In this article, a new variable leakage flux reverse salient-pole motor(VLF-RSPM) is raised to widen the speed range. The innovation is to realize both reverse salient-pole characteristics and variable leakage flux ch...In this article, a new variable leakage flux reverse salient-pole motor(VLF-RSPM) is raised to widen the speed range. The innovation is to realize both reverse salient-pole characteristics and variable leakage flux characteristics by using a method of adding magnetic bridges and magnetic barriers. Firstly, the evolution of the topological structure and working principle of the motor are introduced. Secondly, based on 2D Finite Element Analysis(FEA), the electromagnetic properties and noise of the motor are analyzed in detail, and the electromagnetic properties are contrasted with that of the conventional V-type synchronous motor(CVTSM). The results show that VLF-RSPM has the advantages of small torque ripple, strong magnetic weakening ability, low noise, high efficiency, and low risk of permanent magnet demagnetization under different conditions. In addition, it is verified that the proposed motor extends the speed range.展开更多
Objective： This study aims to investigate the feasibility, safety and efficacy of triplet regimen of neoadjuvant chemotherapy in patients with locally advanced resectable colon cancer.Methods： Patients with clinical...Objective： This study aims to investigate the feasibility, safety and efficacy of triplet regimen of neoadjuvant chemotherapy in patients with locally advanced resectable colon cancer.Methods： Patients with clinical stage IIIb colon cancer received a perioperative triple chemotherapy regimen（oxaliplatin 85 mg/m2 and irinotecan 150 mg/m2, combined with folinic acid 200 mg, 5-fluorouracil 500 mg bolus and then 2,400 mg/m2 by 44 h infusion or capecitabine 1 g/m2 or S-1 40–60 mg b.i.d orally d 1–10, repeated at 2-week intervals） for 4 cycles. Complete mesocolic excision was scheduled 2–6 weeks after completion of neoadjuvant treatment and followed by a further 6 cycles of FOLFOXIRI or XELOX. Primary outcome measures of this stage II trial were feasibility, safety, tolerance and efficacy of neoadjuvant treatment.Results： All 23 patients received neoadjuvant chemotherapy and underwent surgery. Twenty-one patients（91.3%） had reductions in tumor volume after neoadjuvant treatment, and 13 patients（56.5%） had grade 3–4toxicity. No patients had severe complications from surgery. Preoperative therapy resulted in significant downstaging of T-stage and N-stage compared with the baseline clinical stage including one pathological complete response.Conclusions： Neoadjuvant triple chemotherapy has high activity and acceptable toxicity and perioperative morbidity, and is feasible, tolerable and effective for locally advanced resectable colon cancer.展开更多
In this paper,a controllable leakage flux reverse salient permanent magnet synchronous motor(CLF-RSPMSM)is designed,which has the advantages of wide speed range and low irreversible demagnetization risk.Firstly,the pr...In this paper,a controllable leakage flux reverse salient permanent magnet synchronous motor(CLF-RSPMSM)is designed,which has the advantages of wide speed range and low irreversible demagnetization risk.Firstly,the principle of controllable leakage flux and reverse saliency effect is introduced,and the design of the rotor flux barrier is emphatically discussed.Secondly,multiple design variables are stratified by the comprehensive sensitivity method,and the main variables are screened out.Then the relationship between the main variables and the optimization goal is discussed according to the response surface diagram.Thirdly,a sequential nonlinear programming algorithm(SNP)is used to optimize the three optimization objectives comprehensively.Finally,the electromagnetic performance of the proposed motor is compared with the initial IPM motor,the mechanical strength of the proposed rotor is analyzed,and the results verify the effectiveness of the design and optimization method of the proposed motor.展开更多
A novel mechanical variable-leakage-flux interior permanent magnet machine(MVLF-IPMM)is proposed for electric vehicles(EVs)in this paper,which employs a mechanical flux-regulating device and auxiliary rotatable magnet...A novel mechanical variable-leakage-flux interior permanent magnet machine(MVLF-IPMM)is proposed for electric vehicles(EVs)in this paper,which employs a mechanical flux-regulating device and auxiliary rotatable magnetic poles.The magnetic poles acting as the flux adjustors can be rotated by the additional device to vary the leakage flux in magnetic circuit and realize the adjustment of the PM flux linkage.Due to the flux-regulating effect,the flux distribution in this machine is complex and changeable.Therefore,the working principle is illustrated in detail.To obtain the perfect coordination between the dominant magnetic poles and auxiliary magnetic poles,a multi-objective optimization method is presented based on the parameter sensitivity analysis combining with the Coefficient of Prognosis(CoP).Then,some design parameters with strong sensitive are selected by the sensitivity analysis and the initial model of the proposed motor is optimized by utilizing the multi-objective genetic algorithm(MOGA).According to the result of the optimization,the machine performances of the initial and the optimal design under the different flux states are compared and analyzed to verify the validity of the new variable-flux motor and the optimization method.展开更多
In this paper,a novel intensifying-flux variable flux-leakage interior permanent magnet(IFVF-IPM)machine is proposed,in which flux barriers were designed deliberately between the adjacent poles to obtain intensifying-...In this paper,a novel intensifying-flux variable flux-leakage interior permanent magnet(IFVF-IPM)machine is proposed,in which flux barriers were designed deliberately between the adjacent poles to obtain intensifying-flux effect and variable flux-leakage property.The rotor topology and design principles of the proposed machine are also introduced.Then,a multi-objective optimization method is adopted based on the sensitivity analysis,and some design variables of IFVF-IPM machine with strong sensitivity are selected to optimization progress by using the non-dominated sorting genetic algorithm-Ⅱ(NSGA-Ⅱ).Moreover,the electromagnetic characteristics of conventional IPM machine,conventional IFVF-IPM machine(CIFVF-IPM)and the novel IFVF-IPM machine are compared based on the finite element analysis(FEA)method which includes flux linkage,inductances characteristic,torque-speed envelops and power characteristic,as well as evaluation of the risk of irreversible demagnetization.Finally,the experiment results show that the IFVF-IPM machine has a better performance in flux weakening capability for wide speed range and a lower risk of irreversible demagnetization,which indicates the validity and feasibility of the proposed machine.展开更多
基金supported by National Natural Science Foundation of China Grant No. 52067008China Jiangxi Provincial Planning Project Grant No. 20181BAB206035Qingjiang Excellent Young Talents Program,Jiangxi University of Science and Technology (JXUST)。
文摘In this article, a new variable leakage flux reverse salient-pole motor(VLF-RSPM) is raised to widen the speed range. The innovation is to realize both reverse salient-pole characteristics and variable leakage flux characteristics by using a method of adding magnetic bridges and magnetic barriers. Firstly, the evolution of the topological structure and working principle of the motor are introduced. Secondly, based on 2D Finite Element Analysis(FEA), the electromagnetic properties and noise of the motor are analyzed in detail, and the electromagnetic properties are contrasted with that of the conventional V-type synchronous motor(CVTSM). The results show that VLF-RSPM has the advantages of small torque ripple, strong magnetic weakening ability, low noise, high efficiency, and low risk of permanent magnet demagnetization under different conditions. In addition, it is verified that the proposed motor extends the speed range.
文摘Objective： This study aims to investigate the feasibility, safety and efficacy of triplet regimen of neoadjuvant chemotherapy in patients with locally advanced resectable colon cancer.Methods： Patients with clinical stage IIIb colon cancer received a perioperative triple chemotherapy regimen（oxaliplatin 85 mg/m2 and irinotecan 150 mg/m2, combined with folinic acid 200 mg, 5-fluorouracil 500 mg bolus and then 2,400 mg/m2 by 44 h infusion or capecitabine 1 g/m2 or S-1 40–60 mg b.i.d orally d 1–10, repeated at 2-week intervals） for 4 cycles. Complete mesocolic excision was scheduled 2–6 weeks after completion of neoadjuvant treatment and followed by a further 6 cycles of FOLFOXIRI or XELOX. Primary outcome measures of this stage II trial were feasibility, safety, tolerance and efficacy of neoadjuvant treatment.Results： All 23 patients received neoadjuvant chemotherapy and underwent surgery. Twenty-one patients（91.3%） had reductions in tumor volume after neoadjuvant treatment, and 13 patients（56.5%） had grade 3–4toxicity. No patients had severe complications from surgery. Preoperative therapy resulted in significant downstaging of T-stage and N-stage compared with the baseline clinical stage including one pathological complete response.Conclusions： Neoadjuvant triple chemotherapy has high activity and acceptable toxicity and perioperative morbidity, and is feasible, tolerable and effective for locally advanced resectable colon cancer.
基金This work was supported by the National Natural Science Foundation of China under Grant no.52067008in part by the Plan Project of Jiangxi Province of P.R.China under grant no.GJJ160598 and 20181BAB206035,and in part by the Program of Qingjiang Excellent Young Talents.
文摘In this paper,a controllable leakage flux reverse salient permanent magnet synchronous motor(CLF-RSPMSM)is designed,which has the advantages of wide speed range and low irreversible demagnetization risk.Firstly,the principle of controllable leakage flux and reverse saliency effect is introduced,and the design of the rotor flux barrier is emphatically discussed.Secondly,multiple design variables are stratified by the comprehensive sensitivity method,and the main variables are screened out.Then the relationship between the main variables and the optimization goal is discussed according to the response surface diagram.Thirdly,a sequential nonlinear programming algorithm(SNP)is used to optimize the three optimization objectives comprehensively.Finally,the electromagnetic performance of the proposed motor is compared with the initial IPM motor,the mechanical strength of the proposed rotor is analyzed,and the results verify the effectiveness of the design and optimization method of the proposed motor.
基金the National Natural Science Foundation of China under grant no.51767009in part by the Plan Project of Jiangxi Province of P.R.China under grant no.GJJ160598 and 20181BAB206035in part by the Program of Qingjiang Excellent Young Talents,Jiangxi University of Science and Technology(JXUST)。
文摘A novel mechanical variable-leakage-flux interior permanent magnet machine(MVLF-IPMM)is proposed for electric vehicles(EVs)in this paper,which employs a mechanical flux-regulating device and auxiliary rotatable magnetic poles.The magnetic poles acting as the flux adjustors can be rotated by the additional device to vary the leakage flux in magnetic circuit and realize the adjustment of the PM flux linkage.Due to the flux-regulating effect,the flux distribution in this machine is complex and changeable.Therefore,the working principle is illustrated in detail.To obtain the perfect coordination between the dominant magnetic poles and auxiliary magnetic poles,a multi-objective optimization method is presented based on the parameter sensitivity analysis combining with the Coefficient of Prognosis(CoP).Then,some design parameters with strong sensitive are selected by the sensitivity analysis and the initial model of the proposed motor is optimized by utilizing the multi-objective genetic algorithm(MOGA).According to the result of the optimization,the machine performances of the initial and the optimal design under the different flux states are compared and analyzed to verify the validity of the new variable-flux motor and the optimization method.
基金This work was supported in part by the National Natural Science Foundation of China under grant no.52067008.
文摘In this paper,a novel intensifying-flux variable flux-leakage interior permanent magnet(IFVF-IPM)machine is proposed,in which flux barriers were designed deliberately between the adjacent poles to obtain intensifying-flux effect and variable flux-leakage property.The rotor topology and design principles of the proposed machine are also introduced.Then,a multi-objective optimization method is adopted based on the sensitivity analysis,and some design variables of IFVF-IPM machine with strong sensitivity are selected to optimization progress by using the non-dominated sorting genetic algorithm-Ⅱ(NSGA-Ⅱ).Moreover,the electromagnetic characteristics of conventional IPM machine,conventional IFVF-IPM machine(CIFVF-IPM)and the novel IFVF-IPM machine are compared based on the finite element analysis(FEA)method which includes flux linkage,inductances characteristic,torque-speed envelops and power characteristic,as well as evaluation of the risk of irreversible demagnetization.Finally,the experiment results show that the IFVF-IPM machine has a better performance in flux weakening capability for wide speed range and a lower risk of irreversible demagnetization,which indicates the validity and feasibility of the proposed machine.
基金This work was supported by the National Natural Science Foundation of China(Grant No.51805307)the Natural Science Basic Research Program of Shaanxi(Grant Nos.2021JQ-574 and 2023-JC-YB-068).
