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Stress Hyperglycemia:A Problem that Cannot be Ignored
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作者 Daxu Peng Yifan Zhang +1 位作者 Xiuyang Cao jianyi pu 《Journal of Endocrinology Research》 2022年第1期1-7,共7页
Stress hyperglycemia is a strong neuroendocrine reaction in the hypothalamic pituitary adrenal cortex under severe infection,trauma,burns,hemorrhage,surgery and other harmful stimulated,resulting in increased secretio... Stress hyperglycemia is a strong neuroendocrine reaction in the hypothalamic pituitary adrenal cortex under severe infection,trauma,burns,hemorrhage,surgery and other harmful stimulated,resulting in increased secretion of counter-regulatory hormones.These hormones promoted the production of sugar and cause glucose metabolism disorders with cytokines and insulin resistance.In this condition,the production of sugar exceeds the utilization of sugar by the tissues,which eventually leads to an increase in blood glucose levels in plasma.In the intensive care unit,stress hyperglycemia is very common and can occur in patients with or without diabetes.The incidence is as high as 96%,and it is an independent factor in the death of critically ill patients.Hyperglycemia not only prolongs the hospitalization time,mechanical ventilation time and increased the incidence of serious infections in critically ill patients,but can also lead to the occurrence of type 2 diabetes.Therefore,it is very important to learn the pathological mechanism of stress hyperglycemia,the harm of hyperglycemia and blood sugar management. 展开更多
关键词 Isletβcells HYPERGLYCEMIA Insulin resistance Critical illness Intensive care
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