Background:To evaluate the association between corneal central endothelial cell count(CECC)with reactivity for hepatitis B virus(HBV),hepatitis C virus(HCV),human immunodeficiency virus(HIV),human T-lymphotropic virus...Background:To evaluate the association between corneal central endothelial cell count(CECC)with reactivity for hepatitis B virus(HBV),hepatitis C virus(HCV),human immunodeficiency virus(HIV),human T-lymphotropic virus-1(HTLV1),and syphilis from an eye bank database.Methods:Eye bank data included 19,159 donors and 38,318 corneas screened for HBV,HCV,HIV,HTLV1,and syphilis from July 2007-May 2015.Linear and binary mixed effects models were used to determine the adjusted marginal effect a positive viral screening test had on CECC and morphology,respectively.The models were adjusted for age,race,gender,lens status,and death to preservation.Eyes with missing data were excluded from the analysis.Statistical significance was defined as P values<0.05.Results:A total of 18,097 donors and 35,136 corneas were included in the final analysis.Average CECC for eyes with negative viral screening was 2,597±436 while the average CECC for eyes screening positive for syphilis,HBV,HCV,HIV,and HTLV1 were 2,638±392(P=0.073),2,569±419(P=0.815),2,603±363(P=0.207),2,615±360(P=0.733),and 2,625±436(P=0.362)respectively.Conclusions:The presence of HBV,HCV,HIV,HTLV1,and syphilis display no association with a statistically significant difference in CECC when compared to normal non-diseased donors.展开更多
Cataract surgery is one of the most commonly performed surgeries among the elderly today.The volume of cataract surgeries has dramatically increased in the past few decades due to technological advancements leading to...Cataract surgery is one of the most commonly performed surgeries among the elderly today.The volume of cataract surgeries has dramatically increased in the past few decades due to technological advancements leading to decreased morbidity,better overall outcomes,and increased expectation for correction of refractive error and spectacle independence after cataract surgery.The number of cataract surgeries is expected to continue to rise with the increase of the elderly population.Thus,accurate predictions of intraocular lens(IOL)power and the ability to correct for any postoperative refractive errors are critical.Despite the improved ability of cataract surgeons to accurately calculate IOL power,postoperative refractive errors still do occur due to various reasons such as imperfect preoperative measurements,toric-lens misalignment,and existing or surgically-induced astigmatism.The aim of this article is to review the various surgical options,including intraocular and corneal refractive surgical approaches,to correct post-operative refractive errors after cataract surgery.展开更多
基金Publication of this article was supported by a Research to Prevent Blindness unrestricted core grant(Albert Einstein College of Medicine-Grant number:340844).
文摘Background:To evaluate the association between corneal central endothelial cell count(CECC)with reactivity for hepatitis B virus(HBV),hepatitis C virus(HCV),human immunodeficiency virus(HIV),human T-lymphotropic virus-1(HTLV1),and syphilis from an eye bank database.Methods:Eye bank data included 19,159 donors and 38,318 corneas screened for HBV,HCV,HIV,HTLV1,and syphilis from July 2007-May 2015.Linear and binary mixed effects models were used to determine the adjusted marginal effect a positive viral screening test had on CECC and morphology,respectively.The models were adjusted for age,race,gender,lens status,and death to preservation.Eyes with missing data were excluded from the analysis.Statistical significance was defined as P values<0.05.Results:A total of 18,097 donors and 35,136 corneas were included in the final analysis.Average CECC for eyes with negative viral screening was 2,597±436 while the average CECC for eyes screening positive for syphilis,HBV,HCV,HIV,and HTLV1 were 2,638±392(P=0.073),2,569±419(P=0.815),2,603±363(P=0.207),2,615±360(P=0.733),and 2,625±436(P=0.362)respectively.Conclusions:The presence of HBV,HCV,HIV,HTLV1,and syphilis display no association with a statistically significant difference in CECC when compared to normal non-diseased donors.
文摘Cataract surgery is one of the most commonly performed surgeries among the elderly today.The volume of cataract surgeries has dramatically increased in the past few decades due to technological advancements leading to decreased morbidity,better overall outcomes,and increased expectation for correction of refractive error and spectacle independence after cataract surgery.The number of cataract surgeries is expected to continue to rise with the increase of the elderly population.Thus,accurate predictions of intraocular lens(IOL)power and the ability to correct for any postoperative refractive errors are critical.Despite the improved ability of cataract surgeons to accurately calculate IOL power,postoperative refractive errors still do occur due to various reasons such as imperfect preoperative measurements,toric-lens misalignment,and existing or surgically-induced astigmatism.The aim of this article is to review the various surgical options,including intraocular and corneal refractive surgical approaches,to correct post-operative refractive errors after cataract surgery.
