This project implemented the Stroke1-2-0 stroke awareness programme across China and investigated its impact over a 2-year period.We initiated the Stroke1-2-0 educational campaign and Stroke1-2-0 special task forces(S...This project implemented the Stroke1-2-0 stroke awareness programme across China and investigated its impact over a 2-year period.We initiated the Stroke1-2-0 educational campaign and Stroke1-2-0 special task forces(STF)across the nation.Massive media coverage,community-based educational sessions with videos and other related materials and induction of Stroke1-2-0 STF were the major means of promotion.We delivered a survey at the end of 2016 and 2018 to evaluate the impact of our effort.A total of 3066 participants responded to the first survey in 2016,and 15207 participants responded in 2018 across China.The acceptance rate for Stroke1-2-0 versus FAST(an English-language stroke awareness tool)was 50.2%versus 19.1%in 2016,and changed significantly to 82.2%versus 8.0%in 2018(p<0.001).Stroke1-2-0 was well accepted by all ages and by people with different academic qualifications.Only 6.5%of survey respondents were aware that there was a therapeutic window for thrombolytic therapy in 2016,but this awareness increased significantly to 32.8%in 2018.Only 12.6%of people in 2016 indicated that they would send patients with stroke to the nearest hospital capable of performing thrombolytic therapy,but there was a nearly threefold increase(52.5%)in this number by 2018.More than 1000 major hospitals joined the Stroke1-2-0 STF,and more than 20000‘stroke warriors’have joined our stroke awareness improvement effort so far.Stroke1-2-0 stroke awareness programme is well-implemented and accepted,and is generating profound improvement in stroke awareness in China.展开更多
Exposure to greenness may lead to a wide range of beneficial health outcomes.However,the effects of greenness on preterm birth(PTB)are inconsistent,and limited studies have focused on the subcategories of PTB.A total ...Exposure to greenness may lead to a wide range of beneficial health outcomes.However,the effects of greenness on preterm birth(PTB)are inconsistent,and limited studies have focused on the subcategories of PTB.A total of 3,751,672 singleton births from a national birth cohort in China's Mainland were included in this study.Greenness was estimated using the satellitebased Normalized Difference Vegetation Index(NDVI)and Enhanced Vegetation Index with 500-m and 1,000-m buffers around participants’addresses.The subcategories of PTB(20-36 weeks)included extremely PTB(EPTB,20-27 weeks).展开更多
Preterm birth(PTB)is a leading cause of perinatal mortality and morbidity worldwide[1].Since maternal and fetal health protection has been included in the United Nations Sustainable Development Goals,identification of...Preterm birth(PTB)is a leading cause of perinatal mortality and morbidity worldwide[1].Since maternal and fetal health protection has been included in the United Nations Sustainable Development Goals,identification of modifiable risk factors for PTB is particularly crucial.The Global Burden of Disease(GBD)Study 2019 recognized fine particulate matter(PM2.5)pollution as a risk factor for decreased gestational age and low birth weight.展开更多
The nitrogen-doped carbon derived from graphitic carbon nitride(g-C_(3)N_(4))has been widely deployed in activating peroxymonosulfate(PMS)to remove organic pollutants.However,the instability of g-C_(3)N_(4)at high tem...The nitrogen-doped carbon derived from graphitic carbon nitride(g-C_(3)N_(4))has been widely deployed in activating peroxymonosulfate(PMS)to remove organic pollutants.However,the instability of g-C_(3)N_(4)at high temperature brings challenges to the preparation of materials.The nitrogen-doped graphitic carbon nanosheets(N-GC750)were synthesized by magnesium thermal denitrification.Magnesium undergoes the displacement reaction with small molecules produced by the pyrolysis of g-C_(3)N_(4),thereby effectively fixing carbon on the in-situ template of Mg_(3)N_(2)and avoiding direct product volatilization.N-GC750 exhibited excellent performance during the PMS activation process and bisphenol A(BPA,0.2 g/L)could be thoroughly removed in 30 min.A wide range of pH(3–11),temperature(10–40℃)and common anions were employed in studying the impact on system.Additionally,N-GC750 showed satisfactory reusability in cycle tests and promising applicability in real water samples.Quenching experiments and electron paramagnetic resonance(EPR)measurements indicated that singlet oxygen was the main active species coupled with partial electron transfer in N-GC750/PMS system.Furtherly,the oxidation products were identified,and their ecotoxicity was evaluated.This work is expected to provide a reference for the feasibility of preparing g-C_(3)N_(4)derived carbon materials and meaningful for PMS activation.展开更多
基金We appreciate the following funding support from the National Natural Science Foundation of China(81572232,PI:JZ)Shanghai Natural Science Foundation(17dz2308400,PI:JZ)China Research Engagement Funding of the University of Pennsylvania(CREF-030,PI:RL).
文摘This project implemented the Stroke1-2-0 stroke awareness programme across China and investigated its impact over a 2-year period.We initiated the Stroke1-2-0 educational campaign and Stroke1-2-0 special task forces(STF)across the nation.Massive media coverage,community-based educational sessions with videos and other related materials and induction of Stroke1-2-0 STF were the major means of promotion.We delivered a survey at the end of 2016 and 2018 to evaluate the impact of our effort.A total of 3066 participants responded to the first survey in 2016,and 15207 participants responded in 2018 across China.The acceptance rate for Stroke1-2-0 versus FAST(an English-language stroke awareness tool)was 50.2%versus 19.1%in 2016,and changed significantly to 82.2%versus 8.0%in 2018(p<0.001).Stroke1-2-0 was well accepted by all ages and by people with different academic qualifications.Only 6.5%of survey respondents were aware that there was a therapeutic window for thrombolytic therapy in 2016,but this awareness increased significantly to 32.8%in 2018.Only 12.6%of people in 2016 indicated that they would send patients with stroke to the nearest hospital capable of performing thrombolytic therapy,but there was a nearly threefold increase(52.5%)in this number by 2018.More than 1000 major hospitals joined the Stroke1-2-0 STF,and more than 20000‘stroke warriors’have joined our stroke awareness improvement effort so far.Stroke1-2-0 stroke awareness programme is well-implemented and accepted,and is generating profound improvement in stroke awareness in China.
基金This work was supported by the National Key Research and Development Program of China(2016YFC1000102 and 2016YFC1000307),and supported by a grant from the State Key Laboratory of Resources and the Environmental Information System.
文摘Exposure to greenness may lead to a wide range of beneficial health outcomes.However,the effects of greenness on preterm birth(PTB)are inconsistent,and limited studies have focused on the subcategories of PTB.A total of 3,751,672 singleton births from a national birth cohort in China's Mainland were included in this study.Greenness was estimated using the satellitebased Normalized Difference Vegetation Index(NDVI)and Enhanced Vegetation Index with 500-m and 1,000-m buffers around participants’addresses.The subcategories of PTB(20-36 weeks)included extremely PTB(EPTB,20-27 weeks).
基金supported by the National Key Research and Development Program of China(2016YFC1000102,2016YFC1000307,and 2016YFC0206202)National Natural Science Foundation of China(91543114)+1 种基金Natural Science Foundation of Shanghai(20ZR1402900)a grant from State Key Laboratory of Resources and Environmental Information System。
文摘Preterm birth(PTB)is a leading cause of perinatal mortality and morbidity worldwide[1].Since maternal and fetal health protection has been included in the United Nations Sustainable Development Goals,identification of modifiable risk factors for PTB is particularly crucial.The Global Burden of Disease(GBD)Study 2019 recognized fine particulate matter(PM2.5)pollution as a risk factor for decreased gestational age and low birth weight.
基金the Science and Technology Commission of Shanghai Municipality(Nos.21ZR1425200,18020500800,18JC1412900 and 19DZ2271100)。
文摘The nitrogen-doped carbon derived from graphitic carbon nitride(g-C_(3)N_(4))has been widely deployed in activating peroxymonosulfate(PMS)to remove organic pollutants.However,the instability of g-C_(3)N_(4)at high temperature brings challenges to the preparation of materials.The nitrogen-doped graphitic carbon nanosheets(N-GC750)were synthesized by magnesium thermal denitrification.Magnesium undergoes the displacement reaction with small molecules produced by the pyrolysis of g-C_(3)N_(4),thereby effectively fixing carbon on the in-situ template of Mg_(3)N_(2)and avoiding direct product volatilization.N-GC750 exhibited excellent performance during the PMS activation process and bisphenol A(BPA,0.2 g/L)could be thoroughly removed in 30 min.A wide range of pH(3–11),temperature(10–40℃)and common anions were employed in studying the impact on system.Additionally,N-GC750 showed satisfactory reusability in cycle tests and promising applicability in real water samples.Quenching experiments and electron paramagnetic resonance(EPR)measurements indicated that singlet oxygen was the main active species coupled with partial electron transfer in N-GC750/PMS system.Furtherly,the oxidation products were identified,and their ecotoxicity was evaluated.This work is expected to provide a reference for the feasibility of preparing g-C_(3)N_(4)derived carbon materials and meaningful for PMS activation.
