Objective: To investigate the distribution of Chinese medicine (CM) syndrome in patients with acute myocardial infarction (AMI) on admission and its impact on prognosis. Methods: A total of 525 AMI patients were prosp...Objective: To investigate the distribution of Chinese medicine (CM) syndrome in patients with acute myocardial infarction (AMI) on admission and its impact on prognosis. Methods: A total of 525 AMI patients were prospectively recruited and classified into 4 groups based on their clinical characteristics: excess-heat, excess-cold, deficiency-heat and deficiency-cold syndromes. Major adverse cardiovascular events (MACEs) were followed up. Results: The excess syndrome was more common than deficiency syndrome (72.95% vs. 27.05%;P<0.05). Totally 495 (94.29%) of 525 AMI patients were followed up (median 277 days). There were 59 (11.92%) MACEs. After adjusted with confounding factors in Cox regression models, the hazard ratio (95% confidence interval) of excess-heat, excess-cold, deficiency-heat and deficiency-cold syndrome groups were 1, 1.25 (0.63, 2.49;P<0.05), 2.37 (1.14, 4.94;P<0.05), 3.76 (1.71, 8.28;P<0.05), respectively. Conclusions: Excess syndrome was more common in AMI patients and had better prognosis, while deficiency-cold syndrome had the poorest prognosis. CM syndrome was of value in predicting long-term outcomes in AMI patients.展开更多
Evidence-based medicine (EBM) has been promoted in China for the past 2 decades and has had a great in-fluence on the field of medicine. Medical students, practitioners, and policy makers have employed evidence from w...Evidence-based medicine (EBM) has been promoted in China for the past 2 decades and has had a great in-fluence on the field of medicine. Medical students, practitioners, and policy makers have employed evidence from well-designed and well-conducted studies to optimize decision-making. This article summarizes the recent progress in EBM in China. Development of EBM in remote areas of China Ten years ago, many remote areas, such as Tibet, Xinjiang, the western edge of Yunnan Province, the northeast edge of Guizhou Province, and Western Sichuan Plateau, suffered from deep medical and social problems. There was a wide disparity in access to physicians practicing EBM between rural areas and big cities at that time.展开更多
基金Supported by the National Basic Research Program of China(No.2012CB518605)Science and Technology Innovative Program of Shanghai,China(No.10DZ1975400)
文摘Objective: To investigate the distribution of Chinese medicine (CM) syndrome in patients with acute myocardial infarction (AMI) on admission and its impact on prognosis. Methods: A total of 525 AMI patients were prospectively recruited and classified into 4 groups based on their clinical characteristics: excess-heat, excess-cold, deficiency-heat and deficiency-cold syndromes. Major adverse cardiovascular events (MACEs) were followed up. Results: The excess syndrome was more common than deficiency syndrome (72.95% vs. 27.05%;P<0.05). Totally 495 (94.29%) of 525 AMI patients were followed up (median 277 days). There were 59 (11.92%) MACEs. After adjusted with confounding factors in Cox regression models, the hazard ratio (95% confidence interval) of excess-heat, excess-cold, deficiency-heat and deficiency-cold syndrome groups were 1, 1.25 (0.63, 2.49;P<0.05), 2.37 (1.14, 4.94;P<0.05), 3.76 (1.71, 8.28;P<0.05), respectively. Conclusions: Excess syndrome was more common in AMI patients and had better prognosis, while deficiency-cold syndrome had the poorest prognosis. CM syndrome was of value in predicting long-term outcomes in AMI patients.
文摘Evidence-based medicine (EBM) has been promoted in China for the past 2 decades and has had a great in-fluence on the field of medicine. Medical students, practitioners, and policy makers have employed evidence from well-designed and well-conducted studies to optimize decision-making. This article summarizes the recent progress in EBM in China. Development of EBM in remote areas of China Ten years ago, many remote areas, such as Tibet, Xinjiang, the western edge of Yunnan Province, the northeast edge of Guizhou Province, and Western Sichuan Plateau, suffered from deep medical and social problems. There was a wide disparity in access to physicians practicing EBM between rural areas and big cities at that time.
