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养心安眠胶囊治疗心气虚的量效关系研究
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作者 付立娟 金德祥 +5 位作者 边雨 曲佳乐 张秋娟 郭敏 高陆 崔宪利 《特产研究》 2024年第1期9-12,共4页
为研究养心安眠胶囊治疗心气虚的药理作用和量效关系。本研究采用“惊劳、饥饿结合损耗心气”方法,建立小鼠心气虚模型,设计空白组、模型组、阳性药组、养心安眠胶囊0.273 g/kg组、0.546 g/kg组、0.819 g/kg 3个给药组,通过检测小鼠游... 为研究养心安眠胶囊治疗心气虚的药理作用和量效关系。本研究采用“惊劳、饥饿结合损耗心气”方法,建立小鼠心气虚模型,设计空白组、模型组、阳性药组、养心安眠胶囊0.273 g/kg组、0.546 g/kg组、0.819 g/kg 3个给药组,通过检测小鼠游泳力竭时间、肿瘤坏死因子-α(TNF-α),心肌组织匀浆中超氧化物歧化酶(SOD)、丙二醛(MDA)、肌酸激酶(CK)、乳酸脱氢酶(LDH)等指标,研究养心安眠胶囊治疗心气虚的药理作用和量效关系。结果表明,与模型组相比,养心安眠胶囊0.273 g/kg组对小鼠游泳力竭时间、TNF-α、SOD、MDA无显著性影响(P> 0.05),但可显著降低CK、LDH水平(P<0.05);养心安眠胶囊0.546 g/kg组和0.819 g/kg组对各指标均有显著性影响(P<0.01),表现为明显延长小鼠游泳力竭时间、明显降低TNF-α、MDA、CK、LDH水平,显著提高SOD水平。表明养心安眠胶囊具有显著的治疗心气虚的药理作用,养心安眠胶囊给药剂量在0.273 g/kg~0.546g/kg范围内,有良好的量效相关性,在0.546 g/kg和0.819 g/kg给药剂量下药效作用明显。本研究为后期养心安眠胶囊临床用药提供理论参考。 展开更多
关键词 养心安眠胶囊 心气虚 量效关系
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THE CHANGING WORLD ECONOMY AND ASIA-PACIFIC COOPERATION
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作者 jin dexiang 《Contemporary International Relations》 1996年第10期1-12,共12页
Just at the turn of the century,mankind is experiencing a historical changein world economy,of which the following points are worthy of our close at-tention: 1.The momentum of the present vigorous economic growth in d... Just at the turn of the century,mankind is experiencing a historical changein world economy,of which the following points are worthy of our close at-tention: 1.The momentum of the present vigorous economic growth in developingcountries will continue to persist and make its impact upon the whole world,which will fundamentally transform the existing world economic pattern. 展开更多
关键词 ASIA In ASIA THE CHANGING WORLD ECONOMY AND ASIA-PACIFIC COOPERATION World US
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“YELLOW PERIL”—A HOAX THEN AND NOW
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作者 jin dexiang 《Contemporary International Relations》 1997年第7期1-1,共1页
Frenzied cries of“China threat”have once again cropped up in the West,withsome people in the US media shouting the loudest at a time when we are on thedawn of a new century.These gentlemen fly in the face of histori... Frenzied cries of“China threat”have once again cropped up in the West,withsome people in the US media shouting the loudest at a time when we are on thedawn of a new century.These gentlemen fly in the face of historical truth and al-lege that a resurgent China is posing a threat to its Asian neighbors and US. 展开更多
关键词 US A HOAX THEN AND NOW YELLOW PERIL
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