Analysis of Combined Natural Convection and Radiation Heat Transfer in a Partitioned Rectangular Enclosure with Semitransparent Walls

In this paper, we present a two-dimensional numerical analysis of the conjugate natural convection and radiation heat transfer in a double-space enclosure with two semitransparent walls. Two kinds of boundary conditions are considered, the rst being the isothermal process of the opaque wall, and the other the incidence of a constant radiation ux in the left semitransparent wall. The renormalization group k ε model is adopted to simulate the turbulent ow in the enclosure. To compute the radia- tion heat transfer in a semitransparent medium, the discrete ordinates model is used. We compare the behaviors of enclosures with single and double semitransparent walls and determine the di erence in the results obtained for semitransparent and opaque partitions. The results indicate that a semitransparent partition facilitates a reduction in the heat loss or obtains a higher temperature distribution. The transmittance of a semitransparent wall has a great e ect on the thermal and ow char- acteristics in an enclosure. The change of wall temperature is found to be signi cant when the thermal conductivity values range from 0.05 to 0.5 W/(m K), and to be small when ranging from 0.5 to 10 W/(m K). These conclusions are helpful for green design and energy saving in solar buildings.

Editorial for Special Issue on Artificial Intelligence for Art

As an innovative engine for digital content generation,AI-generated content(AIGC)has drawn more and more attention from academic fields as well as industries.Specifically in the area of art creation,AI has demonstrated its great potential and gained increasing popularity.People are greatly impressed by AI painting,composing,writing,virtual hosting,fashion,and design.Moreover,AI is also becoming capable of understanding art,evaluating the aesthetic value of art,and protecting the copyright of art as well.AI has not only exhibited creativity to some extent,but also served as an enabling tool to discover the principles underneath creativity and imagination,which are traditional challenges for neuroscience,cognitive science,and psychology.Despite all these promising features of AI for art,we still have to face the many challenges such as the explainability of generative models and the copyright issues of AI art works.

Activation of Pancreatic Acinar FXR Protects against Pancreatitis via Osginl-Mediated Restoration of Efficient Autophagy

Pancreatitis is the leading cause of hospitalization in gastroenterology,and no medications are available for treating this disease in current clinical practice.FxR plays an anti-inflammatory role in diverse inflammatory diseases,while its function in pancreatitis remains unknown.In this study,we initially observed a marked increase of nuclear FXR in pancreatic tissues of human patients ithpancratis eleting theFXRinpancreati acinar cels FXRicnara/a)ledto moreseverepancreatitis in mousemodels of caerulein-induced acute and chronic pancreatitis,while the FXR agonist GW4064 significantly attenuated pancreatitis in caerulein or arginine-induced acute pancreatitis and caerulein-induced chronic pancreatitis.FXR deletion impaired the viability and stress responses of pancreatic exocrine organoids(PEOs)in vitro.Utilizing RNA-seq and ChIP-seq of PEOs,we identified Osginl as a direct target of FxR in the exocrine pancreas,which was also increasingly expressed in human pancreatitis tissues compared to normal pancreatic tissues.Pancreatic knockdown of Osgin1 by AAV-pan abolished the therapeutic effects of FXR activation on pancreatitis,whereas pancreatic overexpression of Osginl effectively alleviated caerulein-induced pancreatitis.Mechanistically,we found that the FXR-OSGINl axis stimulated autophagic flux in the pancreatic tissues and cell lines,which was considered as the intrinsic mechanisms through which FXR-OSGINI protecting against pancreatitis.Our results highlight the protective role of the FXR-OSGIN1 axis in pancreatitis and provided a new target for the treatment of this disease.

Exposure to Emerging and Legacy Polyfluoroalkyl Substances in the Sixth Total Diet Study-China,2016-2019

Summary What is already known about this topic?Perfluoroalkyl substances(PFASs)are persistent organic pollutants,which have multi-organ toxicity and potential health risk to humans.What is added by this report?The most commonly detected PFASs in the Sixth China Total Diet Study(TDS)samples were perfluorooctanesulfonate(PFOS),perfluorooctanoic acid(PFOA),perfluoroundecanoic acid(PFUdA),perfluorodecanoic acid(PFDA),perfluorononanoic acid(PFNA),and 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate(6:2 Cl-PFESA).The mean estimated weekly intakes(EWIs)of PFOA,PFOS,and 6:2 Cl-PFESA in the Sixth TDS were 2.17,2.72,and 2.75 ng/kg body weight per week,respectively.What are the implications for public health practice?The PFASs levels in some food category and dietary exposure still need to be continuously monitored,especially for 6:2 Cl-PFESA.

Moire-pattern-modulated electronic structures in Sb_(2)Te_(3)/graphene heterostructure

Moire superlattice has recently been found in topological insulators,which can lead to periodic modulation on the electronic structure.In this work,we report the low-temperature scanning tunneling microscopy study of Sb_(2)Te_(3) films grown on graphitized 4H-SiC.We find that substrate temperature can strongly influence the rotation angles between Sb_(2)Te_(3) film and graphene substrate.Three kinds of moire patterns are observed at the first quintuple layer Sb_(2)Te_(3) film under different substrate temperatures.One shows complicated patterns with a rotation angle of nearly 0°relative to the substrate,another just exhibits simple 1 ×1 structure with a rotation angle of 30°.Other rotation angle like 8.2°is observed at higher substrate temperature as well,which is relatively rare.Comparison of the d//dV curves from Sb_(2)Te_(3) films with different moire patterns indicates that the superstructure can offer degrees of freedom in tailoring electronic structure.This work may stimulate the further study on the moire modulation to the electronic properties of topological insulators.

经皮穿刺椎体成形术后应用唑来膦酸钠的疗效观察

目的了解唑来膦酸钠对经皮穿刺椎体成形术(PVP)术后残余疼痛、胸腰椎小关节紊乱及再发骨折的作用。方法收集2020年7月至2021年7月在佛山健翔骨伤医院骨科诊断为骨质疏松性椎体压缩性骨折(OVCF),并行PVP的患者60名,排除爆裂骨折等其他损伤和激素使用史、肝肾功能障碍及其他严重疾病。依据随机数字表法分为对照组(30名)、治疗组(30名)。对照组给予维生素D_(2)+钙剂治疗1年;治疗组给予唑来膦酸钠(1次/年)+维生素D_(2)+钙剂治疗1年。收集两组患者视觉模拟评分、功能障碍评分、胸腰椎小关节紊乱诱发疼痛发生率、骨密度和血清骨代谢指标,并采用独立样本t检验、重复测量方差分析及卡方检验进行统计学处理。结果与对照组比较,治疗组的视觉模拟评分(t=2.867、3.090)、功能障碍评分(t=2.732、2.277)在治疗后3个月、治疗后1年均有改善(均为P<0.05)。与对照组相比,治疗组治疗后1年胸腰椎小关节紊乱诱发复发性疼痛的发生率明显降低(χ^(2)=4.8,P<0.05)。与治疗前相比,治疗组在治疗后1年对骨密度的促进作用有统计学意义(t=-2.723,P<0.05)。与对照组相比,治疗组在治疗后3个月、治疗后1年对β-异构C-端肽(β-CTX)的抑制作用有统计学意义(t=4.687、2.952,均为P<0.05),对Ⅰ型前胶原氨基末端(N端)前肽(PINP)、2,5(OH)VitD的促进作用无统计学意义(均为P>0.05)。对照组与治疗组在治疗后1年PINP较治疗前下降(F=5.697、6.974,均为P<0.05),但治疗组优于对照组;治疗组在治疗后3个月及治疗后1年β-CTX则较治疗前降低(F=7.036、5.381,均为P<0.05);对照组在治疗后3个月2,5(OH)VitD则较治疗前上升(F=5.915,P<0.05),治疗后1年较治疗前明显上升(F=11.690,P<0.01);治疗组在治疗后3个月及治疗后1年2,5(OH)VitD较治疗前明显上升(F=10.354、11.935,均为P<0.01)。结论唑来膦酸钠可以改善骨质疏松性椎体压缩性骨折患者PVP术后疼痛程度及功能障碍,降低胸腰椎小关节紊乱诱发疼痛发生率,提高患者骨密度水平,明显降低椎体再发骨折风险。