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代谢综合征相关指标对老年人前列腺的影响 被引量:3
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作者 杨刚华 张剑琴 +1 位作者 马茂 盛斌武 《中国现代医学杂志》 CAS 2020年第1期93-97,共5页
目的探讨代谢综合征(MS)相关指标对血清前列腺特异性抗原(PSA)、前列腺特异性抗原密度(PSAD)和前列腺体积(PV)的影响。方法收集2011年8月-2017年7月西安交通大学第一附属医院体检中心进行健康查体的4 404例60~95岁男性资料,询问病史,通... 目的探讨代谢综合征(MS)相关指标对血清前列腺特异性抗原(PSA)、前列腺特异性抗原密度(PSAD)和前列腺体积(PV)的影响。方法收集2011年8月-2017年7月西安交通大学第一附属医院体检中心进行健康查体的4 404例60~95岁男性资料,询问病史,通过直肠指检、超声排除前列腺癌,测量人群收缩压(SBP)、舒张压(DBP)、体重(W)、身高(H)、腰围(WC)、体重指数(BMI)。生化分析包括晨空腹血浆葡萄糖(FPG)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血清PSA、尿常规分析等。结果 MS相关指标SBP、TG、HDL-C、LDL-C与血清PSA呈正相关(r=0.084、0.065、0.111和0.080,P<0.05),DBP、TC与血清PSA呈负相关(r=-0.079和-0.083,P<0.05);FPG、LDL-C与PV呈正相关(r=0.112和0.033,P<0.05);BMI、SBP、TG、HDL-C、LDL-C与PSAD呈正相关(r=0.039、0.087、0.059、0.098和0.073,P<0.05),WC、DBP、FPG、TC与PSAD呈负相关(r=-0.039、-0.081、-0.063和-0.074,P<0.05)。进一步行多元线性回归分析发现,MS影响血清PSA、PSAD水平的主要因素为SBP、DBP和HDL(P<0.05),影响PV水平的主要因素为FPG(P<0.05)。结论老年MS患者血清PSA、PSAD水平下降,PV增加。其中血压变化与血清PSA水平密切相关,血糖变化与PV相关。 展开更多
关键词 代谢综合征 前列腺特异性抗原/抗原 人血小板 前列腺体积/前列腺
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ADS Injector-I 2 K superfluid helium cryogenic system 被引量:6
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作者 Rui Ge Shao-Peng Li +14 位作者 Rui-Xiong Han Miao-Fu Xu Liang-Rui Sun Min-Jing Sang Rui Ye Zhuo zhang Jie-Hao zhang Xiang-Zhen zhang Lin Bian jian-qin zhang Mei Li Chang-Cheng Ma Zheng-Ze Chang Tong-Xian Zhao Yong-Cheng Jiang 《Nuclear Science and Techniques》 SCIE CAS CSCD 2020年第4期79-92,共14页
The Accelerator Driven Sub-critical(ADS)system is a strategic plan to solve the nuclear waste problem for nuclear power plants in China.High-energy particle accelerators and colliders contain long strings of supercond... The Accelerator Driven Sub-critical(ADS)system is a strategic plan to solve the nuclear waste problem for nuclear power plants in China.High-energy particle accelerators and colliders contain long strings of superconducting devices,superconducting radio frequency cavities,and magnets,which may require cooling by 2 K superfluid helium(HeliumⅡ).2 K superfluid helium cryogenic system has become a research hot spot in the field of superconducting accelerators.In this study,the ADS Injector-I 2 K cryogenic system is examined in detail.The cryogenic system scheme design,key equipment,and technology design,such as the 2 K Joule–Thomson(J–T)heat exchanger and cryomodules CM1+CM2 design,are examined,in addition to the commissioning and operation of the cryogenic system.The ADS Injector-I 2 K cryogenic system is the first 100 W superfluid helium system designed and built independently in China.The ADS proton beam reached 10 Me V at 10 m A in July 2016 and 10 Me V at 2 m A in continuous mode in January 2017 and has been operated reliably for over 15,000 h,proving that the design of ADS Injector-I 2 K cryogenic system,the key equipment,and technology research are reasonable,reliable,and meet the requirements.The research into key technologies provides valuable engineering experience that can be helpful for future projects such as CI-ADS(China Initiative Accelerator-Driven System),SHINE(Shanghai High Repetition Rate XFEL and Extreme Light Facility),PAPS(Platform of Advanced Photon Source Technology),and CEPC(Circular Electron-Positron Collider),thereby developing national expertise in the field of superfluid helium cryogenic systems. 展开更多
关键词 ADS SUPERFLUID HELIUM CRYOGENIC system Cryomodule J–T heat EXCHANGER
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Increased life-span of Drosophila melanogaster by Flavonoids from Scutellariabaicalensis Georgi induced by hydrogen peroxide
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作者 Dan-Dan Duan Li Gao +3 位作者 Xue-Ling zhang jian-qin zhang Xue-Mei Qin Guan-Hua Du 《TMR Integrative Medicine》 2017年第3期79-85,共7页
目的:探讨黄芩中黄酮类化合物在过氧化氢(H2O2)诱导黑腹果蝇模型中的作用及机制.方法:采用H2O2诱导黑腹果蝇衰老模型,研究黄芩中黄酮化合物的作用.其次,研究了黄芩素和汉黄芩素对mRNA表达的影响.结果:黄芩素和汉黄芩素能够通过增... 目的:探讨黄芩中黄酮类化合物在过氧化氢(H2O2)诱导黑腹果蝇模型中的作用及机制.方法:采用H2O2诱导黑腹果蝇衰老模型,研究黄芩中黄酮化合物的作用.其次,研究了黄芩素和汉黄芩素对mRNA表达的影响.结果:黄芩素和汉黄芩素能够通过增加超氧化物歧化酶(SOD),过氧化氢酶(CAT)和玫瑰红(RY)mRNA的表达,延长H2O2诱导果蝇老化模型的寿命.结论:黄芩素和汉黄芩素可能通过上调SOD,CAT和RYmRNA的表达,延长H2O2诱导的果蝇老化模型的寿命. 展开更多
关键词 黄芩素 汉黄芩素 寿命 过氧化氢 黑腹果蝇
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Testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children aged<3 years:10-year experience with 1034 cases 被引量:3
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作者 Liu Chen Wen-Hua Huang +4 位作者 Yun-Jin Wang Qi-Liang zhang Chao-Ming Zhou Xu Cui jian-qin zhang 《Asian Journal of Andrology》 SCIE CAS CSCD 2020年第6期649-652,共4页
This study was performed to summarize our clinical experience with testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children.This study included 1034 chi... This study was performed to summarize our clinical experience with testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children.This study included 1034 children with palpable cryptorchidism from March 2009 to March 2019.A scrotal stria incision was used to perform testicular descent and fixation.Overall,1020 children successfully underwent surgical testicular descent and fixation through a scrotal stria incision,and 14 patients underwent conversion to inguinal incision surgery.All patients were discharged 1-2 days after the operation.During hospitalization and follow-up,55 patients developed complicationsy including 10 patients with testicular retraction,7 with poor healing of the incision,and 38 with a scrotal hematoma.No patients developed testicular atrophy,an in direct ingui nal hernia,or a hydrocoele.Testicular descent and fixation through a scrotal stria incision for the treatment of palpable cryptorchidism in children is safe and feasible in well-selected cases.This method has the advantages of no scarring and a good cosmetic effect. 展开更多
关键词 CHILDREN cosmetic effect palpable cryptorchidism scrotal stria incision testicular descending fixation
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