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The Solar Upper Transition Region Imager(SUTRI)Onboard the SATech-01 Satellite 被引量:3
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作者 Xianyong Bai Hui Tian +56 位作者 Yuanyong Deng Zhanshan Wang jianfeng yang Xiaofeng Zhang Yonghe Zhang Runze Qi Nange Wang yang Gao Jun Yu Chunling He Zhengxiang Shen Lun Shen Song Guo Zhenyong Hou Kaifan Ji Xingzi Bi Wei Duan Xiao yang Jiaben Lin Ziyao Hu Qian Song Zihao yang Yajie Chen Weidong Qiao Wei Ge Fu Li Lei Jin Jiawei He Xiaobo Chen Xiaocheng Zhu Junwang He Qi Shi Liu Liu Jinsong Li Dongxiao Xu Rui Liu Taijie Li Zhenggong Feng Yamin Wang Chengcheng Fan Shuo Liu Sifan Guo Zheng Sun Yuchuan Wu Haiyu Li Qi yang Yuyang Ye Weichen Gu Jiali Wu Zhe Zhang Yue Yu Zeyi Ye Pengfeng Sheng Yifan Wang Wenbin Li Qiushi Huang Zhong Zhang 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2023年第6期153-171,共19页
The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the... The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections. 展开更多
关键词 Sun:transition region Sun:UV radiation Sun:activity space vehicles:instruments
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Recent Advances of Deep Learning in Geological Hazard Forecasting 被引量:2
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作者 Jiaqi Wang Pengfei Sun +3 位作者 Leilei Chen jianfeng yang Zhenghe Liu Haojie Lian 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第11期1381-1418,共38页
Geological hazard is an adverse geological condition that can cause loss of life and property.Accurate prediction and analysis of geological hazards is an important and challenging task.In the past decade,there has be... Geological hazard is an adverse geological condition that can cause loss of life and property.Accurate prediction and analysis of geological hazards is an important and challenging task.In the past decade,there has been a great expansion of geohazard detection data and advancement in data-driven simulation techniques.In particular,great efforts have been made in applying deep learning to predict geohazards.To understand the recent progress in this field,this paper provides an overview of the commonly used data sources and deep neural networks in the prediction of a variety of geological hazards. 展开更多
关键词 Geological hazard deep learning neural networks geohazard data sources EARTHQUAKE VOLCANIC
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An OP-TEE Energy-Efficient Task Scheduling Approach Based on Mobile Application Characteristics
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作者 Hai Wang Xuan Hao +3 位作者 Shuo Ji Jie Zheng Yuhui Ma jianfeng yang 《Intelligent Automation & Soft Computing》 SCIE 2023年第8期1621-1635,共15页
Trusted Execution Environment(TEE)is an important part of the security architecture of modern mobile devices,but its secure interaction process brings extra computing burden to mobile devices.This paper takes open por... Trusted Execution Environment(TEE)is an important part of the security architecture of modern mobile devices,but its secure interaction process brings extra computing burden to mobile devices.This paper takes open portable trusted execution environment(OP-TEE)as the research object and deploys it to Raspberry Pi 3B,designs and implements a benchmark for OP-TEE,and analyzes its program characteristics.Furthermore,the application execution time,energy consumption and energy-delay product(EDP)are taken as the optimization objectives,and the central processing unit(CPU)frequency scheduling strategy of mobile devices is dynamically adjusted according to the characteristics of different applications through the combined model.The experimental result shows that compared with the default strategy,the scheduling method proposed in this paper saves 21.18%on average with the Line Regression-Decision Tree scheduling model with the shortest delay as the optimization objective.The Decision Tree-Support Vector Regression(SVR)scheduling model,which takes the lowest energy consumption as the optimization goal,saves 22%energy on average.The Decision Tree-K-Nearest Neighbor(KNN)scheduling model with the lowest EDP as the optimization objective optimizes about 33.9%on average. 展开更多
关键词 Trusted execution environment energy efficiency optimization CPU scheduling governor machine learning
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Acid Soil Is Associated with Reduced Yield, Root Growth and Nutrient Uptake in Black Pepper (<i>Piper nigrum</i>L.) 被引量:9
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作者 Chao Zu Zhigang Li +5 位作者 jianfeng yang Huan Yu Yan Sun Hongliang Tang Russell Yost Huasong Wu 《Agricultural Sciences》 2014年第5期466-473,共8页
Low pH is a major limiting factor for the production of black pepper (Piper nigrum L.) in Hainan province. Black pepper gardens often exhibit a decrease in soil pH (to 5.5 - 5.0) on orchards with a multi-year producti... Low pH is a major limiting factor for the production of black pepper (Piper nigrum L.) in Hainan province. Black pepper gardens often exhibit a decrease in soil pH (to 5.5 - 5.0) on orchards with a multi-year production history. An exploratory hydroponic experiment was conducted to examine the effects of increasingly acid nutrient solution pH (7.0, 5.5, 4.0, and 3.5) on seedling growth, tissue nutrient concentrations and root morphological traits. The results indicated that low pH may directly inhibit root development and function, limit K, Ca and Mg absorption and reduce seedling growth. At pH 5.5, black pepper attained maximum growth, while the minimum growth occurred at pH 3.5. It can be concluded that low pH reduces plant growth and is associated with low root nutrient concentrations of Ca and Mg, which may explain the decline of the yield in the seven pepper gardens of the Institute. 展开更多
关键词 Nutrient Concentration PEPPER SEEDLING Growth pH Root Morphology Soil ACIDIFICATION
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Numerical modeling of metamorphic core complex formation:Implications for the destruction of the North China Craton 被引量:2
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作者 ZiQi Ma Gang Lu +1 位作者 jianfeng yang Liang Zhao 《Earth and Planetary Physics》 EI CSCD 2022年第2期191-203,共13页
Widespread magmatism, metamorphic core complexes(MCCs), and significant lithospheric thinning occurred during the Mesozoic in the North China Craton(NCC). It has been suggested that the coeval exhumation of MCCs with ... Widespread magmatism, metamorphic core complexes(MCCs), and significant lithospheric thinning occurred during the Mesozoic in the North China Craton(NCC). It has been suggested that the coeval exhumation of MCCs with uniform northwest-southeast shear senses and magmatism probably resulted from a decratonization event during the retreat of the paleo-Pacific Plate. Here we used two-dimensional finite element thermomechanical numerical models to investigate critical parameters controlling the formation of MCCs under far-field extensional stress. We observed three end-member deformation modes: the MCC mode, the symmetric-dome mode, and the pure-shear mode. The MCC mode requires a Moho temperature of ≥700 ℃ and an extensional strain rate of ≥5 × 10^(-16)s^(-1), implying that the lithosphere had already thinned when the MCC was formed in the Mesozoic. Considering that the widespread MCCs have the same northwest-southeast extension direction in the NCC, we suggest that the MCCs are surface expressions of both large-scale extension and craton destruction and that rollback of the paleo-Pacific slab might be the common driving force. 展开更多
关键词 metamorphic core complex North China Craton numerical modeling EXTENSION
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Web software reliability modeling with random impulsive shocks 被引量:1
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作者 jianfeng yang Ming Zhao Wensheng Hu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2014年第2期349-356,共8页
As the web-server based business is rapidly developed and popularized, how to evaluate and improve the reliability of web-servers has been extremely important. Although a large num- ber of software reliability growth ... As the web-server based business is rapidly developed and popularized, how to evaluate and improve the reliability of web-servers has been extremely important. Although a large num- ber of software reliability growth models (SRGMs), including those combined with multiple change-points (CPs), have been available, these conventional SRGMs cannot be directly applied to web soft- ware reliability analysis because of the complex web operational profile. To characterize the web operational profile precisely, it should be realized that the workload of a web server is normally non-homogeneous and often observed with the pattern of random impulsive shocks. A web software reliability model with random im- pulsive shocks and its statistical analysis method are developed. In the proposed model, the web server workload is characterized by a geometric Brownian motion process. Based on a real data set from IIS server logs of ICRMS website (www.icrms.cn), the proposed model is demonstrated to be powerful for estimating impulsive shocks and web software reliability. 展开更多
关键词 web software software reliability growth model(SRGM) change-point (CP) impulsive shocks geometric Brown-ian motion.
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The expressions and significance of α-,β-catenins and cyclin D1 in breast cancers 被引量:1
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作者 Liang Zeng Senlin Chen +1 位作者 Zhihong Liu jianfeng yang 《The Chinese-German Journal of Clinical Oncology》 CAS 2008年第6期335-338,共4页
Objective:To study the relationship between expressions of α-,β-catenins and cyclin D1 and the occurrence, infiltration and metastasis of breast cancer. Methods: High sensitive S-P immunohistochemical method was use... Objective:To study the relationship between expressions of α-,β-catenins and cyclin D1 and the occurrence, infiltration and metastasis of breast cancer. Methods: High sensitive S-P immunohistochemical method was used to detect the protein expressions of α-,β-catenins and cyclin D1 in the 60 cases of breast cancer tissues. Results: Abnormal immu-noreactivities of α-and β-catenins were observed in 37 (61.7%) and 42 (70%) cases of breast cancer tissues, respectively. There were 28 cases (46.7%) who showed cyclin D1 overexpression. The abnormal expression rates of α-and β-catenins in infiltrating lobular carcinoma (ILC) were significantly higher than those in infiltrating ductal carcinoma (IDC) (P<0.05), but they had no relations to the extent of differentiation and lymphatic metastasis of breast cancer (P>0.05). The overexpression rate of cyclin D1 was correlated with tumor stage and lymphatic metastasis of breast cancer (P<0.05), but not with histological type and the extent of differentiation (P>0.05). Cyclin D1 overexpression was observed in 57.1% (24/42) of these cases that showed abnormal staining of β-catenin, but only observed in 22.2% (4/18) of these cases with normal membranous staining of β-catenin. There was a significantly positive correlation between the abnormal expression of β-catenin and overexpression of cyclin D1 (rs=0.321, P<0.05). Conclusion: The abnormal expression of β-catenin may play an important role in the genesis of breast cancer by triggering cyclin D1 overexpression in breast cancer. The abnormal expressions of α-and β-catenins are not a key factor in malignant cell metastasis in breast cancer, but may also involve in the progress. 展开更多
关键词 Α-CATENIN Β-CATENIN CYCLIN D1 乳腺癌 基因表达 治疗方法
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Coordinated Control Strategy for Harmonic Compensation of Multiple Active Power Filters 被引量:1
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作者 jianfeng yang Rende Qi +1 位作者 yang Liu Yu Ding 《Energy Engineering》 EI 2022年第2期609-620,共12页
In order to minimize the harmonic distortion rate of the current at the common coupling point,this paper proposes a coordinated allocation strategy of harmonic compensation capacity considering the performance of acti... In order to minimize the harmonic distortion rate of the current at the common coupling point,this paper proposes a coordinated allocation strategy of harmonic compensation capacity considering the performance of active power filters(APF).On the premise of proportional distribution of harmonic compensation capacity,the harmonic compensation rate of each APF is considered,and the harmonic current value of each APF to be compensated is obtained.At the same time,the communication topology is introduced.Each APF takes into account the compensation ability of other APFs.Finally,three APFs with different capacity and performance are configured at the harmonic source to suppress the same harmonic source,and the harmonic distortion rate is reduced to 1.73%.The simulation results show that the strategy can effectively improve the compensation capability of the multiple APF cascaded system to the power grid without increasing the installed capacity. 展开更多
关键词 Active power filter collaborative optimization harmonic compensation rate weighting factor communication topology
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Standardization of Leaf Sampling Technique in Jackfruit Nutrient Status Diagnosis 被引量:1
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作者 Yan Sun jianfeng yang +3 位作者 Hua Wang Chao Zu Lehe Tan Gang Wu 《Agricultural Sciences》 2015年第2期232-237,共6页
In China, little information is known about the nutrient requirements of jackfruits and the traditional nutrient management usually depends on the experience. Therefore, in this study, an attempt was made to standardi... In China, little information is known about the nutrient requirements of jackfruits and the traditional nutrient management usually depends on the experience. Therefore, in this study, an attempt was made to standardize the leaf sampling technique and the suitable range of leaf nutrient concentrations for jackfruit (Artocarpus heterophyllus Lam.) nutrient status diagnosis. The sampling result was affected by canopy height, leaf age and time of sampling. Therefore, the three factors were studied. The results illustrated that the stability in level of nutrient concentrations was in 3 - 6 month-old leaves from the central part of the canopy. The most stable period was from April to May for leaf sampling. It was recommended that the stable intracanopy and stable period of nutrient concentrations could be used as the standards of leaf sampling technique. Based on the leaf sampling technique, the standard of leaf nutrient concentrations was summarized, and could be used as the standard of nutrient suitability evaluation. 展开更多
关键词 JACKFRUIT NUTRIENT STATUS DIAGNOSIS LEAF Sampling Technique STANDARDIZATION
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Description of the Cover Picture
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作者 jianfeng yang Chuangmian Huang +1 位作者 Yuanhang Wang Kai Li 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2018年第2期85-96,共12页
Vibration isolation system(VIS)is usually applied to improve the pointing capability and resolution of a space optical payload.A novel vibration isolator is introduced.The equivalent stiffness model of the isolator is... Vibration isolation system(VIS)is usually applied to improve the pointing capability and resolution of a space optical payload.A novel vibration isolator is introduced.The equivalent stiffness model of the isolator is derived by analyzing its static characteristics.A VIS based on the bipod configuration is developed.Its dynamic model is derived and verified using the finite element method and experiments.Because this isolator contains viscoelastic material’which makes the frequency responsive analysis more difficult’an efficiency analysis approach based on the complex stiffness of viscoelastic material is proposed to calculate the transmissibility of the isolator.Finally’a prototype of the vibration isolator is manufactured and experimental studies are carried out.The experimental results show that the analytical results are in good correspondence with the experimental data and the isolator can effectively attenuate the vibrations for the optical payloads.Keywords:isolator;viscoelastic material;space optical 展开更多
关键词 ISOLATOR VISCOELASTIC material space optical PAYLOAD
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Evolution of energy and metal demand driven by industrial revolutions and its trend analysis
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作者 jianfeng yang Yun Yu +2 位作者 Teng Ma Cuiguang Zhang Quan Wang 《Chinese Journal of Population,Resources and Environment》 2021年第3期256-264,共9页
Industrial revolutions have a profound impact on energy and metal demand.Based on technological improvement,industrial transformation,and changes of energy and metal consumption in the United States,this paper identif... Industrial revolutions have a profound impact on energy and metal demand.Based on technological improvement,industrial transformation,and changes of energy and metal consumption in the United States,this paper identified the evolution characteristics of energy and metal demand driven by industrial revolutions,and analyzed the trends of energy and metal demand driven by the fourth industrial revolution which is happening currently.Results indicated that fossil fuels were the major energy sources which boosted up the past three industrial revolutions,whereas their consumption increased at a slowing pace as the economy was growing continually;after the third industrial revolution,the consumption of fossil fuels decoupled gradually with the economic growth.As the industrial structure transformed as the industrial revolutions went on,more and more metals were used in the industries,and the consumption of different metals showed different trends.In recent years,a new technological revolution has surged mainly driven by the overall application of new information technologies.The technological advance in information,new energies,new materials,etc.,will speed up the industrial transformation and exert a deep effect on the demand of energy and metals.It can be inferred that the ratio of clean,non-polluting,renewable energy will rise while the ratio of fossil fuels will drop in the energy demand,and the demand of rare metals will perhaps enter a fast-growing period,while the demand of traditional bulk metals will fluctuate at mid-high levels.Following the new industrial revolution,China should adopt an energy transition strategy of developing low-carbon and free-carbon technologies simultaneously,reinforce the domestic and international metal supply system with the aim of enhancing global governance capability,strengthen the deep development of rich rare metals and broaden the overseas supply channels of scare rare metals. 展开更多
关键词 Technological improvement Industrial revolution ENERGY Metal resources EVOLUTION
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Microstructure and properties of Si_3N_4 ceramics obtained from addition of β-phase seeds and celsian
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作者 Jun yang Jiqiang Gao +2 位作者 jianfeng yang Guanjun Qiao Yonghong Luo 《Journal of University of Science and Technology Beijing》 CSCD 2006年第5期465-468,共4页
The silicon nitride based ceramics obtained by the addition of β-Si3N4 seeds was fabricated using celsian as the additive and by pressureless sintering. The microstructure of the material was observed and analyzed us... The silicon nitride based ceramics obtained by the addition of β-Si3N4 seeds was fabricated using celsian as the additive and by pressureless sintering. The microstructure of the material was observed and analyzed using XRD, SEM, and TEM and the mechanical response of this array microstructure was characterized for flexural strength and fracture behavior. The result shows that the growth of the larger aspect ratio grains initiate mainly from the seeds through the heterogeneous nucleation mechanism during the process of phase transformation, and the intergranular phase BaAl2Si20s services as good refractory materials. In contrast to conventional processing, a stable bimodal microstructure and complicated component with a lower cost can be achieved using the abovementioned process theoretically and practically. 展开更多
关键词 silicon nitride ceramics CELSIAN β-silicon nitride seed pressureless sintering microstructure properties
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A Novel Starting Impulse Suppression Method for Active Power Filter Based on Slowly Rising Curve
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作者 jianfeng yang Yu Ding 《Energy Engineering》 EI 2021年第6期1839-1853,共15页
With the widespread application of power electronic equipment in the power grid,the harmonic problem of the power grid becomes more pronounced,reducing the efficiency of power production,transmission,and utilization,a... With the widespread application of power electronic equipment in the power grid,the harmonic problem of the power grid becomes more pronounced,reducing the efficiency of power production,transmission,and utilization,and interfering with the normal operation of the power grid.Based on the requirements of harmonic suppression and power system protection,a shunt active power filter(SAPF)is proposed as an effective harmonic suppression method.However,there are problems with impulse current and impulse voltage in the starting process of SAPF.Impulse current and impulse voltage cause the power grid and switchgear to bear greater current stress and voltage stress,which seriously affect the security and reliability of the power grid and may damage the switchgear.To effectively solve the problem of impulse current and impulse voltage,the starting process of SAPF is divided into the uncontrolled rectification stage and the transition stage.The mathematical model of the DC side of APF is established.The causes of impulse current and impulse voltage in the uncontrolled rectifier and transition phases are analyzed.By introducing voltage square,a new starting impulse suppression strategy of active power filter based on the slow rising curve is proposed,fundamentally solving the problems of impulse current and impulse voltage.Simulation results verify the effectiveness and feasibility of this method. 展开更多
关键词 Shunt active power filter starting shock impulse current impulse voltage
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国有船企技能人才队伍管理机制的探索
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作者 杨剑锋 《广船科技》 2019年第4期49-53,共5页
在推进国有船企高质量发展进程中,技能人员队伍的建设至关重要。新时代对技能人员队伍建设带来新的机遇,但也同时面临一些新的问题。本文结合某国有船企在技能人员队伍建设方面的实践,思考如何创新技能人员队伍管理机制,培养造就一支&qu... 在推进国有船企高质量发展进程中,技能人员队伍的建设至关重要。新时代对技能人员队伍建设带来新的机遇,但也同时面临一些新的问题。本文结合某国有船企在技能人员队伍建设方面的实践,思考如何创新技能人员队伍管理机制,培养造就一支"有理想守信念、懂技术会创新、敢担当讲奉献"的造船技能人员队伍。 展开更多
关键词 人员队伍建设 技能人才队伍 技能人员 管理机制 创新技能 培养造就 实践 思考 新的问题
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太阳极轨天文台 被引量:4
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作者 邓元勇 周桂萍 +31 位作者 代树武 王颖 冯学尚 何建森 姜杰 田晖 杨尚斌 侯俊峰 颜毅华 甘为群 白先勇 李乐平 夏利东 黎辉 苏杨 熊明 张也弛 朱成林 林佳本 章海鹰 陈波 何玲平 封莉 张红鑫 孙明哲 张爱兵 陈林杰 谭宝林 张哲 杨建峰 杨孟飞 汪景琇 《科学通报》 EI CAS CSCD 北大核心 2023年第4期298-308,共11页
太阳极轨天文台利用高轨道倾角(≥80°)和小椭偏率轨道,将首次实现正面对太阳极区磁场和速度场高精度成像观测,结合多波段遥感和原位测量,为解决太阳磁活动周起源的世纪难题提供决定性观测,为破解“原始”高速太阳风的起源效应之谜... 太阳极轨天文台利用高轨道倾角(≥80°)和小椭偏率轨道,将首次实现正面对太阳极区磁场和速度场高精度成像观测,结合多波段遥感和原位测量,为解决太阳磁活动周起源的世纪难题提供决定性观测,为破解“原始”高速太阳风的起源效应之谜提供直接观测支撑,为理解日球层整体结构突破性创建数据驱动的日球数值模型. 展开更多
关键词 多波段遥感 数据驱动 原位测量 高精度成像 直接观测 整体结构 轨道倾角 数值模型
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黑暗三人格对职业成功的双重影响 被引量:1
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作者 杨建锋 刘苏瑾 +1 位作者 明晓东 曾莉 《中国人力资源开发》 北大核心 2023年第6期52-69,共18页
不难发现这样一类人:他们充分展现了黑暗三人格(自恋、马基雅维利主义、精神病态)的典型特征,狂妄自大、善于操纵、冷漠无情,却能够在职场上春风得意。关于黑暗三人格与职业成功这一主题,现有综述仅关注单个黑暗人格(马基雅维利主义)对... 不难发现这样一类人:他们充分展现了黑暗三人格(自恋、马基雅维利主义、精神病态)的典型特征,狂妄自大、善于操纵、冷漠无情,却能够在职场上春风得意。关于黑暗三人格与职业成功这一主题,现有综述仅关注单个黑暗人格(马基雅维利主义)对职业成功的影响,没有全面系统地梳理黑暗三人格对职业成功的影响机制。本文通过系统回顾和梳理相关研究,归纳出三个黑暗人格对主客观职业成功的双重影响(促进亦或阻碍)机制,并分析三者在影响职业成功的机制方面的异同。最后,建议未来研究关注黑暗三人格之外的负面人格,探究领导和下属之间黑暗人格的匹配程度及其对下属的影响,以及探究人工智能的应用与黑暗三人格个体在工作场景中的相互作用。 展开更多
关键词 自恋 马基雅维利主义 精神病态 主观职业成功 客观职业成功
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新特提斯洋俯冲与大气二氧化碳浓度变化的动力学联系 被引量:1
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作者 沈昊 赵亮 +6 位作者 郭正堂 袁怀玉 杨建锋 王欣欣 郭正府 邓成龙 吴福元 《Science Bulletin》 SCIE EI CAS CSCD 2023年第6期637-644,M0004,共9页
新特提斯洋的脱碳俯冲被认为在新生代气候变化中发挥了重要作用,但仍然缺少定量的研究.本研究使用改进的地震层析成像重建方法构建了过去的俯冲情景,并计算了印度-欧亚大陆碰撞区域的俯冲板块通量.新生代时期的俯冲板片通量和古气候参... 新特提斯洋的脱碳俯冲被认为在新生代气候变化中发挥了重要作用,但仍然缺少定量的研究.本研究使用改进的地震层析成像重建方法构建了过去的俯冲情景,并计算了印度-欧亚大陆碰撞区域的俯冲板块通量.新生代时期的俯冲板片通量和古气候参数的变化之间存在显著的同步性,表明这些过程之间存在因果关系.新生代早期,新特提洋内俯冲的关闭导致更多富含碳的沉积物沿着欧亚大陆边缘俯冲,为大陆弧火山的岩浆作用提供了更多的碳源,进一步引发了全球变暖.在全球气候达到早始新世峰值后,印度-欧亚大陆碰撞导致的新特提斯俯冲的突然终止造成了距今50~40 Ma期间大气中二氧化碳浓度的快速下降.距今40 Ma后,大气中的二氧化碳浓度逐渐降低,这可能是由于青藏高原的生长导致大陆风化作用增强所致.本文结果有助于更好地理解新特提斯洋演化的动态含义,并可能为未来的碳循环模型提供新的约束条件. 展开更多
关键词 Tectonic carbon cycling Neo-Tethyan subduction India-Eurasia collision Tectonic reconstruction Seismic tomography Climate change
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Disulfiram enhances the antitumor activity of cisplatin by inhibiting the Fanconi anemia repair pathway 被引量:1
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作者 Meng YUAN Qian WU +5 位作者 Mingyang ZHANG Minshan LAI Wenbo CHEN jianfeng yang Li JIANG Ji CAO 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2023年第3期207-220,共14页
A series of chemotherapeutic drugs that induce DNA damage,such as cisplatin(DDP),are standard clinical treatments for ovarian cancer,testicular cancer,and other diseases that lack effective targeted drug therapy.Drug ... A series of chemotherapeutic drugs that induce DNA damage,such as cisplatin(DDP),are standard clinical treatments for ovarian cancer,testicular cancer,and other diseases that lack effective targeted drug therapy.Drug resistance is one of the main factors limiting their application.Sensitizers can overcome the drug resistance of tumor cells,thereby enhancing the antitumor activity of chemotherapeutic drugs.In this study,we aimed to identify marketable drugs that could be potential chemotherapy sensitizers and explore the underlying mechanisms.We found that the alcohol withdrawal drug disulfiram(DSF)could significantly enhance the antitumor activity of DDP.JC-1 staining,propidium iodide(PI)staining,and western blotting confirmed that the combination of DSF and DDP could enhance the apoptosis of tumor cells.Subsequent RNA sequencing combined with Gene Set Enrichment Analysis(GSEA)pathway enrichment analysis and cell biology studies such as immunofluorescence suggested an underlying mechanism:DSF makes cells more vulnerable to DNA damage by inhibiting the Fanconi anemia(FA)repair pathway,exerting a sensitizing effect to DNA damaging agents including platinum chemotherapy drugs.Thus,our study illustrated the potential mechanism of action of DSF in enhancing the antitumor effect of DDP.This might provide an effective and safe solution for combating DDP resistance in clinical treatment. 展开更多
关键词 Disulfiram(DSF) Cisplatin(DDP) DNA damage Fanconi anemia(FA)repair Chemotherapy
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Dynamic modeling of tectonic carbon processes:State of the art and conceptual workflow 被引量:1
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作者 Liang ZHAO Zhengtang GUO +11 位作者 Huaiyu YUAN Xinxin WANG Hao SHEN jianfeng yang Baolu SUN Ning TAN Hui ZHANG Yonggang LIU yang LI Jiamin WANG Weiqiang JI Rixiang ZHU 《Science China Earth Sciences》 SCIE EI CAS CSCD 2023年第3期456-471,共16页
Plate tectonics plays a critical role in modulating atmospheric CO_(2)concentration on the geological timescale(≥106year).A growing consensus on tectonic and Earth’s CO_(2)history in the Cenozoic and deeper time pro... Plate tectonics plays a critical role in modulating atmospheric CO_(2)concentration on the geological timescale(≥106year).A growing consensus on tectonic and Earth’s CO_(2)history in the Cenozoic and deeper time provides solid restrictions and standards for testing tectonic carbon processes against global measurements.Despite this,modeling the causal relationship between tectonic events and atmospheric CO_(2)levels remains a challenge.We examine the current state of the global tectonic CO_(2)research and suggest a conceptual workflow for numerical experiments that integrates plate tectonics and deep carbon dynamics.Future tectonic carbon cycle modeling should include at least four modules:(1)simulation of carbon-carrying processes,such as carbon ingassing and outgassing at the scale of minerals;(2)calculation of CO_(2)fluxes in tectonic settings like subduction,mantle plume,and plate rifting;(3)reconstruction of carbon cycling within the plates-scale tectonic scenario,particularly involving the processes of supercontinent convergence and dispersion;and(4)comparison with atmospheric CO_(2)history data and iterations,aiming to find the coincidental link between different tectonic carbon fluxes and climate changes.According to our analysis,the recent advancements in each of the four modules have paved the path for a more general assembly.We envision that the large variety of carbon transportation parameters across more than ten orders of magnitude in both time and space is the primary technical hurdle in simulating tectonic carbon dynamics.We propose a boundary-condition-connected approach for simulating the global carbon cycle to realize carbon exchange between the solid earth and surface spheres. 展开更多
关键词 Tectonic carbon cycling Tectonic CO_(2)modeling Boundary-condition-connected approach
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基于三元自我角色视角的职业生涯建构理论述评 被引量:1
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作者 杨建锋 陈欢 +2 位作者 明晓东 孙彩云 朱建斌 《中国人力资源开发》 CSSCI 北大核心 2021年第5期25-44,共20页
在VUCA时代背景下,强调生涯适应的职业生涯建构理论对于指导个体的职业生涯显得尤为重要,更具时代价值。该理论使用三元自我角色——角色扮演者、主动追求者、自传写作者来理解个体的职业生涯建构,但最初对于该理论的实证研究和理论探... 在VUCA时代背景下,强调生涯适应的职业生涯建构理论对于指导个体的职业生涯显得尤为重要,更具时代价值。该理论使用三元自我角色——角色扮演者、主动追求者、自传写作者来理解个体的职业生涯建构,但最初对于该理论的实证研究和理论探讨都只侧重于对主动追求者的职业生涯适应过程这一模块进行探讨。本文通过对该理论相关研究的梳理,发现近年来研究者们加强了对三元自我角色在工作场所、职业生涯管理、生活设计干预等领域的应用和探讨,关于该理论的研究在研究内容、研究视角和研究方法上都得到了丰富。最后,本文从拓展依恋图式在职业生涯建构情境中的研究、加强职业角色扮演的跨文化研究、探索适应链的因果顺序、注重对特殊群体的职业生涯建构干预研究,以及该理论在组织管理领域和职业生涯教育领域中的应用六个方面对未来研究方向进行了展望。 展开更多
关键词 职业生涯建构理论 适应资源 生涯建构 依恋 生活设计
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