Study on the Tangential Tensile Mechanical Properties of Moso Bamboo

In this work,we used tensile tests to analyze the tangential failure forms of raw bamboo and determine a relationship between tangential tensile strength,elastic modulus,position,density,and moisture content.We found that the tangential mechanical properties of the culm wall were mainly dependent on the mechanical properties of the basic structure of the thin wall.Formulas for calculating the tangential tensile strength of moso bamboo and adjusting the moisture content were also determined.The tangential tensile strength and the tangential tensile modulus of elasticity(TTMOE)followed:outer>middle>inner,and diaphragm>bamboo node>culm wall.Below the fiber saturation point,the tangential tensile strength and TTMOE values of the bamboo gradually decreased with increasing moisture content.When the moisture content was 15%,the tangential tensile strengths of the inner,middle,outer,culm wall,bamboo node,and diaphragm samples of the five-year-old moso bamboo were 3.17,3.29,3.31,3.24,3.67,and 8.85 MPa,respectively.Furthermore,their TTMOE values were 215.09,227.98,238.45,224.04,267.21,and 559.27 MPa,respectively.Hence,this study provides a theoretical basis for future research on bamboo cracking.

Hydrophobic Poplar Prepared via High Voltage Electric Field(HVEF)with Copper as Electrode Plate

In order to improve hydrophobic characteristics which will affect the service performance of fast-growing poplar due to growing bacteria in the humid environment.In this study,a simple method was proposed to treat poplar via the high voltage electric field(HVEF)with copper as the electrode plate.Scanning electron microscope(SEM),Fourier transforms infrared spectroscopy(FTIR),X-ray diffraction(XRD)and contact angle tester were adopted to evaluate the surface morphology,surface group of poplar,crystallinity and wettability under HVEF.It was found by SEM that a large number of copper particles were uniformly attached to the surface of poplar.In all three sections,the weight percentage of the Cu element was accounting for more than half.The diffraction peaks of copper-containing compounds appeared in the(XRD).FTIR analysis confirmed that the reaction between copper and poplar took place.The surface contact angle of three sections of poplar increased in the following order:cross section<radial section<tangential section(increased by 34°,45°and 53°,respectively).An environmentfriendly and efficient method of HVEF treating fast-growing wood with copper as the electrode plate can promote its outdoor application.

Structure Design and Properties of Three-Layer Particleboard Based on High Voltage Electrostatic Field(HVEF)

In this study,the effects of three different particle sizes of wood wastes(A=–8+12 mesh;B=–12+20 mesh;C=–20+30 mesh)and factory shavings(D)on the properties of particleboard were investigated.According to the test results,three-layer particleboard was designed.Particleboard face layers made with mixture of A,B,and C.The core layer made with D.The ratio of core layer to face layers is 50:50.Three-layer particleboard were fabricated with 12%urea-formaldehyde(UF)resins and three different high voltage electrostatic field intensities(0 kv,30 kv,60 kv).The internal bond(IB)strength,modulus of rupture(MOR),modulus of elasticity(MOE),thickness swelling(TS),and water absorption(WA)of particleboard were evaluated.The density distribution of the three-layer particleboard were examined by vertical density profiles(VDP),and the bonding mechanism and functional groups changes in the particles were analyzed by FTIR analysis.The results showed that HVEF treatment intensity play a remarkable role in properties of particleboard.The particleboard with higher electrostatic field intensities treatment has higher MOE,MOR,IB,and TS.Under HVEF treatment(60 kv),the MOR,modulus of MOE,and IB of three-layer particleboard were 23.61 N/mm^(2),2787.09 N/mm^(2),and 0.86 N/mm^(2),respectively.FTIR indicated that the surface activity of wood particles was increased electric field treatment.

Proteomics provides individualized options of precision medicine for patients with gastric cancer

While precision medicine driven by genome sequencing has revolutionized cancer care,such as lung cancer,its impact on gastric cancer(GC)has been minimal.GC patients are routinely treated with chemotherapy,but only a fraction of them receive the clinical benefit.There is an urgent need to develop biomarkers or algorithms to select chemo-sensitive patients or apply targeted therapy.Here,we carried out retrospective analyses of 1,020 formalin-fixed,paraffin-embedded GC surgical resection samples from 5 hospitals and developed a mass spectrometry-based workflow for proteomic subtyping of GC.We identified two proteomic subtypes:the chemo-sensitive group(CSG)and the chemo-insensitive group(CIG)in the discovery set.The 5-year overall survival of CSG was significantly improved in patients who had received adjuvant chemotherapy after surgery compared with those who received surgery only(64.2%vs.49.6%;Cox P-value=0.002),whereas no such improvement was observed in CIG(50.0%vs.58.6%;Cox P-value=0.495).We validated these results in an independent validation set.Further,differential proteome analysis uncovered 9 FDA-approved drugs that may be applicable for targeted therapy of GC.A prospective study is warranted to test these findings for future GC patient care.

GOLM1 restricts colitis and colon tumorigenesis by ensuring Notch signaling equilibrium in intestinal homeostasis

Intestinal epithelium serves as the first barrier against the infections and injuries that mediate colonic inflammation.Colorectal cancer is often accompanied with chronic inflammation.Differed from its well-known oncogenic role in many malignancies,we present here that Golgi membrane protein 1(G0LM1,also referred to as GP73)suppresses colorectal tumorigenesis via maintenance of intestinal epithelial barrier.G0LM1 deficiency in mice conferred susceptibility to mucosal inflammation and colitis-induced epithelial damage,which consequently promoted colon cancer.Mechanistically,depletion of G0LM1 in intestinal epithelial cells(lECs)led to aberrant Notch activation that interfered with IEC differentiation,maturation,and lineage commitment in mice.Pharmacological inhibition of Notch pathway alleviated epithelial lesions and restrained pro-tumorigenic inflammation in G0LM1-deficient mice.Therefore,G0LM1 maintains IEC homeostasis and protects against colitis and colon tumorigenesis by modulating the equilibrium of Notch signaling pathway.