Objective: To analyze the application value of psychological intervention in gastric cancer nursing. Methods: This study analyzes gastric cancer patients admitted to hospitals from May 2022 to May 2023. Based on resea...Objective: To analyze the application value of psychological intervention in gastric cancer nursing. Methods: This study analyzes gastric cancer patients admitted to hospitals from May 2022 to May 2023. Based on research requirements and patient willingness, 80 patients were selected and divided into observation and control groups using a lottery method. The control group received conventional nursing care, while the observation group received psychological intervention in addition to conventional nursing care. Results: After the psychological intervention, patients in the observation group showed significant improvements in anxiety and depression, better sleep quality, remarkable enhancement in psychological resilience, higher levels of health literacy, and increased nursing satisfaction compared to the control group (P < 0.05). Conclusion: Incorporating psychological intervention into the nursing care of gastric cancer patients enhances their psychological adjustment ability and improves treatment adherence.展开更多
Mitochondrial protein translation that is essential for aerobic energy production includes four essential steps of the mitochondrial ribosome cycle,namely,initiation,elongation,termination of the polypeptide,and ribos...Mitochondrial protein translation that is essential for aerobic energy production includes four essential steps of the mitochondrial ribosome cycle,namely,initiation,elongation,termination of the polypeptide,and ribosome recycling.Translation termination initiates when a stop codon enters the A site of the mitochondrial ribosome where it is recognized by a dedicated peptide release factor(RF).However,RFs and mechanisms involved in translation in plant mitochondria,especially in monocotyledons,remain largely unknown.Here,we identified a crumpled kernel(crk5 allele)mutant,with significantly decreased kernel size,100-kernel weight,and an embryo-lethal phenotype.The Crk5 allele was isolated using map-based cloning and found to encode a mitochondrial localization RF2a.As it is an ortholog of Arabidopsis mitochondrial RF2a,we named the gene ZmmtRF2a.ZmmtRF2a is missing the 5th–7th exons in the crk5 resulting in deletion of domains containing motifs GGQ and SPF that are essential for release activity of RF,mitochondrial ribosome binding,and stop codon recognition.Western blot and qRT-PCR analyses indicate that the crk5 mutation results in abnormal mitochondrion structure and function.Intriguingly,we observed a feedback loop in the crk5 with up-regulated transcript levels detected for several mitochondrial ribosome and mitochondrial-related components,in particular mitochondrial complexes CI,CIV,and a ribosome assembly related PPR.Together,our data support a crucial role for ZmmtRF2a in regulation of mitochondrial structure and function in maize.展开更多
目的分析本地妊娠晚期妇女B族链球菌(group B Streptococcus,GBS)的定植率与药敏情况,以指导临床制定合适的筛查与预防策略。方法通过回顾性的研究,以山东省妇幼保健院2019年1月至2020年12月进行孕晚期B组链球菌筛选的孕妇为研究对象,...目的分析本地妊娠晚期妇女B族链球菌(group B Streptococcus,GBS)的定植率与药敏情况,以指导临床制定合适的筛查与预防策略。方法通过回顾性的研究,以山东省妇幼保健院2019年1月至2020年12月进行孕晚期B组链球菌筛选的孕妇为研究对象,共纳入6 345名孕妇,分别取肛门拭子和阴道拭子进行培养、鉴定及药敏试验,统计分析B族链球菌带菌与药敏状况。结果本地区妊娠晚期妇女B族链球菌阳性率7.2%,低于发达国家报道的14%~30%,与中国其他地区的定植率也存在一定的差异;阴道拭子检出率是3.9%,直肠拭子检出率是5.5%,两者较综合检出率低,差异有统计学意义(P<0.05);31~35岁组带菌率最高7.70%,与其他各年龄比较差异均无统计学意义(P>0.05);本地区B族链球菌对青霉素、阿莫西林、利奈唑胺、美罗培南、头孢吡肟、头孢噻肟和万古霉素的敏感率为100%,对红霉素、克林霉素、氯霉素、四环素和左氧氟沙星的敏感率分别是21%、32.5%、89.5%、70.2%、31.5%。结论不同地区孕产期妇女B族链球菌带菌率存在差异,各年龄组之间无明显差异,同时送检阴道和直肠拭子可以提高检出率,青霉素仍可作为预防B族链球菌感染的首选药物,对青霉素过敏者建议进行药敏试验。展开更多
In recent years,the temperature-adjusted asphalt pavement has been an extensive concern by scholars in various countries,and this pavement can reduce temperaturerelated diseases.In this study,the shaped composite phas...In recent years,the temperature-adjusted asphalt pavement has been an extensive concern by scholars in various countries,and this pavement can reduce temperaturerelated diseases.In this study,the shaped composite phase change materials(CPCMs)were successfully synthesized by two processes,which are vacuum impregnation and epoxy curing.Firstly,the applicability of CPCMs in asphalt mixtures was evaluated by microscopic characterization,chemical compatibility,thermal properties,durability,and leakage stability.Secondly,CPCMs were applied to the asphalt mixture to evaluate its temperatureadjusted characteristics and pavement performance.Finally,the performance of the temperature-adjusted asphalt mixture was analyzed by integrating all factors.The research shows that the prepared CPCMs have excellent thermal properties and durability,the phase transition temperature is 48.93℃,and the phase transition enthalpy is 106.5 J/g,which fully meets the requirements for use in pavement.The temperature-adjusted asphalt mixture could alleviate the occurrence of extreme temperature,which was 4.9℃lower than the conventional mixture.The pavement performance of the temperatureadjusted asphalt mixture can meet the specified standards for humid areas.Considering the factors,the recommended amount of CPCMs is 1.5%.The research results provide a basis for the promotion of temperature-adjusted asphalt pavement and effectively support the development of pavement engineering technology.展开更多
文摘Objective: To analyze the application value of psychological intervention in gastric cancer nursing. Methods: This study analyzes gastric cancer patients admitted to hospitals from May 2022 to May 2023. Based on research requirements and patient willingness, 80 patients were selected and divided into observation and control groups using a lottery method. The control group received conventional nursing care, while the observation group received psychological intervention in addition to conventional nursing care. Results: After the psychological intervention, patients in the observation group showed significant improvements in anxiety and depression, better sleep quality, remarkable enhancement in psychological resilience, higher levels of health literacy, and increased nursing satisfaction compared to the control group (P < 0.05). Conclusion: Incorporating psychological intervention into the nursing care of gastric cancer patients enhances their psychological adjustment ability and improves treatment adherence.
基金the National Natural Science Foundation of China(31971893,U2004144)the Key Technologies R&D Program of Henan Province(232102111080,212102110043)Academician Expert Workstation(202305AF150082).
文摘Mitochondrial protein translation that is essential for aerobic energy production includes four essential steps of the mitochondrial ribosome cycle,namely,initiation,elongation,termination of the polypeptide,and ribosome recycling.Translation termination initiates when a stop codon enters the A site of the mitochondrial ribosome where it is recognized by a dedicated peptide release factor(RF).However,RFs and mechanisms involved in translation in plant mitochondria,especially in monocotyledons,remain largely unknown.Here,we identified a crumpled kernel(crk5 allele)mutant,with significantly decreased kernel size,100-kernel weight,and an embryo-lethal phenotype.The Crk5 allele was isolated using map-based cloning and found to encode a mitochondrial localization RF2a.As it is an ortholog of Arabidopsis mitochondrial RF2a,we named the gene ZmmtRF2a.ZmmtRF2a is missing the 5th–7th exons in the crk5 resulting in deletion of domains containing motifs GGQ and SPF that are essential for release activity of RF,mitochondrial ribosome binding,and stop codon recognition.Western blot and qRT-PCR analyses indicate that the crk5 mutation results in abnormal mitochondrion structure and function.Intriguingly,we observed a feedback loop in the crk5 with up-regulated transcript levels detected for several mitochondrial ribosome and mitochondrial-related components,in particular mitochondrial complexes CI,CIV,and a ribosome assembly related PPR.Together,our data support a crucial role for ZmmtRF2a in regulation of mitochondrial structure and function in maize.
文摘目的分析本地妊娠晚期妇女B族链球菌(group B Streptococcus,GBS)的定植率与药敏情况,以指导临床制定合适的筛查与预防策略。方法通过回顾性的研究,以山东省妇幼保健院2019年1月至2020年12月进行孕晚期B组链球菌筛选的孕妇为研究对象,共纳入6 345名孕妇,分别取肛门拭子和阴道拭子进行培养、鉴定及药敏试验,统计分析B族链球菌带菌与药敏状况。结果本地区妊娠晚期妇女B族链球菌阳性率7.2%,低于发达国家报道的14%~30%,与中国其他地区的定植率也存在一定的差异;阴道拭子检出率是3.9%,直肠拭子检出率是5.5%,两者较综合检出率低,差异有统计学意义(P<0.05);31~35岁组带菌率最高7.70%,与其他各年龄比较差异均无统计学意义(P>0.05);本地区B族链球菌对青霉素、阿莫西林、利奈唑胺、美罗培南、头孢吡肟、头孢噻肟和万古霉素的敏感率为100%,对红霉素、克林霉素、氯霉素、四环素和左氧氟沙星的敏感率分别是21%、32.5%、89.5%、70.2%、31.5%。结论不同地区孕产期妇女B族链球菌带菌率存在差异,各年龄组之间无明显差异,同时送检阴道和直肠拭子可以提高检出率,青霉素仍可作为预防B族链球菌感染的首选药物,对青霉素过敏者建议进行药敏试验。
基金supported by the National Natural Science Foundation of China(52174237,51704040)Science Foundation for Outstanding Youth of Hunan Province(2022JJ10051)+3 种基金Excellent Early Career Scientists from Germany(GZ1717)Science and Technology Project of Changsha-Outstanding Innovative Youth(kq2305020)Guangdong Provincial Key Laboratory of Modern Civil Engineering Technology(2021B1212040003)Postgraduate Scientific Research Innovation Project of Hunan Province(CX20230851,QL20230205)。
文摘In recent years,the temperature-adjusted asphalt pavement has been an extensive concern by scholars in various countries,and this pavement can reduce temperaturerelated diseases.In this study,the shaped composite phase change materials(CPCMs)were successfully synthesized by two processes,which are vacuum impregnation and epoxy curing.Firstly,the applicability of CPCMs in asphalt mixtures was evaluated by microscopic characterization,chemical compatibility,thermal properties,durability,and leakage stability.Secondly,CPCMs were applied to the asphalt mixture to evaluate its temperatureadjusted characteristics and pavement performance.Finally,the performance of the temperature-adjusted asphalt mixture was analyzed by integrating all factors.The research shows that the prepared CPCMs have excellent thermal properties and durability,the phase transition temperature is 48.93℃,and the phase transition enthalpy is 106.5 J/g,which fully meets the requirements for use in pavement.The temperature-adjusted asphalt mixture could alleviate the occurrence of extreme temperature,which was 4.9℃lower than the conventional mixture.The pavement performance of the temperatureadjusted asphalt mixture can meet the specified standards for humid areas.Considering the factors,the recommended amount of CPCMs is 1.5%.The research results provide a basis for the promotion of temperature-adjusted asphalt pavement and effectively support the development of pavement engineering technology.
