clarified that the risk factors related to hypertension are mainly related to their own health-related behaviors and genetic factors, suggesting the necessity of healthy physical examination, maintaining blood pressure stability, controlling body mass, and moderate exercise.

Application of geophysical methods in fine detection of urban concealed karst:A case study of Wuhan City,China

The construction of modern livable cities faces challenges in karst areas,including ground collapse and engineering problems.Wuhan,with a population of 13.74×10^(6) and approximately 1161 km^(2)of soluble rocks in the urban area of 8569.15 km^(2),predominantly consists of concealed karst areas where occasional ground collapse events occur,posing significant threats to underground engineering projects.To address these challenges,a comprehensive geological survey was conducted in Wuhan,focusing on major karstrelated issues.Geophysical methods offer advantages over drilling in detecting concealed karst areas due to their efficiency,non-destructiveness,and flexibility.This paper reviewed the karst geological characteristics in Wuhan and the geophysical exploration methods for karst,selected eight effective geophysical methods for field experimentation,evaluated their suitability,and proposed method combinations for different karst scenarios.The results show that different geophysical methods have varying applicability for karst detection in Wuhan,and combining multiple methods enhances detection effectiveness.The specific recommendations for method combinations provided in this study serve as a valuable reference for karst detection in Wuhan.

Juvenile dermatomyositis:advances in clinical presentation,myositis-specific antibodies and treatment

Background Juvenile dermatomyositis(JDM)is a chronic autoimmune disease characteristic by inflammation of small vessels within the skin,muscle and vital organs.But the clinical features and treatment of JDM have not been fully clarified.Data sources Databases underwent through PubMed for articles about the clinical features,myositis-specific antibodiesof JDM and its treatment,and we selected publications written in English which were relevant to the topic of this review.Results Clinical features and myositis-specific antibodies may predict the severity and prognosis of disease.Although the mortality rate has been lower with traditional treatments,such as corticosteroid,intravenous immunoglobulin,and diseasemodifying anti-rheumatic drugs such as methotrexate,their usages are variable.Novel biological therapies seem to be effective for refractory JDM patients,but more clinical trials are necessary.Conclusions JDM is a sever disease of childhood.We need to better understand recent advances of JDM in the context of clinical features including skin manifestations,muscle weakness and organ damage,myositis-specific antibodies and their associated outcomes and the treatment of disease.