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Itinerant ferromagnetism entrenched by the anisotropy of spin-orbit coupling in a dipolar Fermi gas
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作者 Xue-Jing Feng jin-xin li +7 位作者 Lu Qin Ying-Ying Zhang ShiQiang Xia Lu Zhou ChunJie Yang ZunLue Zhu Wu-Ming liu Xing-Dong Zhao 《Frontiers of physics》 SCIE CSCD 2023年第5期227-235,共9页
We investigate the itinerant ferromagnetism in a dipolar Fermi atomic system with the anisotropic spin–orbit coupling(SOC),which is traditionally explored with isotropic contact interaction.We first study the ferroma... We investigate the itinerant ferromagnetism in a dipolar Fermi atomic system with the anisotropic spin–orbit coupling(SOC),which is traditionally explored with isotropic contact interaction.We first study the ferromagnetism transition boundaries and the properties of the ground states through the density and spin-flip distribution in momentum space,and we find that both the anisotropy and the magnitude of the SOC play an important role in this process.We propose a helpful scheme and a quantum control method which can be applied to conquering the difficulties of previous experimental observation of itinerant ferromagnetism.Our further study reveals that exotic Fermi surfaces and an abnormal phase region can exist in this system by controlling the anisotropy of SOC,which can provide constructive suggestions for the research and the application of a dipolar Fermi gas.Furthermore,we also calculate the ferromagnetism transition temperature and novel distributions in momentum space at finite temperature beyond the ground states from the perspective of experiment. 展开更多
关键词 itinerant ferromagnetism spin-orbit coupling cold atom quantum simulation dipolar Fermi gas dipole-dipole interaction
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蛋白酪氨酸磷酸酶1B在乳腺癌进展中的作用(英文) 被引量:2
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作者 Shi-chong liAO jin-xin li +1 位作者 li YU Sheng-rong SUN 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2017年第4期334-342,共9页
目的:讨论蛋白酪氨酸磷酸酶1B(PTP1B)在乳腺癌中的表达模式,及其在肿瘤进展中所起的作用。创新点:首次证明了PTP1B能够增加非磷酸化信号转导与转录激活因子3(STAT3)的水平,而非磷酸化STAT3与核转录因子(NF-κB)形成新的转录因子介导C-C... 目的:讨论蛋白酪氨酸磷酸酶1B(PTP1B)在乳腺癌中的表达模式,及其在肿瘤进展中所起的作用。创新点:首次证明了PTP1B能够增加非磷酸化信号转导与转录激活因子3(STAT3)的水平,而非磷酸化STAT3与核转录因子(NF-κB)形成新的转录因子介导C-C型趋化因子配体5(CCL5)的表达,从而促进肿瘤细胞增殖和迁移,导致肿瘤恶性程度增加。方法:收集67名乳腺癌患者的癌组织和癌旁组织标本,并记录患者临床病理学特征,使用蛋白质免疫印迹法(Western blot)检测乳腺癌组织及癌旁组织PTP1B含量;研究PTP1B水平与患者临床病理特征关系;制作PTP1B基因敲除MCF-7细胞系,分别使用细胞生长实验、Transwell细胞迁移实验和划痕活力实验检测基因敲出组与对照组细胞增殖及迁移能力,使用Western blot检测两组细胞中磷酸化与非磷酸化STAT3表达水平和CCL5表达水平。结论:大约70%乳腺癌患者高表达PTP1B,并且随着患者TNM分期增加,患者PTP1B表达水平不断增加,同时PTP1B高表达与ER-、PR-和HER2+相关(表1和2);与对照组相比,PTP1B基因敲除组中肿瘤细胞增殖及迁移能力明显下降(图2和3),同时PTP1B可以通过上调STAT3非磷酸化水平来提高CCL5的表达,从而加快乳腺癌发生及发展(图4)。总之,PTP1B对乳腺癌的发生起到至关重要的作用。 展开更多
关键词 蛋白酪氨酸磷酸酶1B (PTP1B) 信号转导与转录激活因子3 (STAT3) 乳腺癌 肿瘤发生
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Production of Active Compounds in Medicinal Plants:From Plant Tissue Culture to Biosynthesis 被引量:7
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作者 Juan Wang Jian-li li +4 位作者 Jing li jin-xin li Shu-jie liu Lu-qi Huang Wen-yuan Gao 《Chinese Herbal Medicines》 CAS 2017年第2期115-125,共11页
Over past decades plant tissue culture has emerged as an alternative of whole plant cultivation in the production of valuable secondary metabolites.Adventitious roots culture of Panax ginseng and Echinacea purpure has... Over past decades plant tissue culture has emerged as an alternative of whole plant cultivation in the production of valuable secondary metabolites.Adventitious roots culture of Panax ginseng and Echinacea purpure has reached the scale of 1-10 kL.Some molecular biological techniques,such as transgenic technology and genetic stability are increasingly used in the studies on plant tissue cultures.The studies on elicitors have deepened into the induction mechanism,including signal molecules,functional genes,and so on.More and more biological elicitors,such as A.niger and yeast are used to increase the active compounds in plant tissue cultures.We also discussed the application of synthetic biology in the studies on biosynthesis of artemisinin,paclitaxel,and tanshinon.The studies on active ingredients biosynthesis of medicinal plants provide unprecedented possibilities to achieve mass production of active ingredients.Plant tissue cultures can not only produce active ingredients but also as experimental materials for biosynthesis.In order to improve the contents of active compounds in medicinal plants,following aspects could be carried out gene interference or gene silencing,gene overexpression,combination with chemical synthesis,application of elicitors,and site-directed mutagenesis of the key enzymes. 展开更多
关键词 biosynthesis functional gene medicinal plant tissue culture secondary metabolites
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