BACKGROUND Sarcomatoid carcinoma is a rare subtype of non-small-cell lung cancer,commonly associated with locally advanced disease,early metastasis,and poor prognosis.Tongue metastasis from lung cancer is a rare condi...BACKGROUND Sarcomatoid carcinoma is a rare subtype of non-small-cell lung cancer,commonly associated with locally advanced disease,early metastasis,and poor prognosis.Tongue metastasis from lung cancer is a rare condition that may occur in advanced stage of the disease.CASE SUMMARY The patient was a 70-year-old female with a history of resected pulmonary sarcomatoid carcinoma(PSC)who presented with subacute tongue swelling,imparting the clinical impression of a lingual abscess.However,histologic examination of the partial glossectomy revealed a high-grade,poorly differentiated spindle and epithelioid carcinoma consistent with metastatic PSC.CONCLUSION Although uncommon,clinicians should be cognizant of the possibility of a metastatic process to the tongue mimicking a benign or inflammatory process.A high index of suspicion for metastatic disease should be maintained when tongue swelling is observed in patients with a known history of PSC.展开更多
We compile a blue AGN sample from SDSS and investigate how the ratio of hard X-ray to bolometric luminosity depends on the Eddington ratio and black hole mass. Our sample comprises 240 radio-quiet Seyfert 1 galaxies a...We compile a blue AGN sample from SDSS and investigate how the ratio of hard X-ray to bolometric luminosity depends on the Eddington ratio and black hole mass. Our sample comprises 240 radio-quiet Seyfert 1 galaxies and QSOs. We find that the fraction of hard X-ray luminosity （log（L2-10keV/L bol）） decreases with an increase of the Eddington ratio. We also find that the fraction of hard X-ray luminosity is independent of the black hole mass for radio-quiet AGNs. The relation of log（L2-10 keV/Lbol） decreasing with increasing Eddington ratio indicates that X-ray bolometric correction is not a constant, from a larger sample supporting the results of Vasudevan ＆ Fabian. We interpret our results by the disk corona evaporation/condensation model. In the frame work of this model, Compton cooling becomes efficient in cooling the corona at high accretion rates （in units of Eddington rate）, leading to condensation of coronal gas to the disk. Consequently, the relative strength of the corona to the disk becomes weaker at higher Eddington ratios. Therefore, the fraction of hard X-ray emission to disk emission and hence to the bolometric emission is smaller at higher Eddington ratios. The independence of the fraction of hard X-ray luminosity with respect to the mass of the black hole can also be explained by the disk corona model since the coronal structure and luminosity （in units of Eddington luminosity） are independent of the mass of black holes.展开更多
文摘BACKGROUND Sarcomatoid carcinoma is a rare subtype of non-small-cell lung cancer,commonly associated with locally advanced disease,early metastasis,and poor prognosis.Tongue metastasis from lung cancer is a rare condition that may occur in advanced stage of the disease.CASE SUMMARY The patient was a 70-year-old female with a history of resected pulmonary sarcomatoid carcinoma(PSC)who presented with subacute tongue swelling,imparting the clinical impression of a lingual abscess.However,histologic examination of the partial glossectomy revealed a high-grade,poorly differentiated spindle and epithelioid carcinoma consistent with metastatic PSC.CONCLUSION Although uncommon,clinicians should be cognizant of the possibility of a metastatic process to the tongue mimicking a benign or inflammatory process.A high index of suspicion for metastatic disease should be maintained when tongue swelling is observed in patients with a known history of PSC.
基金Supported by the National Natural Science Foundation of China (Grant Nos.10533050 and 10773028)the National Basic Research Program of China-973 Program 2009CB824800
文摘We compile a blue AGN sample from SDSS and investigate how the ratio of hard X-ray to bolometric luminosity depends on the Eddington ratio and black hole mass. Our sample comprises 240 radio-quiet Seyfert 1 galaxies and QSOs. We find that the fraction of hard X-ray luminosity （log（L2-10keV/L bol）） decreases with an increase of the Eddington ratio. We also find that the fraction of hard X-ray luminosity is independent of the black hole mass for radio-quiet AGNs. The relation of log（L2-10 keV/Lbol） decreasing with increasing Eddington ratio indicates that X-ray bolometric correction is not a constant, from a larger sample supporting the results of Vasudevan ＆ Fabian. We interpret our results by the disk corona evaporation/condensation model. In the frame work of this model, Compton cooling becomes efficient in cooling the corona at high accretion rates （in units of Eddington rate）, leading to condensation of coronal gas to the disk. Consequently, the relative strength of the corona to the disk becomes weaker at higher Eddington ratios. Therefore, the fraction of hard X-ray emission to disk emission and hence to the bolometric emission is smaller at higher Eddington ratios. The independence of the fraction of hard X-ray luminosity with respect to the mass of the black hole can also be explained by the disk corona model since the coronal structure and luminosity （in units of Eddington luminosity） are independent of the mass of black holes.
