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社区获得性肺炎合并糖尿病患者的临床特征和死亡危险因素分析
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作者 马建芳 黄晓玲 +2 位作者 李艳华 马狄 袁开芬 《昆明医科大学学报》 CAS 2024年第2期123-130,共8页
目的 探讨社区获得性肺炎(community-acquired pneumonia,CAP)合并糖尿病(diabetes mellitus,DM)患者的临床特征和住院期间死亡的危险因素。方法 回顾性收集昆明医科大学第二附属医院2018年1月至2022年1月住院治疗的566例CAP患者资料,... 目的 探讨社区获得性肺炎(community-acquired pneumonia,CAP)合并糖尿病(diabetes mellitus,DM)患者的临床特征和住院期间死亡的危险因素。方法 回顾性收集昆明医科大学第二附属医院2018年1月至2022年1月住院治疗的566例CAP患者资料,根据患者是否合并糖尿病分为单纯CAP组(n=478),CAP合并糖尿病(CAP+DM)组(n=88),再根据患者住院期间是否死亡将CAP+DM组(n=88)分为存活组(n=69)和死亡组(n=19)。分别比较不同分组患者的临床资料和入院时的实验室化验指标,采用Cox回归分析筛选CAP+DM组患者住院期间死亡的危险因素,绘制受试者工作特征(receiver operating characteristic,ROC)曲线评估危险因素对住院期间死亡的预测价值。结果 与单纯CAP组比较,CAP+DM组患者在年龄、合并高血压、冠心病、CURB-65评分、中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)、C反应蛋白(C-reactive protein,CRP)、降钙素原(procalcitonin,PCT)、白蛋白(albumin,ALB)、前白蛋白(prealbumin,PA)、葡萄糖(glucose,GLU)、血清钾(potassium,K)、钙(calcium,Ca)、磷(phosphorus,P)、镁(magnesium,Mg)、乳酸(lactic acid,Lac),无创通气时间、入住ICU率及病死率比较上,差异有统计学意义(P <0.05);与存活组比较,死亡组患者在CURB-65评分、NLR、CRP、PCT、GIU、ALB、PA、血清铁(iron,Fe)、Ca、无创通气时间、入住ICU率比较上,差异有统计学意义(P <0.05)。Cox回归分析显示,NLR水平升高、PA水平下降是CAP合并糖尿病患者住院期间死亡的危险因素(P <0.05)。PA截断值为91 mg/L时,预测合并糖尿病的CAP患者住院期间死亡的曲线下面积(area under curve,AUC)、灵敏度和特异度分别为0.849,84.2%、81.2%。结论 CAP合并糖尿病的患者较单纯的CAP患者病情更严重,预后更差,PA对这类患者的预后具有良好的预测价值,应早期检测并积极干预,以降低患者的住院病死率。 展开更多
关键词 社区获得性肺炎 糖尿病 临床特征 病死率 前白蛋白
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Spatiotemporal expression and application of urban residential solar rights based on CityGML-LADM
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作者 Chengcheng Liu Haihong Zhu +2 位作者 Lin Li jianfang ma Feng Li 《International Journal of Digital Earth》 SCIE EI 2023年第1期2301-2321,共21页
Property disputes are frequent occurrences in rapidly urbanizing regions.Among the legal issues concerning building property rights,solar rights disputes are prevalent because text clauses on solar rights rely on dive... Property disputes are frequent occurrences in rapidly urbanizing regions.Among the legal issues concerning building property rights,solar rights disputes are prevalent because text clauses on solar rights rely on diverse measurements or calculations.Moreover,previous studies on measuring solar rights addressed only the sunlight duration and neglected the daylight factor(daylighting coefficient),which is an integral component of solar rights.Therefore,this study proposes a 3D spatiotemporal model for effectively measuring solar rights by taking both the sunlight duration and the daylight factor into consideration.This model would be technologically valuable in avoiding or settling legal disputes.Taking the specifications of the solar rights of building property in China as a case study,the proposed spatiotemporal model clarifies the complete solar rights of residential units and is implemented by integrating a geometric model from CityGML with a property model,namely,the Land Administration Domain Model(LADM).Three real typical cases are adopted to show the applicability and benefit of the 3D spatiotemporal model in resolving legal property disputes. 展开更多
关键词 Solar rights Spatiotemporal expression CITYGML LADM Legal disputes
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Parkinson’s disease in China:a forty-year growing track of bedside work 被引量:62
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作者 Gen Li jianfang ma +4 位作者 Shishuang Cui Yixi He Qin Xiao Jun Liu Shengdi Chen 《Translational Neurodegeneration》 SCIE CAS 2019年第1期270-278,共9页
The number and health burden of Parkinson’s disease increase rapidly in China.It is estimated that China will have nearly half of the Parkinson’s disease population in the world in 2030.In this review,we present an ... The number and health burden of Parkinson’s disease increase rapidly in China.It is estimated that China will have nearly half of the Parkinson’s disease population in the world in 2030.In this review,we present an overview of epidemiology and health economics status of Parkinson’s disease across China and discuss the risk factors of Parkinson’s disease and related complications.From the view of clinical research,we also discuss the current status of clinical trials,diagnostic biomarkers,treatment of Parkinson’s disease,tertiary network and post-occupation education in Chinese Parkinson’s disease clinics. 展开更多
关键词 Parkinson’s disease Tertiary network Clinical research Diagnosis
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A series of coordination polymers constructed from flexible bis(benzimidazole)ether ligands and different carboxylates 被引量:1
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作者 Hua Wu LaiPing Zhang +2 位作者 HaiYan Liu Jin Yang jianfang ma 《Science China Chemistry》 SCIE EI CAS 2009年第9期1490-1497,共8页
Six new coordination polymers constructed from two structurally related ligands, 2,2′-bis(2-methylbenzimidazole)ether (L1) and 2,2′-bis(2-ethylbenzimidazole)ether (L2), have been synthesized. They are [Cu(L1)(bz)2] ... Six new coordination polymers constructed from two structurally related ligands, 2,2′-bis(2-methylbenzimidazole)ether (L1) and 2,2′-bis(2-ethylbenzimidazole)ether (L2), have been synthesized. They are [Cu(L1)(bz)2] (1), [Cu(L2)(bz)2] (2), [Zn2(L1)(m-bdc)2] (3), [Cd2(L2)(m-bdc)2(H2O)]2·H2O (4), [Zn(L1)(OH-bdc)-(H2O)] (5) and [Zn2(L2)(btca)] (6), where Hbz = benzoic acid, m-H2bdc = 1,3-benzenedicarboxylic acid, OH-H2bdc = 5-hydroxyisophthalic acid, and H4btca = 1,2,4,5-benzenetetracarboxylic acid. In 1 and 2, the bidentate N-donor ligands (L1 and L2) bridge neighboring metal centers to form 1D single chains. The bz anions are attached on both sides of the chains. In 3 and 4, the N-donor ligands (L1 and L2) in cis conformations bridge two metal centers to generate a [M2(L1)]4+ unit (M = Zn(Ⅱ) and Cd(Ⅱ)). The adjacent [M2(L1)]4+ units are further linked via the dicarboxylate anions to form 1D double chain structures. In 5, the Zn(Ⅱ) cations are bridged by OH-m-bdc anions to form an infinite polymeric chain. The L1 ligands are attached on one side of the chain in a monodentate mode. In 6, two Zn(Ⅱ) cations are bridged by two L2 ligands to form a [ZnL2]24+ ring, which is further linked by btca anions to generate a 2D layer. The luminescent properties of the ligands and 3―6 in the solid state at room temperature were also studied. 展开更多
关键词 coordination polymers FLEXIBLE LIGAND CARBOXYLATE LIGAND photoluminescence
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