A novel glucose biosensor based on graphene nanosheets(GNs)modified gold nanowire arrays(AuNWAs)electrode was constructed.Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminu...A novel glucose biosensor based on graphene nanosheets(GNs)modified gold nanowire arrays(AuNWAs)electrode was constructed.Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates.GNs were synthesized through a public route involving graphite oxidation,exfoliation,and chemical reduction.Field emission scanning electron microscope and high-resolution transmission electron microscope were employed to characterize the asprepared AuNWAs and GNs.Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method.The cyclic voltammetry results showed that the GNs-AuNWAs-based glucose biosensors have high catalysis activity to hydrogen peroxide(H2O2)than those modified with GNs or AuNWAs only.Furthermore,amperometric response was employed to detect glucose concentration owing to its simplicity,high selectivity,and relative low cost.Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sensitivity of 40.25 lA cm-2(mmol/L)-1,low detection limit of 0.02 mmol/L,and a linear range from 0.02 to 3 mmol/L.展开更多
基金supported by the National Natural Science Foundation of China (91023030,51072044,51102071,51172059,and 51272063)the International Scientific and Technological Cooperation Project of Anhui Province (10080703017)
文摘A novel glucose biosensor based on graphene nanosheets(GNs)modified gold nanowire arrays(AuNWAs)electrode was constructed.Highly ordered gold nanowire arrays were prepared by direct electrodeposition in anodic aluminum oxide templates.GNs were synthesized through a public route involving graphite oxidation,exfoliation,and chemical reduction.Field emission scanning electron microscope and high-resolution transmission electron microscope were employed to characterize the asprepared AuNWAs and GNs.Glucose oxidase was immobilized on the surface of GNs-AuNWAs modified electrode via a cross-linking method.The cyclic voltammetry results showed that the GNs-AuNWAs-based glucose biosensors have high catalysis activity to hydrogen peroxide(H2O2)than those modified with GNs or AuNWAs only.Furthermore,amperometric response was employed to detect glucose concentration owing to its simplicity,high selectivity,and relative low cost.Glucose biosensors based on GNs-AuNWAs showed excellent performance with high sensitivity of 40.25 lA cm-2(mmol/L)-1,low detection limit of 0.02 mmol/L,and a linear range from 0.02 to 3 mmol/L.
