Surface-grafted poly(ethylene glycol) (PEG) molecules are known to prevent protein adsorption to the surface. Nitinol samples were coated under tetraglyme ECR cold plasma conditions to enhance its biocompatibility. Th...Surface-grafted poly(ethylene glycol) (PEG) molecules are known to prevent protein adsorption to the surface. Nitinol samples were coated under tetraglyme ECR cold plasma conditions to enhance its biocompatibility. The modified Nitinol surfaces were characterized by high resolution ESCA and contact angle, it was demonstrated that the deposited PEG-like coatings were built up mainly of-CH2-CH2-O- linkages in surfaces. The surface wettability of the modified Nitinol was increased compared with the control surface. Human plasma protein was adsorbed on Nitinol evaluated by SEM, the protein adsorption on modified surfaces decreased rapidly. Thus, the potential benefits of cold plasma technique will be of use to the biomedical industries improving the biocompatibility of metals.展开更多
The macromolecular structures on nitinol surfaces were prepared by ECR microwave cold-plasma of tetraglyme conditions. The surface chemistry was characterized by high resolution ESCA. The results showed that th...The macromolecular structures on nitinol surfaces were prepared by ECR microwave cold-plasma of tetraglyme conditions. The surface chemistry was characterized by high resolution ESCA. The results showed that the modified nitinol surfaces were built up mainly of -CH2-CH2-O- linkages and were particularly effective in preventing platelet adhesion.展开更多
基金The project was supported by the National Natural Science Foundation of China(NSFC)(Grant No.19972071,50274065)subsidized by the Special Funds for Major State Basic Research Project(“973”Project)(Grant No.2002CB412704).
文摘Surface-grafted poly(ethylene glycol) (PEG) molecules are known to prevent protein adsorption to the surface. Nitinol samples were coated under tetraglyme ECR cold plasma conditions to enhance its biocompatibility. The modified Nitinol surfaces were characterized by high resolution ESCA and contact angle, it was demonstrated that the deposited PEG-like coatings were built up mainly of-CH2-CH2-O- linkages in surfaces. The surface wettability of the modified Nitinol was increased compared with the control surface. Human plasma protein was adsorbed on Nitinol evaluated by SEM, the protein adsorption on modified surfaces decreased rapidly. Thus, the potential benefits of cold plasma technique will be of use to the biomedical industries improving the biocompatibility of metals.
基金supported by the National Natural Science Foundation of China(NNSFC)(Grant No.19972071,50274065)subsidized by the Special Funds for Major State Basic Research Project("973"Project)(Grant No.2002CB412704)
文摘The macromolecular structures on nitinol surfaces were prepared by ECR microwave cold-plasma of tetraglyme conditions. The surface chemistry was characterized by high resolution ESCA. The results showed that the modified nitinol surfaces were built up mainly of -CH2-CH2-O- linkages and were particularly effective in preventing platelet adhesion.
