Objectives:This article aims to summarize a series of contingency management strategies of the Nursing Department in the centralized treatment of patients with coronavirus disease 2019(COVID-19).Methods:The strategies...Objectives:This article aims to summarize a series of contingency management strategies of the Nursing Department in the centralized treatment of patients with coronavirus disease 2019(COVID-19).Methods:The strategies of the Nursing Department included an early warning for prevention and control,taking functions of vertically commanding and horizontally coordinating,and reasonably allocating nursing workforce,to facilitate centralized treatment work in the in-hospital fever clinic,isolation wards and ICU,and referral and admission of critical patients.Five special groups were established in charge of training and examination,management and supervision,psychological support,logistical support,and reporting and publicity,respectively.Results:It was achieved that no deaths from critical patients and no medical staff,no other patients were infected.Conclusion:Through the implementation of these strategies,safe and efficient centralized treatment was ensured timely,orderly and sustainably.展开更多
[Objectives]This paper aimed to study the chemical composition of Rubus pirifolius Smith[Methods]A preliminary experiment was carried out using the qualitative reactions of various chemical constituents,in order to ro...[Objectives]This paper aimed to study the chemical composition of Rubus pirifolius Smith[Methods]A preliminary experiment was carried out using the qualitative reactions of various chemical constituents,in order to roughly detect the types of chemical constituents that may be contained in R.pirifolius Smith The ethanol extract of R.pirifolius Smith were separated and purified using silica gel column chromatography,silica gel thin-layer chromatography and recrystallization,and the chemicals obtained were identified using mass spectrometry,nuclear magnetic resonance and literature reference.[Results]The main constituents of R.pirifolius Smith are saponins,tannins,flavonoids,phytosterols,triterpenes and anthraquinones.A total of five compounds were isolated from the ethanol extract of R.pirifolius Smith,and they were identified asβ-sitosterol(1),arjunolic acid(2),stigmasterol-3-O-β-D-glucopyranoside(3),euscaphic acid(4)and 3,3′,4-trimethyle llegic acid(5).[Conclusions]Compounds 1,2,3,4 and 5 were isolated from R.pirifolius Smith for the first time.展开更多
As a globally popular leafy vegetable and a representative plant of the Asteraceae family,lettuce has great economic and academic significance.In the last decade,high-throughput sequencing,phenotyping,and other multi-...As a globally popular leafy vegetable and a representative plant of the Asteraceae family,lettuce has great economic and academic significance.In the last decade,high-throughput sequencing,phenotyping,and other multi-omics data in lettuce have accumulated on a large scale,thus increasing the demand for an integrative lettuce database.Here,we report the establishment of a comprehensive lettuce database,LettuceGDB(https://www.lettucegdb.com/).As an omics data hub,the current LettuceGDB includes two reference genomes with detailed annotations;re-sequencing data from over 1000 lettuce varieties;a collection of more than 1300 worldwide germplasms and millions of accompanying phenotypic records obtained with manual and cutting-edge phenomics technologies;re-analyses of 256 RNA sequencing datasets;a complete miRNAome;extensive metabolite information for representative varieties and wild relatives;epigenetic data on the genome-wide chromatin accessibility landscape;and various lettuce research papers published in the last decade.Five hierarchically accessible functions(Genome,Genotype,Germplasm,Phenotype,and O-Omics)have been developed with a user-friendly interface to enable convenient data access.Eight built-in tools(Assembly Converter,Search Gene,BLAST,JBrowse,Primer Design,Gene Annotation,Tissue Expression,Literature,and Data)are available for data downloading and browsing,functional gene exploration,and experimental practice.A community forum is also available for information sharing,and a summary of current research progress on different aspects of lettuce is included.We believe that LettuceGDB can be a comprehensive functional database amenable to data mining and database-driven exploration,useful for both scientific research and lettuce breeding.展开更多
Dear Editors,In recent years,human adenovirus (HAd V) infection has been prevalent in various regions in China (Duan et al.2021).Research in Guangzhou reported that 9.14%of fatal pneumonia cases showed HAd V-PCR posit...Dear Editors,In recent years,human adenovirus (HAd V) infection has been prevalent in various regions in China (Duan et al.2021).Research in Guangzhou reported that 9.14%of fatal pneumonia cases showed HAd V-PCR positive (Ou et al.2007).The severity and high mortality caused by HAd V have aroused the attention of pediatricians.展开更多
We theoretically studied the thermoelectric transport properties of a strongly correlated quantum dot system in the presence of the Kondo effect based on accurate numerical evaluations using the hierarchical equations...We theoretically studied the thermoelectric transport properties of a strongly correlated quantum dot system in the presence of the Kondo effect based on accurate numerical evaluations using the hierarchical equations of motion approach.The thermocurrent versus gate voltage shows a distinct sawtooth line-shape at high temperatures.In particular,the current changes from positive(hole charge)to negative(particle charge)in the electron number N=1 region due to the Coulomb blockade effect.However,at low temperatures,where the Kondo effect occurs,the thermocurrent’s charge polarity reverses,along with a significantly enhanced magnitude.As anticipated,the current sign can be analyzed by the occupation difference between particle and hole.Moreover,the characteristic turnover temperature can be further defined at which the influences of the Coulomb blockade and Kondo resonance are in an effective balance.Remarkably,the identified characteristic turnover temperature,as a function of the Coulomb interaction and dot-lead coupling,possessed a much higher value than the Kondo temperature.When a magnetic field is applied,a spin-polarized thermocurrent can be obtained,which could be tested in future experiments.展开更多
基金Zhejiang Medical Science and Technology Plan Project(2019RC167).
文摘Objectives:This article aims to summarize a series of contingency management strategies of the Nursing Department in the centralized treatment of patients with coronavirus disease 2019(COVID-19).Methods:The strategies of the Nursing Department included an early warning for prevention and control,taking functions of vertically commanding and horizontally coordinating,and reasonably allocating nursing workforce,to facilitate centralized treatment work in the in-hospital fever clinic,isolation wards and ICU,and referral and admission of critical patients.Five special groups were established in charge of training and examination,management and supervision,psychological support,logistical support,and reporting and publicity,respectively.Results:It was achieved that no deaths from critical patients and no medical staff,no other patients were infected.Conclusion:Through the implementation of these strategies,safe and efficient centralized treatment was ensured timely,orderly and sustainably.
基金Supported by Backbone Student Project of Professor Yang Shilin’s Team of Guangxi University of Chinese Medicine(YSL17016).
文摘[Objectives]This paper aimed to study the chemical composition of Rubus pirifolius Smith[Methods]A preliminary experiment was carried out using the qualitative reactions of various chemical constituents,in order to roughly detect the types of chemical constituents that may be contained in R.pirifolius Smith The ethanol extract of R.pirifolius Smith were separated and purified using silica gel column chromatography,silica gel thin-layer chromatography and recrystallization,and the chemicals obtained were identified using mass spectrometry,nuclear magnetic resonance and literature reference.[Results]The main constituents of R.pirifolius Smith are saponins,tannins,flavonoids,phytosterols,triterpenes and anthraquinones.A total of five compounds were isolated from the ethanol extract of R.pirifolius Smith,and they were identified asβ-sitosterol(1),arjunolic acid(2),stigmasterol-3-O-β-D-glucopyranoside(3),euscaphic acid(4)and 3,3′,4-trimethyle llegic acid(5).[Conclusions]Compounds 1,2,3,4 and 5 were isolated from R.pirifolius Smith for the first time.
基金supported by the Beijing Academy of Agriculture and Forestry Sciences(KJCX201907-2 to J.W.,KJCX201917 to C.Z.,and KJCX20200204 and KJCX20220105 to X.Y.)the Beijing Postdoctoral Research Foundation(2021-ZZ-133 to B.L.)the National Natural Science Foundation of China(31621001 to X.Y.).
文摘As a globally popular leafy vegetable and a representative plant of the Asteraceae family,lettuce has great economic and academic significance.In the last decade,high-throughput sequencing,phenotyping,and other multi-omics data in lettuce have accumulated on a large scale,thus increasing the demand for an integrative lettuce database.Here,we report the establishment of a comprehensive lettuce database,LettuceGDB(https://www.lettucegdb.com/).As an omics data hub,the current LettuceGDB includes two reference genomes with detailed annotations;re-sequencing data from over 1000 lettuce varieties;a collection of more than 1300 worldwide germplasms and millions of accompanying phenotypic records obtained with manual and cutting-edge phenomics technologies;re-analyses of 256 RNA sequencing datasets;a complete miRNAome;extensive metabolite information for representative varieties and wild relatives;epigenetic data on the genome-wide chromatin accessibility landscape;and various lettuce research papers published in the last decade.Five hierarchically accessible functions(Genome,Genotype,Germplasm,Phenotype,and O-Omics)have been developed with a user-friendly interface to enable convenient data access.Eight built-in tools(Assembly Converter,Search Gene,BLAST,JBrowse,Primer Design,Gene Annotation,Tissue Expression,Literature,and Data)are available for data downloading and browsing,functional gene exploration,and experimental practice.A community forum is also available for information sharing,and a summary of current research progress on different aspects of lettuce is included.We believe that LettuceGDB can be a comprehensive functional database amenable to data mining and database-driven exploration,useful for both scientific research and lettuce breeding.
基金supported by the Education Committee of Chongqing, China for Young Scholars (Chongqing Education Department [2019] No.13)Millions Talent Projects of Chongqing (Chongqing Commission [2018] NO.187)the Foundation of Children’s Hospital of Chongqing Medical University。
文摘Dear Editors,In recent years,human adenovirus (HAd V) infection has been prevalent in various regions in China (Duan et al.2021).Research in Guangzhou reported that 9.14%of fatal pneumonia cases showed HAd V-PCR positive (Ou et al.2007).The severity and high mortality caused by HAd V have aroused the attention of pediatricians.
基金the National Natural Science Foundation of China(Grant Nos.11804245,11747098,11504017,11774418,11674139,11834005,21633006,and U1930402)the China Postdoctoral Science Foundation(Grant No.2019M660431)the Program for the Innovative Talents of Taiyuan Institute of Technology。
文摘We theoretically studied the thermoelectric transport properties of a strongly correlated quantum dot system in the presence of the Kondo effect based on accurate numerical evaluations using the hierarchical equations of motion approach.The thermocurrent versus gate voltage shows a distinct sawtooth line-shape at high temperatures.In particular,the current changes from positive(hole charge)to negative(particle charge)in the electron number N=1 region due to the Coulomb blockade effect.However,at low temperatures,where the Kondo effect occurs,the thermocurrent’s charge polarity reverses,along with a significantly enhanced magnitude.As anticipated,the current sign can be analyzed by the occupation difference between particle and hole.Moreover,the characteristic turnover temperature can be further defined at which the influences of the Coulomb blockade and Kondo resonance are in an effective balance.Remarkably,the identified characteristic turnover temperature,as a function of the Coulomb interaction and dot-lead coupling,possessed a much higher value than the Kondo temperature.When a magnetic field is applied,a spin-polarized thermocurrent can be obtained,which could be tested in future experiments.