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Disruption of KDM4C-ALDH1 A3 feed-forward loop inhibits sternness,tumorigenesis and chemoresistance of gastric cancer stem cells
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作者 Tingyuan Lang Jia Xu +7 位作者 Lei Zhou Zhiqi Zhang Xinli Ma Jiayi Gu Jingshu Liu Yunzhe Li Dongyan Ding jiangfeng qiu 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第10期2975-2977,共3页
Dear Editor,Gastric cancer(GC)is a considerable global health burden;the median survival of advaneed GC is less than 1 year.^(1)Cancer stem cells(CSCs),a small population of cancer cells with stem cell-like properties... Dear Editor,Gastric cancer(GC)is a considerable global health burden;the median survival of advaneed GC is less than 1 year.^(1)Cancer stem cells(CSCs),a small population of cancer cells with stem cell-like properties,are the major cause of treatme nt failure,in eluding GC,2 however,the mechanisms underlying stemness maintenanee of GC stem cells(GCSCs)are still poorly understood. 展开更多
关键词 CANCER Gastric CANCER
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