Review on the Anchoring Mechanism and Application Research of Compression-Type Anchor

To apply the compression-type anchor to deep roadways, this paper analyzes and summaries the bearing mechanism, shear stress distribution of the grout body and engineering application of the compression-type anchor. The analysis shows that the compression-type anchor has the advantages of reasonable grout body stress form, high loading capacity, good corrosion resistance and durability. The analysis also indicates that further study on the stress distribution of the compression-type anchor’s grout body and the design of a new compression-type anchor with high strength initial support, simple structure, and small diameter that is suitable for the surrounding rock in deep roadway engineering is necessary to apply compression-type anchor supporting technology to the deep roadway.

Numerical Simulation of the Relationship between the Width of Destressed Zone and Blasthole Depth

Overstress in the surrounding rock of the roadway is a key reason that causes failures of deep roadways. Destressing blasting is one of the promising techniques that could improve the supporting quality. If the depth of the pressure relief blast hole is too shallow, the surrounding rock of the roadway will be broken or even collapsed. If the pressure relief blast hole is too deep, the pressure relief area will be located in the deep part of the surrounding rock of the roadway, which cannot achieve the purpose of releasing the stress in the shallow part of the surrounding rock and cause waste of the blast hole. The width or range of the pressure relief area should just fall in the high stress area of the surrounding rock of the roadway, so the pressure relief blast hole should have a reasonable depth. In order to quantitatively describe the relationship between borehole depth and the width of the stress relief zone, numerical simulations were carried out in ANSYS according to different borehole depths. The results show that the optimal destressing effect is achieved when borehole depth is 4 m. Peak stress of and is significantly reduced by 30.51% and 49.07% after blasting. Meanwhile, the high-stress area shifts about 4.8 m from the roadside to the depth of surrounding rock, thus a 3.8 m wide stress relief zone is formed around the roadside, thus, the aim of quantizing the effects of destress blasting is achieved.

The Identification of Three Sizes of Core Proteins during the Establishment of Persistent Hepatitis C Virus Infection in vitro

Similar to Hepatitis C virus (HCV) infection in humans, HCVcc infection can also result in persistent and chronic infection. The core protein is a variable protein and exists in several sizes. Some sizes of core proteins have been reported to be related to chronic HCV infection. To study the possible role of the core protein in persistent HCV infection, a persistent HCVcc infection was established, and the expression of the core protein was analysed over the course of the infection. The results show that there are three sizes of core proteins (p24, p21 and p19) expressed during the establishment of persistent HCVcc infection. Of these, the p21 core protein is the mature form of the HCV core protein. The p24 core protein is the phosphorylated form of p21. The p19 core protein appears to be a functional by-product generated during the course of infection. These three core proteins are all localized in the cytoplasm and can be encapsidated into the HCV virion. The appearance of the p19 and p24 core proteins might be related to acute HCVcc infection and chronic infection respectively and may play an important role in the pathology of a HCV infection.