The gradient porous Ti3Zr2Sn3Mo25Nb(TLM)alloy rods were fabricated through sintering the alloyed powder to a solid core.The porous sample was then modified by a Micro Arc Oxidation(MAO)treatment in an electrolyte cont...The gradient porous Ti3Zr2Sn3Mo25Nb(TLM)alloy rods were fabricated through sintering the alloyed powder to a solid core.The porous sample was then modified by a Micro Arc Oxidation(MAO)treatment in an electrolyte containing calcium and phosphate,a hydrothermal treatment enabled secondary microporous hydroxyapatite(HA)coating,and a further bone morphogenetic protein-2(BMP-2)loading treatment through immersion and freeze-drying.The treatment led to an orderly secondary microporous coating containing HA nano-particles and evenly distributed BMP-2 in the porous coatings.As a result,osteoblasts could adhere and grow well on the coatings with a high cell adhesion rate and cell functional activity.The in-situ shear testing indicated that the interfacial strength had been enhanced significantly.Improvement of the bond formation and osseointegration with the titanium implant is attributed to increased surface area for the cell to attach,creating voids for the cell to grow in,and activating titanium surface by introducing bioactive ingredients such as HA and BMP-2.展开更多
The Chinese civilization is a highly developed,long-standing and comprehensive entity,materially,spiritually and institutionally created by the Chinese nation.Around 6000 BC,Early China in the cultural sense bears its...The Chinese civilization is a highly developed,long-standing and comprehensive entity,materially,spiritually and institutionally created by the Chinese nation.Around 6000 BC,Early China in the cultural sense bears its root,marking the first stage of the origin of Chinese civilization.Around 4000 BC,Early China in the cultural sense formally takes shape,marking the second stage of the origin of Chinese civilization.Around 3100 BC,with the emergence of Chinese civilization,the stage of the Archaic State begins.Around 2100 BC,Early China enters the stage of the Dynastic State.Chinese civilization,with its universalistic cosmology and united structure,is of a unique"Tianxia(all under heaven)civilization"pattern.The"Tianxia civilization"patern,together with other cultural genes such as ritualism,ancestral worship,sincerity,benevolence,and coexistence of all in harmony,is the root cause for the continuous development of Chinese civilization to date.展开更多
基金financial support of the National Natural Science Foundation of China(32071327)National Key Research and Development Program of China(2016YFC1102003)+2 种基金International Science and Technology Cooperation Base of Shaanxi Province(2017GHJD-014)Science and Technology Program of Shaanxi Province(2019GY-200)Key Research and Development Program of Shaanxi Province(2019ZDLSF03-06)。
文摘The gradient porous Ti3Zr2Sn3Mo25Nb(TLM)alloy rods were fabricated through sintering the alloyed powder to a solid core.The porous sample was then modified by a Micro Arc Oxidation(MAO)treatment in an electrolyte containing calcium and phosphate,a hydrothermal treatment enabled secondary microporous hydroxyapatite(HA)coating,and a further bone morphogenetic protein-2(BMP-2)loading treatment through immersion and freeze-drying.The treatment led to an orderly secondary microporous coating containing HA nano-particles and evenly distributed BMP-2 in the porous coatings.As a result,osteoblasts could adhere and grow well on the coatings with a high cell adhesion rate and cell functional activity.The in-situ shear testing indicated that the interfacial strength had been enhanced significantly.Improvement of the bond formation and osseointegration with the titanium implant is attributed to increased surface area for the cell to attach,creating voids for the cell to grow in,and activating titanium surface by introducing bioactive ingredients such as HA and BMP-2.
基金the key project of the National Social Science Foundation"Study on the Civilization Process of Early China from the Eurasian Perspective"(18ZDA172)the key project of Source of China and Songshan Civilization Research Committee in Zhengzhou"The Regional Pattern Study on the Origination of Early Chinese Civilization".
文摘The Chinese civilization is a highly developed,long-standing and comprehensive entity,materially,spiritually and institutionally created by the Chinese nation.Around 6000 BC,Early China in the cultural sense bears its root,marking the first stage of the origin of Chinese civilization.Around 4000 BC,Early China in the cultural sense formally takes shape,marking the second stage of the origin of Chinese civilization.Around 3100 BC,with the emergence of Chinese civilization,the stage of the Archaic State begins.Around 2100 BC,Early China enters the stage of the Dynastic State.Chinese civilization,with its universalistic cosmology and united structure,is of a unique"Tianxia(all under heaven)civilization"pattern.The"Tianxia civilization"patern,together with other cultural genes such as ritualism,ancestral worship,sincerity,benevolence,and coexistence of all in harmony,is the root cause for the continuous development of Chinese civilization to date.
