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Development and validation of a nomogram prediction model for the risk of parastomal hernia
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作者 huasheng Liu Weiqin Wang +5 位作者 Chen Qin Hongxia Wang Wei Qi Yanhua Wei Longbo Zheng jilin hu 《Intelligent Medicine》 EI CSCD 2024年第2期128-133,共6页
Background Parastomal hernia is one of the potential complications after enterostomy.There is currently no early risk assessment tool for parastomal hernia.Methods The current investigation was conducted using retrosp... Background Parastomal hernia is one of the potential complications after enterostomy.There is currently no early risk assessment tool for parastomal hernia.Methods The current investigation was conducted using retrospective studies.A total of 302 cases were used develop and internally to validate a nomogram prediction model,and 67 cases were used for external validation.Independent risk factors for parastomal hernia after permanent sigmoid colostomy were assessed via univariate analysis and binary logistic regression analysis.The nomogram prediction model was established based on independent risk factors.Results Body mass index,serum albumin,age,sex,and stoma diameter were independent risk factors for parastomal hernia.The areas under the receiver operating characteristic curves were 0.909 in the development group and 0.801 in the validation group.The Hosmer-Lemeshow test(P>0.05)and calibration curves indicated good consistency between actual observations and predicted probabilities.Conclusions A nomogram prediction model was constructed and validated based on risk factors for parastomal hernia.The nomogram could be generalized to patients undergoing surgery for stoma by specialized surgeons to provide relevant references for stoma patients. 展开更多
关键词 NOMOGRAM Parastomal hernia Risk factors
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新型Fe3O4@MoO3@GdF3:Eu3+磁-光双模态成像材料的合成及性能 被引量:1
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作者 龙爱春 彭红霞 +3 位作者 胡继林 贺爱兰 陈占军 彭秧锡 《科学通报》 EI CAS CSCD 北大核心 2019年第21期2245-2253,共9页
针对现有磁-光双模态成像材料灵敏度低与穿透深度不足的缺陷,通过引入局域表面等离子体共振(LSPR)效应的隔层的方法,成功制备了新型Fe3O4@MoO3@GdF3:Eu^3+磁-光双模态成像材料. XRD分析结果表明, Fe3O4表面逐层包覆上了结晶良好的单斜... 针对现有磁-光双模态成像材料灵敏度低与穿透深度不足的缺陷,通过引入局域表面等离子体共振(LSPR)效应的隔层的方法,成功制备了新型Fe3O4@MoO3@GdF3:Eu^3+磁-光双模态成像材料. XRD分析结果表明, Fe3O4表面逐层包覆上了结晶良好的单斜晶系的MoO3和正交晶系的GdF3:Eu^3+纳米晶.荧光光谱分析表明,该材料具有良好的发光性,以593nm附近的5D0→7F1磁偶极跃迁为最强发射峰.而该材料的磁饱和强度仍为25.9 emu/g. MTT和MRI分析结果表明, Fe3O4@MoO3@GdF3:Eu^3+磁-光双模态成像材料具有低毒性和较好的核磁共振成像效果.该方法将解决磁-光双模态成像材料性能方面的瓶颈问题,为推进该类材料在肿瘤精准诊疗和光学共聚焦显微技术中的应用提供理论依据和实验基础. 展开更多
关键词 LSPR效应 Fe3O4@MoO3@GdF3:Eu^3+ 磁性 发光 毒性
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