目的分析三维可变翻转角快速自旋回波序列(3D-sampling perfection with application-optimized contrasts by using different flip angle evolutions,3D-SPACE)联合三维时间飞跃法磁共振血管成像(3D-time of flight magnetic resonanc...目的分析三维可变翻转角快速自旋回波序列(3D-sampling perfection with application-optimized contrasts by using different flip angle evolutions,3D-SPACE)联合三维时间飞跃法磁共振血管成像(3D-time of flight magnetic resonance angiography,3D-TOF-MRA)融合技术在行伽马刀治疗前对三叉神经显示、定位的精准性。方法选取西安大兴医院临床诊断为三叉神经痛拟行伽马刀治疗的患者28例,均行3D-SPACE及3D-TOF-MRA成像,观察三叉神经颅内段与邻近神经血管的关系,评估术前两种序列融合技术对三叉神经血管压迫的检出率及精准性。结果28例患者中,3D-SPACE联合3D-TOF-MRA序列融合技术检出有症状侧三叉神经血管压迫28例,其中右侧17例(2级2例,3级8例,4级7例),左侧11例(3级3例,4级8例),检出率为100%。结论3D-SPACE联合3D-TOF-MRA序列融合技术可以清晰显示三叉神经颅内段与周围神经血管的位置关系,为伽马刀治疗靶区勾画可提供精准的定位信息。展开更多
With the increasing plant area of welsh onion, onion and Chinese onion, the damage of Thrips tabaci in Yanji City is aggravating day by day. Through preliminary investigation and literature reading, we summarized occu...With the increasing plant area of welsh onion, onion and Chinese onion, the damage of Thrips tabaci in Yanji City is aggravating day by day. Through preliminary investigation and literature reading, we summarized occurrence status, morphological characteristics, damage characteristics, occurrence regularity, living habit, outbreak cause and integrated control technology of T. tabaci in Yanji City, in order to control the hazard of T. tabaci effectively.展开更多
To compare efficacy and safety of nab-paclitaxel plus gemcitabine(AG)with nab-paclitaxel plus S-1(AS)as first-line treatment for metastatic pancreatic cancer,we conducted a retrospective analysis by reviewing medical ...To compare efficacy and safety of nab-paclitaxel plus gemcitabine(AG)with nab-paclitaxel plus S-1(AS)as first-line treatment for metastatic pancreatic cancer,we conducted a retrospective analysis by reviewing medical records of 53 metastatic pancreatic cancer patients in our institution.They received either AG(nab-paclitaxel 125 mg/m 2 on days 1,8 and gemcitabine 1000 mg/m 2 on days 1,8)or AS(nab-paclitaxel 125 mg/m 2 on days 1,8 and S-180-120 mg on days 1-14)chemotherapy.We found that AS had higher objective response rate(36%vs 21.4%),better disease control rate(84%vs 75%),prolonged time to progression(TTP,7.1 vs 5 months),and improved overall survival(OS,15.3 vs 12 months)when compared with AG.In Cox proportional hazards model,sex was significantly associated with TTP(P value=.031)and metastatic sites plus treatment after progression were significantly associated with OS(P value=.028 and.01,respectively).The incidence rate of chemotherapy-related adverse events was similar in both groups.Neutropenia(50%and 60%,all grade;21.4%and 36%,grade 3 or 4,in AG and AS group)and sensory neuropathy(21.4%and 24%,all grade;3.6%and 4%,grade 3 or 4,in AG and AS group)were the most common hematologic and non-hematologic toxicity.Thus,we believed that AS is a reasonable and convenient alternative for patients treated with AG as first-line chemotherapy for metastatic pancreatic cancer.展开更多
文摘目的分析三维可变翻转角快速自旋回波序列(3D-sampling perfection with application-optimized contrasts by using different flip angle evolutions,3D-SPACE)联合三维时间飞跃法磁共振血管成像(3D-time of flight magnetic resonance angiography,3D-TOF-MRA)融合技术在行伽马刀治疗前对三叉神经显示、定位的精准性。方法选取西安大兴医院临床诊断为三叉神经痛拟行伽马刀治疗的患者28例,均行3D-SPACE及3D-TOF-MRA成像,观察三叉神经颅内段与邻近神经血管的关系,评估术前两种序列融合技术对三叉神经血管压迫的检出率及精准性。结果28例患者中,3D-SPACE联合3D-TOF-MRA序列融合技术检出有症状侧三叉神经血管压迫28例,其中右侧17例(2级2例,3级8例,4级7例),左侧11例(3级3例,4级8例),检出率为100%。结论3D-SPACE联合3D-TOF-MRA序列融合技术可以清晰显示三叉神经颅内段与周围神经血管的位置关系,为伽马刀治疗靶区勾画可提供精准的定位信息。
基金Supported by Science and Technology Development Project of Yanbian University(2013-34)
文摘With the increasing plant area of welsh onion, onion and Chinese onion, the damage of Thrips tabaci in Yanji City is aggravating day by day. Through preliminary investigation and literature reading, we summarized occurrence status, morphological characteristics, damage characteristics, occurrence regularity, living habit, outbreak cause and integrated control technology of T. tabaci in Yanji City, in order to control the hazard of T. tabaci effectively.
基金This study was supported by Shanghai Hospital Development Center(SHDC12017X04).
文摘To compare efficacy and safety of nab-paclitaxel plus gemcitabine(AG)with nab-paclitaxel plus S-1(AS)as first-line treatment for metastatic pancreatic cancer,we conducted a retrospective analysis by reviewing medical records of 53 metastatic pancreatic cancer patients in our institution.They received either AG(nab-paclitaxel 125 mg/m 2 on days 1,8 and gemcitabine 1000 mg/m 2 on days 1,8)or AS(nab-paclitaxel 125 mg/m 2 on days 1,8 and S-180-120 mg on days 1-14)chemotherapy.We found that AS had higher objective response rate(36%vs 21.4%),better disease control rate(84%vs 75%),prolonged time to progression(TTP,7.1 vs 5 months),and improved overall survival(OS,15.3 vs 12 months)when compared with AG.In Cox proportional hazards model,sex was significantly associated with TTP(P value=.031)and metastatic sites plus treatment after progression were significantly associated with OS(P value=.028 and.01,respectively).The incidence rate of chemotherapy-related adverse events was similar in both groups.Neutropenia(50%and 60%,all grade;21.4%and 36%,grade 3 or 4,in AG and AS group)and sensory neuropathy(21.4%and 24%,all grade;3.6%and 4%,grade 3 or 4,in AG and AS group)were the most common hematologic and non-hematologic toxicity.Thus,we believed that AS is a reasonable and convenient alternative for patients treated with AG as first-line chemotherapy for metastatic pancreatic cancer.
