The development of nano-medicine has played a crucial role in the diagnosis and treatment of diseases[1–3].Its main research area is the targeted delivery of therapeutic drugs or diagnostic reagents using nanotechnol...The development of nano-medicine has played a crucial role in the diagnosis and treatment of diseases[1–3].Its main research area is the targeted delivery of therapeutic drugs or diagnostic reagents using nanotechnology[4,5].However,the current drug delivery nano-carriers lack the driving force and navigation function required for targeted delivery and tissue penetration,and mainly rely on systemic circulation to deliver drugs[6,7].Therefore,it is necessary to increase the drug dosage to achieve sufficient enrichment of the focus tissue,which will undoubtedly increase the toxicity and side effects[8,9].In order to deliver drugs more accurately.展开更多
基金supported by the National Natural Science Foundation of China(32201145)Xiamen medical and health guidance project for funding(3502Z20209144).
文摘The development of nano-medicine has played a crucial role in the diagnosis and treatment of diseases[1–3].Its main research area is the targeted delivery of therapeutic drugs or diagnostic reagents using nanotechnology[4,5].However,the current drug delivery nano-carriers lack the driving force and navigation function required for targeted delivery and tissue penetration,and mainly rely on systemic circulation to deliver drugs[6,7].Therefore,it is necessary to increase the drug dosage to achieve sufficient enrichment of the focus tissue,which will undoubtedly increase the toxicity and side effects[8,9].In order to deliver drugs more accurately.
