Carbyne delivers various excellent properties for the existence of the larger number of sp-hybridized carbon atoms.Here,a 3D well-defined porous carbon material germanium-carbdiyne(Ge-CDY)which is comprised of only sp...Carbyne delivers various excellent properties for the existence of the larger number of sp-hybridized carbon atoms.Here,a 3D well-defined porous carbon material germanium-carbdiyne(Ge-CDY)which is comprised of only sp-hybridized carbon atoms bridging by Ge atoms has been developed and investigated.The unique diamond-like structure constructed by linear butadiyne bonds and sp 3-hybridized Ge atoms ensures the stability of Ge-CDY.The large percentage of conjugated alkyne bonds composed of sp-C guarantees the good conductivity and the low band gap,which were further confirmed experimentally and theoretically,endowing Ge-CDY with the potential in electrochemical applications.The well-defined 3D carbon skeleton of Ge-CDY provides abundant uniform nanopores,which is suitable for metal ions storage and diffusion.Further half-cell evaluation also demonstrated Ge-CDY exhibited an excellent performance in lithium storage.All those indicating sp-hybridized carbon-based materials can exhibit great potential to possess excellent properties and be applied in the field of energy,electronic,and so on.展开更多
Lithospermoside is a kind of alkaloid compound existing in Semiaquilegia adoxoides,with anticancer,anti-inflammatory,antibacterial,hypoglycemic,antioxidant and other pharmacological effects.This paper reviews the phar...Lithospermoside is a kind of alkaloid compound existing in Semiaquilegia adoxoides,with anticancer,anti-inflammatory,antibacterial,hypoglycemic,antioxidant and other pharmacological effects.This paper reviews the pharmacological action and molecular mechanism of lithospermoside,in order to provide a theoretical basis for clinical application of lithospermoside.展开更多
Cannabidiol(CBD)is the active constituent of Cannabis sativa and exhibits a diverse range of pharmacologic effects,including anticancer,antibacterial,anti-inflammatory,antioxidant,and antiepileptic properties.The phar...Cannabidiol(CBD)is the active constituent of Cannabis sativa and exhibits a diverse range of pharmacologic effects,including anticancer,antibacterial,anti-inflammatory,antioxidant,and antiepileptic properties.The pharmacologic effects of CBD and its molecular mechanisms are reviewed with the objective of proposing novel approaches for basic research and clinical applications of CBD and related pharmaceuticals.展开更多
Extensive studies have found that Esculentoside a(EsA)has a variety of pharmacological effects,such as anti-inflammatory,anti-bacterial,anti-tumor and the treatment of arthritis.In the present paper,the pharmacologica...Extensive studies have found that Esculentoside a(EsA)has a variety of pharmacological effects,such as anti-inflammatory,anti-bacterial,anti-tumor and the treatment of arthritis.In the present paper,the pharmacological effects and related mechanisms of EsA in recent years were reviewed,in order to provide a theoretical reference for further research and development of EsA.展开更多
Dendrobine,an alkaloid extracted from the stem of Dendrobium nobile Lindl.,has many biological activities such as anti-cancer effect,anti-inflammation effect,anti-influenza A virus effect,treatment of leukemia,treatme...Dendrobine,an alkaloid extracted from the stem of Dendrobium nobile Lindl.,has many biological activities such as anti-cancer effect,anti-inflammation effect,anti-influenza A virus effect,treatment of leukemia,treatment of Parkinson s disease,protection of internal organs and promotion of cell maturation.In this paper,the related research progress of pharmacological action and molecular mechanism of dendrobine will be reviewed in order to provide a theoretical basis for further research and drug development of dendrobine.展开更多
Aloin is the main medicinal component extracted from Aloe vera.It is a natural anthraquinone compound,with anticancer,anti-inflammatory and antibacterial and other biological functions.This paper reviews the pharmacol...Aloin is the main medicinal component extracted from Aloe vera.It is a natural anthraquinone compound,with anticancer,anti-inflammatory and antibacterial and other biological functions.This paper reviews the pharmacological action and related mechanisms of aloin,in order to provide a theoretical basis for the development and utilization of aloin.展开更多
The formulation of hard chromium plating from trivalent chromium electrolyte and its related process have been intensively studied in this work. Through optimized conditions, the coating hardness can achieve more than...The formulation of hard chromium plating from trivalent chromium electrolyte and its related process have been intensively studied in this work. Through optimized conditions, the coating hardness can achieve more than HV0.1900 without any treatment and HV0.11700 after heat treatment for five minutes at 300°C, and the thickness of hard chromium coating was about 100 μm. The hard chromium coatings show good adhesion on the carbon steel and low alloy structural steel. The corrosion resistance of hard chromium coatings was enhanced by the adding nanometer materials into trivalent chromium plating coatings. More than 120 hours salt spray corrosion resistance can be achieved with 40 to 50 microns thickness of trivalent chromium plating coatings.展开更多
Crotonoside is an important alkaloid component in Croton tiglium.It has the effects of drastic purgation,expelling water and reducing swelling,eliminating phlegm and relieving pharynx.Studies have found that crotonosi...Crotonoside is an important alkaloid component in Croton tiglium.It has the effects of drastic purgation,expelling water and reducing swelling,eliminating phlegm and relieving pharynx.Studies have found that crotonoside can exert a variety of pharmacological effects such as anti-cancer,anti-inflammatory,anti-arrhythmic,and anti-acute myelogenous leukemia through a variety of ways.This paper reviewed the pharmacological effects and mechanisms of crotonoside.展开更多
5-O-methylvisammioside is a chemical derived from the dry root of Saposhnikovia divaricata,which has the functions of expelling pathogenic wind from body surface,removing dampness to relieve pain,and relieving convuls...5-O-methylvisammioside is a chemical derived from the dry root of Saposhnikovia divaricata,which has the functions of expelling pathogenic wind from body surface,removing dampness to relieve pain,and relieving convulsion.Recent studies have found that 5-O-methylvisammioside can play a variety of pharmacological effects such as anti-tumor,anti-inflammation,anti-virus and anti-depression through a variety of ways.The paper reviews the pharmacological action and mechanism of 5-O-methylvisammioside in recent years.展开更多
Harmaine hydrochloride is an important alkaloid compound and mainly exists in the roots,stems,leaves and seeds of the plant Peganum harmala L.(family Zygophyllaceae).Harmaine hydrochloride not only has good anti-bacte...Harmaine hydrochloride is an important alkaloid compound and mainly exists in the roots,stems,leaves and seeds of the plant Peganum harmala L.(family Zygophyllaceae).Harmaine hydrochloride not only has good anti-bacterial,anti-plasmodium,anti-Parkinson's disease,anti-fungal,anti-oxidation and anti-tumor activities,but also has the characteristics of small adverse reactions and low toxicity,thus it has attracted wide attention from scholars and researchers.This paper reviews the pharmacological effects and mechanisms of harmine hydrochloride in recent years,and is intended to provide a theoretical basis for the clinical application of harmine hydrochloride.展开更多
Pipe contaminant detection holds considerable importance within various industries,such as the aviation,maritime,medicine,and other pertinent fields.This capability is beneficial for forecasting equipment potential fa...Pipe contaminant detection holds considerable importance within various industries,such as the aviation,maritime,medicine,and other pertinent fields.This capability is beneficial for forecasting equipment potential failures,ascertaining operational situations,timely maintenance,and lifespan prediction.However,the majority of existing methods operate offline,and the detectable parameters online are relatively singular.This constraint hampers real-time on-site detection and comprehensive assessments of equipment status.To address these challenges,this paper proposes a sensing method that integrates an ultrasonic unit and an electromagnetic inductive unit for the real-time detection of diverse contaminants and flow rates within a pipeline.The ultrasonic unit comprises a flexible transducer patch fabricated through micromachining technology,which can not only make installation easier but also focus the sound field.Moreover,the sensing unit incorporates three symmetrical solenoid coils.Through a comprehensive analysis of ultrasonic and induction signals,the proposed method can be used to effectively discriminate magnetic metal particles(e.g.,iron),nonmagnetic metal particles(e.g.,copper),nonmetallic particles(e.g.,ceramics),and bubbles.This inclusive categorization encompasses nearly all types of contaminants that may be present in a pipeline.Furthermore,the fluid velocity can be determined through the ultrasonic Doppler frequency shift.The efficacy of the proposed detection principle has been validated by mathematical models and finite element simulations.Various contaminants with diverse velocities were systematically tested within a 14mm diameter pipe.The experimental results demonstrate that the proposed sensor can effectively detect contaminants within the 0.5−3mm range,accurately distinguish contaminant types,and measure flow velocity.展开更多
基金This study was supported by the National Natural Science Foundation of China (21701182,51822208,21771187,21790050,and 21790051)the Frontier Science Research Project (QYZDB-SSW-JSC052)+1 种基金the Chinese Academy of Sciences,the Taishan Scholars Program of Shandong Province (tsqn201812111)Institute Research Project (QIBEBT ZZBS 201809).
文摘Carbyne delivers various excellent properties for the existence of the larger number of sp-hybridized carbon atoms.Here,a 3D well-defined porous carbon material germanium-carbdiyne(Ge-CDY)which is comprised of only sp-hybridized carbon atoms bridging by Ge atoms has been developed and investigated.The unique diamond-like structure constructed by linear butadiyne bonds and sp 3-hybridized Ge atoms ensures the stability of Ge-CDY.The large percentage of conjugated alkyne bonds composed of sp-C guarantees the good conductivity and the low band gap,which were further confirmed experimentally and theoretically,endowing Ge-CDY with the potential in electrochemical applications.The well-defined 3D carbon skeleton of Ge-CDY provides abundant uniform nanopores,which is suitable for metal ions storage and diffusion.Further half-cell evaluation also demonstrated Ge-CDY exhibited an excellent performance in lithium storage.All those indicating sp-hybridized carbon-based materials can exhibit great potential to possess excellent properties and be applied in the field of energy,electronic,and so on.
基金Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16)Heilongjiang Provincial Key Research and Development Plan Guidance Project(GZ20220039)Postgraduate Innovative Research Project of Heilongjiang Bayi Agricultural University(YJSCX2022-Y55).
文摘Lithospermoside is a kind of alkaloid compound existing in Semiaquilegia adoxoides,with anticancer,anti-inflammatory,antibacterial,hypoglycemic,antioxidant and other pharmacological effects.This paper reviews the pharmacological action and molecular mechanism of lithospermoside,in order to provide a theoretical basis for clinical application of lithospermoside.
基金Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16)Heilongjiang Provincial Key Research and Development Plan Guidance Project(GZ20220039).
文摘Cannabidiol(CBD)is the active constituent of Cannabis sativa and exhibits a diverse range of pharmacologic effects,including anticancer,antibacterial,anti-inflammatory,antioxidant,and antiepileptic properties.The pharmacologic effects of CBD and its molecular mechanisms are reviewed with the objective of proposing novel approaches for basic research and clinical applications of CBD and related pharmaceuticals.
基金Central Talent Training Project for the Reform and Development of Local Colleges and Universities(2020GSP16)Guidance Project of Key R&D Plan in Heilongjiang Province(GZ20220039).
文摘Extensive studies have found that Esculentoside a(EsA)has a variety of pharmacological effects,such as anti-inflammatory,anti-bacterial,anti-tumor and the treatment of arthritis.In the present paper,the pharmacological effects and related mechanisms of EsA in recent years were reviewed,in order to provide a theoretical reference for further research and development of EsA.
基金Supported by The Central Talent Training Project for Local University Reform and Development(2020GSP16)Guidance Project of Key R&D Plan in Heilongjiang Province(GZ20220039)Innovative Research Project for Postgraduates of Heilongjiang Bayi Agricultural University(YJSCX2022-Y55).
文摘Dendrobine,an alkaloid extracted from the stem of Dendrobium nobile Lindl.,has many biological activities such as anti-cancer effect,anti-inflammation effect,anti-influenza A virus effect,treatment of leukemia,treatment of Parkinson s disease,protection of internal organs and promotion of cell maturation.In this paper,the related research progress of pharmacological action and molecular mechanism of dendrobine will be reviewed in order to provide a theoretical basis for further research and drug development of dendrobine.
基金Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16)Heilongjiang Provincial Key Research and Development Plan Guidance Project(GZ20220039)Postgraduate Innovative Research Project of Heilongjiang Bayi Agricultural University(YJSCX2022-Y55).
文摘Aloin is the main medicinal component extracted from Aloe vera.It is a natural anthraquinone compound,with anticancer,anti-inflammatory and antibacterial and other biological functions.This paper reviews the pharmacological action and related mechanisms of aloin,in order to provide a theoretical basis for the development and utilization of aloin.
文摘The formulation of hard chromium plating from trivalent chromium electrolyte and its related process have been intensively studied in this work. Through optimized conditions, the coating hardness can achieve more than HV0.1900 without any treatment and HV0.11700 after heat treatment for five minutes at 300°C, and the thickness of hard chromium coating was about 100 μm. The hard chromium coatings show good adhesion on the carbon steel and low alloy structural steel. The corrosion resistance of hard chromium coatings was enhanced by the adding nanometer materials into trivalent chromium plating coatings. More than 120 hours salt spray corrosion resistance can be achieved with 40 to 50 microns thickness of trivalent chromium plating coatings.
基金Innovation and Entrepreneurship Project of College Students(202010223001,202010223004).
文摘Crotonoside is an important alkaloid component in Croton tiglium.It has the effects of drastic purgation,expelling water and reducing swelling,eliminating phlegm and relieving pharynx.Studies have found that crotonoside can exert a variety of pharmacological effects such as anti-cancer,anti-inflammatory,anti-arrhythmic,and anti-acute myelogenous leukemia through a variety of ways.This paper reviewed the pharmacological effects and mechanisms of crotonoside.
基金Supported by Talent Training Program of Central Fund for Supporting the Reform and Development of Local Colleges and Universities(2020GSP16).
文摘5-O-methylvisammioside is a chemical derived from the dry root of Saposhnikovia divaricata,which has the functions of expelling pathogenic wind from body surface,removing dampness to relieve pain,and relieving convulsion.Recent studies have found that 5-O-methylvisammioside can play a variety of pharmacological effects such as anti-tumor,anti-inflammation,anti-virus and anti-depression through a variety of ways.The paper reviews the pharmacological action and mechanism of 5-O-methylvisammioside in recent years.
基金Central Government Supporting Local University Reform and Development Fund Talent Training Project(2020GSP16).
文摘Harmaine hydrochloride is an important alkaloid compound and mainly exists in the roots,stems,leaves and seeds of the plant Peganum harmala L.(family Zygophyllaceae).Harmaine hydrochloride not only has good anti-bacterial,anti-plasmodium,anti-Parkinson's disease,anti-fungal,anti-oxidation and anti-tumor activities,but also has the characteristics of small adverse reactions and low toxicity,thus it has attracted wide attention from scholars and researchers.This paper reviews the pharmacological effects and mechanisms of harmine hydrochloride in recent years,and is intended to provide a theoretical basis for the clinical application of harmine hydrochloride.
基金supported in part by the National Key Research and Development Program(2022YFB3205400)the National Natural Science Foundation of China(52275570)+1 种基金the Major Science and Technology Project of Anhui Province(2022e03020002)the Shaanxi Province Qin Chuangyuan“Scientist+Engineer”Team(2022KXJ-02).
文摘Pipe contaminant detection holds considerable importance within various industries,such as the aviation,maritime,medicine,and other pertinent fields.This capability is beneficial for forecasting equipment potential failures,ascertaining operational situations,timely maintenance,and lifespan prediction.However,the majority of existing methods operate offline,and the detectable parameters online are relatively singular.This constraint hampers real-time on-site detection and comprehensive assessments of equipment status.To address these challenges,this paper proposes a sensing method that integrates an ultrasonic unit and an electromagnetic inductive unit for the real-time detection of diverse contaminants and flow rates within a pipeline.The ultrasonic unit comprises a flexible transducer patch fabricated through micromachining technology,which can not only make installation easier but also focus the sound field.Moreover,the sensing unit incorporates three symmetrical solenoid coils.Through a comprehensive analysis of ultrasonic and induction signals,the proposed method can be used to effectively discriminate magnetic metal particles(e.g.,iron),nonmagnetic metal particles(e.g.,copper),nonmetallic particles(e.g.,ceramics),and bubbles.This inclusive categorization encompasses nearly all types of contaminants that may be present in a pipeline.Furthermore,the fluid velocity can be determined through the ultrasonic Doppler frequency shift.The efficacy of the proposed detection principle has been validated by mathematical models and finite element simulations.Various contaminants with diverse velocities were systematically tested within a 14mm diameter pipe.The experimental results demonstrate that the proposed sensor can effectively detect contaminants within the 0.5−3mm range,accurately distinguish contaminant types,and measure flow velocity.