Since the end of 2019,COVID-19 has caused worldwide pandemic.SARS-CoV-2,the culprit of this epidemic,binds to the host receptor Angiotensin converting enzyme 2(ACE2)using spike(S)protein for cell entry.Recent studies ...Since the end of 2019,COVID-19 has caused worldwide pandemic.SARS-CoV-2,the culprit of this epidemic,binds to the host receptor Angiotensin converting enzyme 2(ACE2)using spike(S)protein for cell entry.Recent studies showed that ACE2 expressed at a low level in the main target organs such as lung and bronchial tissues.How SARS-CoV-2 efficiently invades into the respiratory system or other organs with low levels of ACE2 is an urgent problem to be solved.展开更多
基金supported by Clinical Research Cultivation Project of First Affiliated Hospital of Nanchang University(China)(No.YFYLCYJPY202001).
文摘Since the end of 2019,COVID-19 has caused worldwide pandemic.SARS-CoV-2,the culprit of this epidemic,binds to the host receptor Angiotensin converting enzyme 2(ACE2)using spike(S)protein for cell entry.Recent studies showed that ACE2 expressed at a low level in the main target organs such as lung and bronchial tissues.How SARS-CoV-2 efficiently invades into the respiratory system or other organs with low levels of ACE2 is an urgent problem to be solved.
